SG11202001387WA - Combination therapy of lasmiditan and a cgrp antagonist for use in the treatment of migraine - Google Patents
Combination therapy of lasmiditan and a cgrp antagonist for use in the treatment of migraineInfo
- Publication number
- SG11202001387WA SG11202001387WA SG11202001387WA SG11202001387WA SG11202001387WA SG 11202001387W A SG11202001387W A SG 11202001387WA SG 11202001387W A SG11202001387W A SG 11202001387WA SG 11202001387W A SG11202001387W A SG 11202001387WA SG 11202001387W A SG11202001387W A SG 11202001387WA
- Authority
- SG
- Singapore
- Prior art keywords
- lasmiditan
- migraine
- treatment
- combination therapy
- cgrp antagonist
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762554726P | 2017-09-06 | 2017-09-06 | |
| PCT/US2018/048730 WO2019050759A1 (en) | 2017-09-06 | 2018-08-30 | Combination therapy of lasmiditan and a cgrp antagonist for use in the treatment of migraine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202001387WA true SG11202001387WA (en) | 2020-03-30 |
Family
ID=63529021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202001387WA SG11202001387WA (en) | 2017-09-06 | 2018-08-30 | Combination therapy of lasmiditan and a cgrp antagonist for use in the treatment of migraine |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20200268735A1 (en) |
| EP (1) | EP3678665A1 (en) |
| JP (3) | JP6922092B2 (en) |
| KR (2) | KR20230025945A (en) |
| CN (3) | CN116059204A (en) |
| AU (1) | AU2018329568B2 (en) |
| BR (1) | BR112020002077A2 (en) |
| CA (1) | CA3073996C (en) |
| EA (1) | EA202090457A1 (en) |
| IL (1) | IL273031A (en) |
| MA (1) | MA50073A (en) |
| MX (2) | MX2020002554A (en) |
| SG (1) | SG11202001387WA (en) |
| TW (1) | TWI754772B (en) |
| WO (1) | WO2019050759A1 (en) |
| ZA (1) | ZA202000443B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2836649C (en) * | 2011-05-20 | 2020-06-23 | Alderbio Holdings Llc | Anti-cgrp compositions and use thereof |
| CN105960397B (en) | 2014-02-05 | 2020-09-04 | 默沙东公司 | Tablet formulations of CGRP-active compounds |
| TN2019000174A1 (en) | 2016-12-06 | 2020-10-05 | Colucid Pharmaceuticals Inc | Compositions and methods related to pyridinoylpiperidine 5-ht1f agonists |
| US20190374518A1 (en) * | 2018-06-08 | 2019-12-12 | Allergan Pharmaceuticals International Limited | Treatment of migraine |
| BR112021011546A2 (en) * | 2019-01-20 | 2021-08-31 | Biohaven Pharmaceutical Holding Company Ltd. | CGRP ANTAGONISTS FOR TREATMENT OF MIGRAINE CRISES |
| TWI776175B (en) | 2019-07-09 | 2022-09-01 | 美商美國禮來大藥廠 | Processes and intermediate for the large-scale preparation of 2,4,6-trifluoro-n-[6-(1-methyl-piperidine-4-carbonyl)-pyridin-2-yl]-benzamide hemisuccinate, and preparation of 2,4,6-trifluoro-n-[6-(1-methyl-piperidine-4-carbonyl)-pyridin-2-yl]-benzamide acetate |
| MX2023007575A (en) | 2020-12-22 | 2023-09-21 | Allergan Pharmaceuticals Int Ltd | Treatment of migraine. |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0002353D0 (en) * | 2000-06-22 | 2000-06-22 | Astrazeneca Ab | New use |
| TWI263497B (en) | 2002-03-29 | 2006-10-11 | Lilly Co Eli | Pyridinoylpiperidines as 5-HT1F agonists |
| CA2545771A1 (en) * | 2003-11-12 | 2005-05-26 | Nps Pharmaceuticals, Inc. | Migraine treatments including isovaleramide compounds and serotonin agonists |
| WO2011123654A1 (en) | 2010-04-02 | 2011-10-06 | Colucid Pharmaceuticals, Inc. | Compositions and methods of synthesis of pyridinoylpiperidine 5-ht1f agonists |
| AR081434A1 (en) * | 2010-06-10 | 2012-08-29 | Lilly Co Eli | ANTIBODY OF THE PEPTIDE RELATED TO THE CALCITONINE GENE (CGRP), PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, USE OF THE ANTIBODY TO PREPARE A USEFUL MEDICINAL PRODUCT TO TREAT PAIN OR MIGRANE PAIN AND ANOGEN ANOGEN FRAGMENT |
| AR104847A1 (en) * | 2015-06-17 | 2017-08-16 | Lilly Co Eli | FORMULATION OF ANTI-CGRP ANTIBODY |
| JP6937368B2 (en) * | 2016-09-23 | 2021-09-22 | テバ・ファーマシューティカルズ・インターナショナル・ゲー・エム・ベー・ハー | How to treat intractable migraine |
| US10766952B2 (en) * | 2017-03-02 | 2020-09-08 | Beth Israel Deaconess Medical Center, Inc. | Methods for reducing migraine frequency in a subject in need thereof |
-
2018
- 2018-08-29 TW TW107130051A patent/TWI754772B/en active
- 2018-08-30 EA EA202090457A patent/EA202090457A1/en unknown
- 2018-08-30 AU AU2018329568A patent/AU2018329568B2/en active Active
- 2018-08-30 KR KR1020237004878A patent/KR20230025945A/en not_active Application Discontinuation
- 2018-08-30 US US16/643,668 patent/US20200268735A1/en active Pending
- 2018-08-30 SG SG11202001387WA patent/SG11202001387WA/en unknown
- 2018-08-30 JP JP2020530455A patent/JP6922092B2/en active Active
- 2018-08-30 EP EP18766557.5A patent/EP3678665A1/en active Pending
- 2018-08-30 CN CN202310081233.8A patent/CN116059204A/en active Pending
- 2018-08-30 CN CN201880058157.6A patent/CN111032044A/en active Pending
- 2018-08-30 WO PCT/US2018/048730 patent/WO2019050759A1/en unknown
- 2018-08-30 CA CA3073996A patent/CA3073996C/en active Active
- 2018-08-30 KR KR1020207006231A patent/KR20200036919A/en not_active Application Discontinuation
- 2018-08-30 MX MX2020002554A patent/MX2020002554A/en unknown
- 2018-08-30 MA MA050073A patent/MA50073A/en unknown
- 2018-08-30 BR BR112020002077-0A patent/BR112020002077A2/en unknown
- 2018-08-30 CN CN202310675929.3A patent/CN116509861A/en active Pending
-
2020
- 2020-01-22 ZA ZA2020/00443A patent/ZA202000443B/en unknown
- 2020-03-03 IL IL273031A patent/IL273031A/en unknown
- 2020-03-05 MX MX2023008760A patent/MX2023008760A/en unknown
-
2021
- 2021-07-28 JP JP2021122905A patent/JP7183355B2/en active Active
-
2022
- 2022-11-22 JP JP2022186221A patent/JP7480261B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018329568A1 (en) | 2020-02-06 |
| JP2020530861A (en) | 2020-10-29 |
| CA3073996C (en) | 2022-05-31 |
| JP7183355B2 (en) | 2022-12-05 |
| EP3678665A1 (en) | 2020-07-15 |
| CN116059204A (en) | 2023-05-05 |
| CN111032044A (en) | 2020-04-17 |
| TWI754772B (en) | 2022-02-11 |
| MX2020002554A (en) | 2020-07-13 |
| JP2021176884A (en) | 2021-11-11 |
| JP7480261B2 (en) | 2024-05-09 |
| KR20200036919A (en) | 2020-04-07 |
| JP2023029872A (en) | 2023-03-07 |
| WO2019050759A1 (en) | 2019-03-14 |
| CA3073996A1 (en) | 2019-03-14 |
| IL273031A (en) | 2020-04-30 |
| EA202090457A1 (en) | 2020-06-10 |
| BR112020002077A2 (en) | 2020-07-28 |
| TW201919624A (en) | 2019-06-01 |
| AU2018329568B2 (en) | 2021-09-23 |
| US20200268735A1 (en) | 2020-08-27 |
| ZA202000443B (en) | 2022-07-27 |
| CN116509861A (en) | 2023-08-01 |
| KR20230025945A (en) | 2023-02-23 |
| JP6922092B2 (en) | 2021-08-18 |
| MA50073A (en) | 2020-07-15 |
| MX2023008760A (en) | 2023-08-02 |
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