SG11202000851YA - Method for producing therapeutic exosomes from nanoelectroporation and other non-endocytic cell transfection - Google Patents
Method for producing therapeutic exosomes from nanoelectroporation and other non-endocytic cell transfectionInfo
- Publication number
- SG11202000851YA SG11202000851YA SG11202000851YA SG11202000851YA SG11202000851YA SG 11202000851Y A SG11202000851Y A SG 11202000851YA SG 11202000851Y A SG11202000851Y A SG 11202000851YA SG 11202000851Y A SG11202000851Y A SG 11202000851YA SG 11202000851Y A SG11202000851Y A SG 11202000851YA
- Authority
- SG
- Singapore
- Prior art keywords
- nanoelectroporation
- cell transfection
- producing therapeutic
- therapeutic exosomes
- endocytic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/16—Microfluidic devices; Capillary tubes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Sustainable Development (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Electromagnetism (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Medical Informatics (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762541157P | 2017-08-04 | 2017-08-04 | |
| PCT/US2018/045333 WO2019028450A1 (en) | 2017-08-04 | 2018-08-06 | Method for producing therapeutic exosomes from nanoelectroporation and other non-endocytic cell transfection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202000851YA true SG11202000851YA (en) | 2020-02-27 |
Family
ID=65233122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202000851YA SG11202000851YA (en) | 2017-08-04 | 2018-08-06 | Method for producing therapeutic exosomes from nanoelectroporation and other non-endocytic cell transfection |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11674130B2 (en) |
| EP (1) | EP3661485A4 (en) |
| JP (2) | JP7420708B2 (en) |
| CN (2) | CN117987467A (en) |
| AU (1) | AU2018312099A1 (en) |
| CA (1) | CA3071553A1 (en) |
| IL (1) | IL272401A (en) |
| SG (1) | SG11202000851YA (en) |
| WO (1) | WO2019028450A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3752595A4 (en) | 2018-02-15 | 2021-12-08 | Ohio State Innovation Foundation | Microfluidic devices and methods for high throughput electroporation |
| JP2022543851A (en) * | 2019-08-06 | 2022-10-14 | オハイオ・ステイト・イノベーション・ファウンデーション | Therapeutic extracellular vesicles |
| CN111378685B (en) * | 2020-02-15 | 2023-10-31 | 深圳承启生物科技有限公司 | Method for preparing medicine-carrying exosome and medicine-carrying exosome |
| CN112226365A (en) * | 2020-10-13 | 2021-01-15 | 北京航空航天大学 | Nano-electroporation device based on single cell array and application thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7338796B1 (en) * | 2003-08-13 | 2008-03-04 | Sandia Corporation | Vesicle-based method and apparatus for collecting, manipulating, and chemically processing trace macromolecular species |
| US8524679B2 (en) * | 2006-11-08 | 2013-09-03 | Veritas Bio, Llc | In vivo delivery of double stranded RNA to a target cell |
| EP3569254B1 (en) * | 2009-04-17 | 2022-07-20 | Oxford University Innovation Limited | Composition for delivery of genetic material |
| CN102596177B (en) * | 2009-07-01 | 2014-05-28 | 阿昂梅迪克斯公司 | Microvesicles derived from nucleated, mammalian cells and use thereof |
| US9816086B2 (en) * | 2010-07-06 | 2017-11-14 | The Ohio State University | Dose and location controlled drug/gene/particle delivery to individual cells by nanoelectroporation |
| EP3037515A1 (en) * | 2014-12-28 | 2016-06-29 | Femtofab Co., Ltd. | Modified cell prepared by putting material into the cell without using delivery vehicle |
| WO2017054086A1 (en) * | 2015-10-01 | 2017-04-06 | Exerkine Corporation | Treatment of genetic myopathies using bioengineered exosomes |
-
2018
- 2018-08-06 CN CN202410102849.3A patent/CN117987467A/en active Pending
- 2018-08-06 JP JP2020505790A patent/JP7420708B2/en active Active
- 2018-08-06 CA CA3071553A patent/CA3071553A1/en active Pending
- 2018-08-06 US US16/635,471 patent/US11674130B2/en active Active
- 2018-08-06 WO PCT/US2018/045333 patent/WO2019028450A1/en unknown
- 2018-08-06 CN CN201880065004.4A patent/CN111194210B/en active Active
- 2018-08-06 AU AU2018312099A patent/AU2018312099A1/en active Pending
- 2018-08-06 SG SG11202000851YA patent/SG11202000851YA/en unknown
- 2018-08-06 EP EP18841065.8A patent/EP3661485A4/en active Pending
-
2020
- 2020-02-02 IL IL272401A patent/IL272401A/en unknown
-
2023
- 2023-09-20 JP JP2023152497A patent/JP2023164661A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP7420708B2 (en) | 2024-01-23 |
| JP2023164661A (en) | 2023-11-10 |
| US20210054359A1 (en) | 2021-02-25 |
| CA3071553A1 (en) | 2019-02-07 |
| EP3661485A1 (en) | 2020-06-10 |
| EP3661485A4 (en) | 2021-05-12 |
| JP2020529210A (en) | 2020-10-08 |
| IL272401A (en) | 2020-03-31 |
| AU2018312099A1 (en) | 2020-02-27 |
| US11674130B2 (en) | 2023-06-13 |
| CN111194210B (en) | 2024-02-20 |
| CN111194210A (en) | 2020-05-22 |
| KR20200035107A (en) | 2020-04-01 |
| WO2019028450A1 (en) | 2019-02-07 |
| CN117987467A (en) | 2024-05-07 |
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