SG11202000007PA - Compositions and methods for treating or preventing catecholaminergic polymorphic ventricular tachycardia - Google Patents

Compositions and methods for treating or preventing catecholaminergic polymorphic ventricular tachycardia

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Publication number
SG11202000007PA
SG11202000007PA SG11202000007PA SG11202000007PA SG11202000007PA SG 11202000007P A SG11202000007P A SG 11202000007PA SG 11202000007P A SG11202000007P A SG 11202000007PA SG 11202000007P A SG11202000007P A SG 11202000007PA SG 11202000007P A SG11202000007P A SG 11202000007PA
Authority
SG
Singapore
Prior art keywords
compositions
treating
preventing
methods
ventricular tachycardia
Prior art date
Application number
SG11202000007PA
Inventor
William Pu
Vassilios Bezzerides
Donghui Zhang
Original Assignee
Childrens Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Medical Center filed Critical Childrens Medical Center
Publication of SG11202000007PA publication Critical patent/SG11202000007PA/en

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
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    • G01N33/5073—Stem cells
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SG11202000007PA 2017-07-06 2018-07-06 Compositions and methods for treating or preventing catecholaminergic polymorphic ventricular tachycardia SG11202000007PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762529256P 2017-07-06 2017-07-06
PCT/US2018/041043 WO2019010386A1 (en) 2017-07-06 2018-07-06 Compositions and methods for treating or preventing catecholaminergic polymorphic ventricular tachycardia

Publications (1)

Publication Number Publication Date
SG11202000007PA true SG11202000007PA (en) 2020-01-30

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ID=64950369

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SG11202000007PA SG11202000007PA (en) 2017-07-06 2018-07-06 Compositions and methods for treating or preventing catecholaminergic polymorphic ventricular tachycardia

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Country Link
US (1) US20210147497A1 (en)
EP (1) EP3648755A4 (en)
JP (1) JP2020532492A (en)
KR (1) KR20200027521A (en)
CN (1) CN111194212A (en)
AU (1) AU2018297171A1 (en)
BR (1) BR112020000258A2 (en)
CA (1) CA3069127A1 (en)
CO (1) CO2020005617A2 (en)
EA (1) EA202090231A1 (en)
IL (1) IL271823A (en)
MX (1) MX2020000090A (en)
SG (1) SG11202000007PA (en)
WO (1) WO2019010386A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114105916B (en) * 2021-11-25 2023-04-18 深圳大学 RyR2 stabilizer, preparation method thereof, corresponding medicinal composition and application

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040048780A1 (en) * 2000-05-10 2004-03-11 The Trustees Of Columbia University In The City Of New York Method for treating and preventing cardiac arrhythmia
US7704990B2 (en) * 2005-08-25 2010-04-27 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US8816046B2 (en) * 2007-09-26 2014-08-26 The University Of Colorado, A Body Corporate Compositions and methods for CaMKII inhibitors and uses thereof
SG192305A1 (en) * 2012-01-20 2013-08-30 Singapore Health Serv Pte Ltd Induced pluripotent stem cell (ipsc)-derived cardiomyocyte-like cells and uses thereof in screening for agents
CA2901155C (en) * 2013-03-06 2021-06-08 Allosteros Therapeutics, Inc. Camkii inhibitors and uses thereof
WO2016168694A1 (en) * 2015-04-15 2016-10-20 Ohio State Innovation Foundation Engineered calmodulin for treatment of ryanopathies

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CO2020005617A2 (en) 2020-07-31
KR20200027521A (en) 2020-03-12
US20210147497A1 (en) 2021-05-20
MX2020000090A (en) 2020-08-06
BR112020000258A2 (en) 2020-07-14
AU2018297171A1 (en) 2020-01-30
CA3069127A1 (en) 2019-01-10
JP2020532492A (en) 2020-11-12
IL271823A (en) 2020-02-27
WO2019010386A1 (en) 2019-01-10
EP3648755A4 (en) 2021-10-20
CN111194212A (en) 2020-05-22
EA202090231A1 (en) 2020-06-08
EP3648755A1 (en) 2020-05-13

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