SG11202000556TA - Anti-candida albicans piperazine derivative, preparation method therefor and application thereof - Google Patents

Anti-candida albicans piperazine derivative, preparation method therefor and application thereof

Info

Publication number
SG11202000556TA
SG11202000556TA SG11202000556TA SG11202000556TA SG11202000556TA SG 11202000556T A SG11202000556T A SG 11202000556TA SG 11202000556T A SG11202000556T A SG 11202000556TA SG 11202000556T A SG11202000556T A SG 11202000556TA SG 11202000556T A SG11202000556T A SG 11202000556TA
Authority
SG
Singapore
Prior art keywords
preparation
application
method therefor
candida albicans
piperazine derivative
Prior art date
Application number
SG11202000556TA
Other languages
English (en)
Inventor
Yinyue Deng
Junjun Huang
Xiaorong Huang
Qiumian Ye
Fei He
Shuo Zhao
Yutong Huang
Original Assignee
Univ South China Agricult
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ South China Agricult filed Critical Univ South China Agricult
Publication of SG11202000556TA publication Critical patent/SG11202000556TA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11202000556TA 2017-07-26 2017-07-26 Anti-candida albicans piperazine derivative, preparation method therefor and application thereof SG11202000556TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2017/094458 WO2019019049A1 (zh) 2017-07-26 2017-07-26 一种抗白色念珠菌的哌嗪类衍生物及其制备方法与应用

Publications (1)

Publication Number Publication Date
SG11202000556TA true SG11202000556TA (en) 2020-02-27

Family

ID=65039262

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202000556TA SG11202000556TA (en) 2017-07-26 2017-07-26 Anti-candida albicans piperazine derivative, preparation method therefor and application thereof

Country Status (3)

Country Link
CN (1) CN109496211B (zh)
SG (1) SG11202000556TA (zh)
WO (1) WO2019019049A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102093409B1 (ko) * 2019-10-23 2020-03-25 고려대학교 산학협력단 카바졸 화합물을 유효성분으로 포함하는 항진균 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006300877A1 (en) * 2005-10-13 2007-04-19 Orchid Research Laboratories Limited Heterocyclic compounds as pSTAT3/IL-6 inhibitors
CN102190613B (zh) * 2010-03-14 2014-06-25 浙江华海药业股份有限公司 一种卡维地洛的制备方法
CN102285910B (zh) * 2011-07-04 2013-06-19 南京工业大学 一种制备(s)-卡维地洛的方法
WO2015031914A1 (en) * 2013-08-30 2015-03-05 Uti Limited Partnership Store overload-induced calcium release inhibitors and methods for producing and using the same

Also Published As

Publication number Publication date
WO2019019049A1 (zh) 2019-01-31
CN109496211A (zh) 2019-03-19
CN109496211B (zh) 2022-03-22

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