SG11202000224SA - An immunogenic composition having improved stability, enhanced immunogenicity and reduced reactogenicity and process for preparation thereof - Google Patents

An immunogenic composition having improved stability, enhanced immunogenicity and reduced reactogenicity and process for preparation thereof

Info

Publication number
SG11202000224SA
SG11202000224SA SG11202000224SA SG11202000224SA SG11202000224SA SG 11202000224S A SG11202000224S A SG 11202000224SA SG 11202000224S A SG11202000224S A SG 11202000224SA SG 11202000224S A SG11202000224S A SG 11202000224SA SG 11202000224S A SG11202000224S A SG 11202000224SA
Authority
SG
Singapore
Prior art keywords
preparation
immunogenic composition
improved stability
enhanced immunogenicity
reduced reactogenicity
Prior art date
Application number
SG11202000224SA
Inventor
Kumar Rakesh
Inder Jit Sharma
Anil Vyankatrao Shitole
Manohar Doddapaneni
Hitt Jyoti Sharma
Original Assignee
Serum Inst Of India Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serum Inst Of India Pvt Ltd filed Critical Serum Inst Of India Pvt Ltd
Publication of SG11202000224SA publication Critical patent/SG11202000224SA/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0016Combination vaccines based on diphtheria-tetanus-pertussis
    • A61K39/0018Combination vaccines based on acellular diphtheria-tetanus-pertussis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/05Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/08Clostridium, e.g. Clostridium tetani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/099Bordetella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/125Picornaviridae, e.g. calicivirus
    • A61K39/13Poliovirus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32611Poliovirus
    • C12N2770/32634Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
SG11202000224SA 2017-07-18 2018-07-13 An immunogenic composition having improved stability, enhanced immunogenicity and reduced reactogenicity and process for preparation thereof SG11202000224SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201721025513 2017-07-18
PCT/IB2018/055180 WO2019016654A1 (en) 2017-07-18 2018-07-13 An immunogenic composition having improved stability, enhanced immunogenicity and reduced reactogenicity and process for preparation thereof

Publications (1)

Publication Number Publication Date
SG11202000224SA true SG11202000224SA (en) 2020-02-27

Family

ID=63556364

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202000224SA SG11202000224SA (en) 2017-07-18 2018-07-13 An immunogenic composition having improved stability, enhanced immunogenicity and reduced reactogenicity and process for preparation thereof

Country Status (19)

Country Link
US (1) US11179453B2 (en)
EP (1) EP3655024A1 (en)
JP (1) JP7404226B2 (en)
CN (1) CN111032078A (en)
AU (1) AU2018302767A1 (en)
BR (1) BR112020000999A2 (en)
CA (1) CA3070039A1 (en)
CO (1) CO2020001765A2 (en)
EA (1) EA202090316A1 (en)
GE (1) GEP20227386B (en)
JO (1) JOP20180069B1 (en)
MX (1) MX2020000441A (en)
PE (1) PE20201443A1 (en)
PH (1) PH12020500133A1 (en)
SG (1) SG11202000224SA (en)
TW (1) TWI786153B (en)
UY (1) UY37811A (en)
WO (1) WO2019016654A1 (en)
ZA (1) ZA202000889B (en)

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SI1896065T2 (en) * 2005-06-27 2014-12-31 Glaxosmithkline Biologicals S.A. Process for manufacturing vaccines
EP3045529B1 (en) 2006-03-10 2020-07-29 Institut Pasteur De Lille Live attenuated bordetella strains as a single dose vaccine against whooping cough
ES2535412T3 (en) 2009-04-28 2015-05-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Vaccine for the prophylaxis or treatment of an airway pathology caused by an allergen
EP3697439A1 (en) * 2017-10-18 2020-08-26 Institut Pasteur de Lille Bordetella strains expressing serotype 3 fimbriae
JOP20190242A1 (en) * 2018-10-12 2020-04-12 Serum Institute Of India Pvt Ltd Combination vaccine composition comprising reduced dose inactivated poliovirus and method for preparing the same
WO2020165920A1 (en) * 2019-02-12 2020-08-20 Biological E Limited Multivalent vaccine composition
CN112138155B (en) * 2019-06-28 2022-04-12 怡道生物科技(苏州)有限公司 Compound adjuvant system and method for preparing adjuvant
JOP20200214A1 (en) 2019-09-03 2021-03-03 Serum Institute Of India Pvt Ltd Immunogenic compositions against enteric diseases and methods for its preparation thereof
EP3988288A1 (en) 2020-10-23 2022-04-27 Carl Zeiss Vision International GmbH Method of manufacturing a spectacle lens
EP3988290A1 (en) 2020-10-23 2022-04-27 Carl Zeiss Vision International GmbH Method for manufacturing a spectacle lens
EP3988289A1 (en) 2020-10-23 2022-04-27 Carl Zeiss Vision International GmbH Method of manufacturing a spectacle lens

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EP0835663B1 (en) 1992-05-23 2009-09-30 GlaxoSmithKline Biologicals S.A. Combined vaccines comprising Hepatitis B surface antigen and other antigens
PT1082965E (en) 1995-06-23 2009-07-01 Glaxosmithkline Biolog Sa A vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminium phosphate
AU4707097A (en) 1997-09-15 1999-04-05 Pasteur Merieux Serums Et Vaccins Multivalent vaccines
GB9806456D0 (en) 1998-03-25 1998-05-27 Smithkline Beecham Biolog Vaccine composition
EP1004314A1 (en) 1998-11-26 2000-05-31 Pasteur Merieux MSD T.d. Polio booster vaccine for a primovaccinated or sensibilisated population
UA79735C2 (en) 2000-08-10 2007-07-25 Глаксосмітклайн Байолоджікалз С.А. Purification of hbv antigens for use in vaccines
GB0313916D0 (en) * 2003-06-16 2003-07-23 Glaxosmithkline Biolog Sa Vaccine composition
GB0405787D0 (en) 2004-03-15 2004-04-21 Chiron Srl Low dose vaccines
GB0616226D0 (en) 2006-08-15 2006-09-27 Novartis Ag Processes
CA2662051A1 (en) * 2006-09-07 2008-03-13 Glaxosmithkline Biologicals S.A. Vaccine
PE20100365A1 (en) * 2008-10-24 2010-05-21 Panacea Biotec Ltd NEW COMBINATION VACCINES WITH WHOLE CELL COUGH AND METHOD FOR THEIR PREPARATION
PE20100366A1 (en) 2008-10-24 2010-05-21 Panacea Biotec Ltd NOVEL COMPOSITIONS OF VACCINE WITH CELLULAR WHOOUS COUGH AS WELL AS THE METHOD FOR ITS ELABORATION
US10092640B2 (en) * 2011-01-05 2018-10-09 Bharat Biotech International Limited Combination heptavalent vaccine
US20160193322A1 (en) * 2013-08-05 2016-07-07 Glaxosmithkline Biologicals S.A. Combination immunogenic compositions
TN2018000063A1 (en) * 2015-09-16 2019-07-08 Lg Chemical Ltd Combination vaccine composition for multiple-dosage.

Also Published As

Publication number Publication date
EP3655024A1 (en) 2020-05-27
UY37811A (en) 2019-01-02
GEP20227386B (en) 2022-06-10
US20200206331A1 (en) 2020-07-02
WO2019016654A1 (en) 2019-01-24
CN111032078A (en) 2020-04-17
BR112020000999A2 (en) 2020-07-14
AU2018302767A1 (en) 2020-03-05
TW201919690A (en) 2019-06-01
JP7404226B2 (en) 2023-12-25
MX2020000441A (en) 2020-08-17
ZA202000889B (en) 2021-06-30
JOP20180069B1 (en) 2022-09-15
JP2020527571A (en) 2020-09-10
EA202090316A1 (en) 2020-12-08
PE20201443A1 (en) 2020-12-10
PH12020500133A1 (en) 2021-02-08
KR20200042470A (en) 2020-04-23
CO2020001765A2 (en) 2020-05-29
TWI786153B (en) 2022-12-11
JOP20180069A1 (en) 2019-01-18
US11179453B2 (en) 2021-11-23
CA3070039A1 (en) 2019-01-24

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