SG11202000247SA - Neoantigen vaccine composition for treatment of cancer - Google Patents

Neoantigen vaccine composition for treatment of cancer

Info

Publication number
SG11202000247SA
SG11202000247SA SG11202000247SA SG11202000247SA SG11202000247SA SG 11202000247S A SG11202000247S A SG 11202000247SA SG 11202000247S A SG11202000247S A SG 11202000247SA SG 11202000247S A SG11202000247S A SG 11202000247SA SG 11202000247S A SG11202000247S A SG 11202000247SA
Authority
SG
Singapore
Prior art keywords
cancer
treatment
vaccine composition
neoantigen vaccine
neoantigen
Prior art date
Application number
SG11202000247SA
Inventor
Alfredo Nicosia
Elisa Scarselli
Anna Morena D'alise
Original Assignee
Nouscom Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nouscom Ag filed Critical Nouscom Ag
Publication of SG11202000247SA publication Critical patent/SG11202000247SA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/605MHC molecules or ligands thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10041Use of virus, viral particle or viral elements as a vector
    • C12N2710/10043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
SG11202000247SA 2017-07-12 2018-07-12 Neoantigen vaccine composition for treatment of cancer SG11202000247SA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17181026 2017-07-12
EP17200036 2017-11-03
PCT/EP2018/069047 WO2019012091A1 (en) 2017-07-12 2018-07-12 Neoantigen vaccine composition for treatment of cancer

Publications (1)

Publication Number Publication Date
SG11202000247SA true SG11202000247SA (en) 2020-02-27

Family

ID=62904488

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202000247SA SG11202000247SA (en) 2017-07-12 2018-07-12 Neoantigen vaccine composition for treatment of cancer

Country Status (12)

Country Link
US (1) US20200230220A1 (en)
EP (1) EP3651798A1 (en)
JP (1) JP7298926B2 (en)
KR (1) KR20200027499A (en)
CN (1) CN111093699A (en)
AU (1) AU2018300051A1 (en)
BR (1) BR112020000581A2 (en)
CA (1) CA3069051A1 (en)
IL (1) IL271965B2 (en)
MX (1) MX2020000414A (en)
SG (1) SG11202000247SA (en)
WO (1) WO2019012091A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3703744A1 (en) * 2017-11-03 2020-09-09 Nouscom AG Vaccine t cell enhancer
TW202043256A (en) 2019-01-10 2020-12-01 美商健生生物科技公司 Prostate neoantigens and their uses
CN113181351A (en) * 2021-04-28 2021-07-30 广州赛佰澳生物医药科技有限公司 Individual tumor therapeutic vaccine and preparation method thereof
WO2022242652A1 (en) * 2021-05-18 2022-11-24 Hung, Mien-Chie Vaccine, use thereof and cancer vaccine cocktail

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030170850A1 (en) * 2002-03-09 2003-09-11 Cardone Michael H. Cell-based screening methods
ATE449105T1 (en) 2004-01-23 2009-12-15 Angeletti P Ist Richerche Bio CHIMPANZEE ADENOVIRUS VACCINE CARRIAGE
PT1957528E (en) * 2005-11-30 2013-01-09 Univ Copenhagen A nucleotide vaccine
BRPI0921927B8 (en) 2008-11-21 2021-08-31 Koebenhavns Univ University Of Copenhagen Sensitization of an immune response
CN101481675B (en) * 2009-01-06 2011-09-14 武汉大学 Anti-swine fever multi-epitope DNA vaccine, construction method and use
ES2898235T3 (en) 2009-02-02 2022-03-04 Glaxosmithkline Biologicals Sa Simian adenovirus nucleic acid and amino acid sequences, vectors containing them, and their uses
WO2012143499A2 (en) * 2011-04-21 2012-10-26 Bayer Intellectual Property Gmbh Novel binder-drug conjugates (adcs) and their use
BR112013029834A8 (en) 2011-05-24 2022-10-18 Biontech Ag individualized cancer vaccines
WO2014139587A1 (en) * 2013-03-15 2014-09-18 Okairòs Ag Improved poxviral vaccines
CN103623396B (en) * 2013-04-07 2016-03-02 安源生物科技(上海)有限公司 Comprise the pharmaceutical composition of rt-PA
EP3328394A4 (en) * 2015-07-30 2019-03-13 ModernaTX, Inc. Concatemeric peptide epitope rnas
CA3000313A1 (en) 2015-10-08 2017-04-13 The Governors Of The University Of Alberta Hepatitis c virus e1/e2 heterodimers and methods of producing same
WO2017118702A1 (en) * 2016-01-08 2017-07-13 Vaccibody As Neoepitope rna cancer vaccine

Also Published As

Publication number Publication date
EP3651798A1 (en) 2020-05-20
IL271965A (en) 2020-02-27
NZ759944A (en) 2023-08-25
JP7298926B2 (en) 2023-06-27
RU2019144531A3 (en) 2021-08-12
JP2020532287A (en) 2020-11-12
RU2019144531A (en) 2021-08-12
MX2020000414A (en) 2020-09-28
AU2018300051A1 (en) 2020-01-02
IL271965B2 (en) 2023-03-01
CN111093699A (en) 2020-05-01
US20200230220A1 (en) 2020-07-23
CA3069051A1 (en) 2019-01-17
KR20200027499A (en) 2020-03-12
IL271965B (en) 2022-11-01
WO2019012091A1 (en) 2019-01-17
BR112020000581A2 (en) 2020-07-14

Similar Documents

Publication Publication Date Title
IL258955A (en) Compositions and methods for treatment of cancer
IL268814A (en) Compositions and methods for treatment of cancer
PL3622953T3 (en) Combination treatment of cancer
IL285077A (en) Compounds for treatment of cancer
HK1247931A1 (en) Compositions and methods for diagnosis and treatment of cancer
HK1251009B (en) Therapeutic compositions of use for treating cancer
IL271965A (en) Neoantigen vaccine composition for treatment of cancer
IL263793A (en) Compounds and compositions for the treatment of cancer
IL263835A (en) Exosome-guided treatment of cancer
IL261278A (en) Pharmaceutical compositions for the treatment of cancer
ZA201801022B (en) Syd985 treatment of t-dm1 refractory cancer patients
IL274748A (en) Improved treatment of cancer
IL255167A0 (en) Compositions for the treatment of cancer
HK1259029A1 (en) Compositions having anti-fugetactic properties for treatment of cancer
GB201819943D0 (en) Immunotherapeutic treatment of cancer
GB201704287D0 (en) Treatment of cancer
GB201703857D0 (en) Treatment of cancer
GB201702565D0 (en) Treatment of cancer
GB201704474D0 (en) Combination therapy for treatment of cancer
GB201622214D0 (en) treatment of cancer
GB201702139D0 (en) Methods of cancer treatment
GB201604621D0 (en) Treatment of cancer
GB201604293D0 (en) Treatment of cancer
IL236381A0 (en) Pharmaceutical compositions for treatment of cancer
GB201512723D0 (en) Treatment of cancer