SG11201913244QA - Therapeutic combination of a third generation egfr tyrosine kinase inhibitor and a cyclin d kinase inhibitor - Google Patents
Therapeutic combination of a third generation egfr tyrosine kinase inhibitor and a cyclin d kinase inhibitorInfo
- Publication number
- SG11201913244QA SG11201913244QA SG11201913244QA SG11201913244QA SG11201913244QA SG 11201913244Q A SG11201913244Q A SG 11201913244QA SG 11201913244Q A SG11201913244Q A SG 11201913244QA SG 11201913244Q A SG11201913244Q A SG 11201913244QA SG 11201913244Q A SG11201913244Q A SG 11201913244QA
- Authority
- SG
- Singapore
- Prior art keywords
- kinase inhibitor
- cyclin
- therapeutic combination
- egfr tyrosine
- generation egfr
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762540594P | 2017-08-03 | 2017-08-03 | |
| PCT/IB2018/055791 WO2019026006A1 (en) | 2017-08-03 | 2018-08-01 | Therapeutic combination of a third generation egfr tyrosine kinase inhibitor and a cyclin d kinase inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201913244QA true SG11201913244QA (en) | 2020-02-27 |
Family
ID=63405288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201913244QA SG11201913244QA (en) | 2017-08-03 | 2018-08-01 | Therapeutic combination of a third generation egfr tyrosine kinase inhibitor and a cyclin d kinase inhibitor |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20200155566A1 (en) |
| EP (1) | EP3661519A1 (en) |
| JP (1) | JP2020529423A (en) |
| KR (1) | KR20200036879A (en) |
| CN (1) | CN110996962A (en) |
| AU (1) | AU2018311522A1 (en) |
| BR (1) | BR112020001821A2 (en) |
| CA (1) | CA3069561A1 (en) |
| CL (1) | CL2020000271A1 (en) |
| IL (1) | IL272369A (en) |
| JO (1) | JOP20200015A1 (en) |
| MX (1) | MX2020001253A (en) |
| PH (1) | PH12020500099A1 (en) |
| RU (1) | RU2020108191A (en) |
| SG (1) | SG11201913244QA (en) |
| TW (1) | TW201909921A (en) |
| WO (1) | WO2019026006A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3738084A4 (en) | 2018-01-08 | 2021-11-17 | G1 Therapeutics, Inc. | G1t38 superior dosage regimes |
| TW202114689A (en) * | 2019-08-06 | 2021-04-16 | 大陸商江蘇恒瑞醫藥股份有限公司 | Use of combination of cdk4/6 inhibitor and multi-target tyrosine kinase inhibitor in preparation of medicine for treating tumor |
| EP4171556A1 (en) * | 2020-06-25 | 2023-05-03 | Tolremo Therapeutics AG | A combination of a cbp/p300 bromodomain inhibitor and an egfr inhibitor for use in treating egfr-mutant nsclc |
| CN113628682B (en) * | 2021-08-11 | 2023-10-24 | 上海小海龟科技有限公司 | T790M and C797S cis-trans mutation type identification and calculation method |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101353857B1 (en) | 2008-08-22 | 2014-01-21 | 노파르티스 아게 | Pyrrolopyrimidine compounds as cdk inhibitors |
| JO3300B1 (en) | 2012-06-06 | 2018-09-16 | Novartis Ag | Compounds and compositions for modulating egfr activity |
| AU2014307633A1 (en) * | 2013-08-14 | 2016-02-11 | Novartis Ag | Combination therapy for the treatment of cancer |
| JP2018526376A (en) * | 2015-08-28 | 2018-09-13 | ノバルティス アーゲー | Includes (A) the cyclin-dependent kinase 4/6 (CDK4 / 6) inhibitor LEE011 (= ribocyclib) and (B) the epidermal growth factor receptor (EGFR) inhibitor erlotinib for the treatment or prevention of cancer Pharmaceutical combination |
| WO2018156812A1 (en) * | 2017-02-22 | 2018-08-30 | G1 Therapeutics, Inc. | Treatment of egfr-driven cancer with fewer side effects |
-
2018
- 2018-08-01 JP JP2020505467A patent/JP2020529423A/en active Pending
- 2018-08-01 AU AU2018311522A patent/AU2018311522A1/en not_active Abandoned
- 2018-08-01 CN CN201880050149.7A patent/CN110996962A/en active Pending
- 2018-08-01 MX MX2020001253A patent/MX2020001253A/en unknown
- 2018-08-01 US US16/632,954 patent/US20200155566A1/en not_active Abandoned
- 2018-08-01 SG SG11201913244QA patent/SG11201913244QA/en unknown
- 2018-08-01 KR KR1020207004657A patent/KR20200036879A/en unknown
- 2018-08-01 WO PCT/IB2018/055791 patent/WO2019026006A1/en active Application Filing
- 2018-08-01 CA CA3069561A patent/CA3069561A1/en not_active Abandoned
- 2018-08-01 BR BR112020001821-0A patent/BR112020001821A2/en not_active Application Discontinuation
- 2018-08-01 EP EP18760055.6A patent/EP3661519A1/en not_active Withdrawn
- 2018-08-01 RU RU2020108191A patent/RU2020108191A/en not_active Application Discontinuation
- 2018-08-01 JO JOP/2020/0015A patent/JOP20200015A1/en unknown
- 2018-08-03 TW TW107127152A patent/TW201909921A/en unknown
-
2020
- 2020-01-14 PH PH12020500099A patent/PH12020500099A1/en unknown
- 2020-01-30 CL CL2020000271A patent/CL2020000271A1/en unknown
- 2020-01-30 IL IL272369A patent/IL272369A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2020108191A (en) | 2021-09-03 |
| MX2020001253A (en) | 2020-07-13 |
| CL2020000271A1 (en) | 2020-08-28 |
| US20200155566A1 (en) | 2020-05-21 |
| AU2018311522A1 (en) | 2020-01-16 |
| PH12020500099A1 (en) | 2020-09-14 |
| BR112020001821A2 (en) | 2020-07-21 |
| TW201909921A (en) | 2019-03-16 |
| JOP20200015A1 (en) | 2022-10-30 |
| JP2020529423A (en) | 2020-10-08 |
| KR20200036879A (en) | 2020-04-07 |
| CN110996962A (en) | 2020-04-10 |
| CA3069561A1 (en) | 2019-02-07 |
| IL272369A (en) | 2020-03-31 |
| EP3661519A1 (en) | 2020-06-10 |
| WO2019026006A1 (en) | 2019-02-07 |
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