SG11201901473UA - Hydrophilic copolymer and medical device - Google Patents

Hydrophilic copolymer and medical device

Info

Publication number
SG11201901473UA
SG11201901473UA SG11201901473UA SG11201901473UA SG11201901473UA SG 11201901473U A SG11201901473U A SG 11201901473UA SG 11201901473U A SG11201901473U A SG 11201901473UA SG 11201901473U A SG11201901473U A SG 11201901473UA SG 11201901473U A SG11201901473U A SG 11201901473UA
Authority
SG
Singapore
Prior art keywords
hydrophilic copolymer
group
polymerizable monomer
structural units
units derived
Prior art date
Application number
SG11201901473UA
Inventor
Masanori Kuramoto
Takao Anzai
Original Assignee
Terumo Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo Corp filed Critical Terumo Corp
Publication of SG11201901473UA publication Critical patent/SG11201901473UA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/58—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing oxygen in addition to the carbonamido oxygen, e.g. N-methylolacrylamide, N-(meth)acryloylmorpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/38—Esters containing sulfur
    • C08F220/387—Esters containing sulfur and containing nitrogen and oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/58—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing oxygen in addition to the carbonamido oxygen, e.g. N-methylolacrylamide, N-(meth)acryloylmorpholine
    • C08F220/585—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing oxygen in addition to the carbonamido oxygen, e.g. N-methylolacrylamide, N-(meth)acryloylmorpholine and containing other heteroatoms, e.g. 2-acrylamido-2-methylpropane sulfonic acid [AMPS]
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D133/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
    • C09D133/04—Homopolymers or copolymers of esters
    • C09D133/14—Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur or oxygen atoms in addition to the carboxy oxygen
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M107/00—Lubricating compositions characterised by the base-material being a macromolecular compound
    • C10M107/46—Lubricating compositions characterised by the base-material being a macromolecular compound containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M107/00—Lubricating compositions characterised by the base-material being a macromolecular compound
    • C10M107/48—Lubricating compositions characterised by the base-material being a macromolecular compound containing phosphorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/10—Materials for lubricating medical devices
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/38—Esters containing sulfur
    • C08F220/382—Esters containing sulfur and containing oxygen, e.g. 2-sulfoethyl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00—Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/10—Copolymer characterised by the proportions of the comonomers expressed as molar percentages
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M2221/00—Organic macromolecular compounds containing sulfur, selenium or tellurium as ingredients in lubricant compositions
    • C10M2221/02—Macromolecular compounds obtained by reactions of monomers involving only carbon-to-carbon unsaturated bonds
    • C10M2221/025—Macromolecular compounds obtained by reactions of monomers involving only carbon-to-carbon unsaturated bonds used as base material
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M2225/00—Organic macromolecular compounds containing phosphorus as ingredients in lubricant compositions
    • C10M2225/02—Macromolecular compounds from phosphorus-containg monomers, obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • C10M2225/025—Macromolecular compounds from phosphorus-containg monomers, obtained by reactions involving only carbon-to-carbon unsaturated bonds used as base material
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10N—INDEXING SCHEME ASSOCIATED WITH SUBCLASS C10M RELATING TO LUBRICATING COMPOSITIONS
    • C10N2040/00—Specified use or application for which the lubricating composition is intended
    • C10N2040/50—Medical uses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)

Abstract

HYDROPHILIC COPOLYMER AND MEDICAL DEVICE [Problem] To provide a hydrophilic copolymer that can form a surface lubricious layer exhibiting superior lubricating property and durability (lubrication retaining property). To also provide a hydrophilic copolymer having a good solvent solubility. [Means for Resolution] A hydrophilic copolymer containing: structural units derived from a polymerizable monomer (A) having a sulfobetaine structure; structural units derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (-SO3H), a sulfuric acid group (-OSO3H), a sulfurous acid group (-OSO2H), and groups of salts thereof; and structural units derived from a polymerizable monomer (C) having a photoreactive group.
SG11201901473UA 2016-08-25 2017-08-21 Hydrophilic copolymer and medical device SG11201901473UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016164815 2016-08-25
PCT/JP2017/029825 WO2018038063A1 (en) 2016-08-25 2017-08-21 Hydrophilic copolymer and medical device

Publications (1)

Publication Number Publication Date
SG11201901473UA true SG11201901473UA (en) 2019-03-28

Family

ID=61244889

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201901473UA SG11201901473UA (en) 2016-08-25 2017-08-21 Hydrophilic copolymer and medical device

Country Status (9)

Country Link
US (1) US11377512B2 (en)
EP (1) EP3505543B1 (en)
JP (2) JP7001602B2 (en)
CN (1) CN109641994B (en)
AU (1) AU2017317423B2 (en)
BR (1) BR112019001648B1 (en)
ES (1) ES2886838T3 (en)
SG (1) SG11201901473UA (en)
WO (1) WO2018038063A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2958666A4 (en) 2013-02-21 2016-11-23 Univ California Universal scalable and cost-effective surface modifications
EP3505543B1 (en) * 2016-08-25 2021-07-28 Terumo Kabushiki Kaisha Hydrophilic copolymer and medical device
KR20230026540A (en) 2016-12-01 2023-02-24 더 리전트 오브 더 유니버시티 오브 캘리포니아 Energy providing devices and application thereof
SG11202004599WA (en) * 2017-12-01 2020-06-29 Univ California Biofouling resistant coatings and methods of making and using the same
JP7267988B2 (en) * 2018-02-20 2023-05-02 テルモ株式会社 medical equipment
JP7252225B2 (en) * 2018-06-27 2023-04-04 テルモ株式会社 Hydrophilic copolymers and medical devices
MX2021011113A (en) * 2019-03-14 2021-10-13 Univ Washington Zwitterionic copolymer coatings and related methods.
JP2022535416A (en) 2019-06-05 2022-08-08 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Biofouling resistant coatings and methods of making and using the same
WO2021033765A1 (en) 2019-08-21 2021-02-25 テルモ株式会社 Medical instrument and method for manufacturing same
EP4006069A4 (en) * 2019-08-21 2022-09-14 TERUMO Kabushiki Kaisha Medical instrument and production method therefor
JP7541522B2 (en) * 2019-08-21 2024-08-28 テルモ株式会社 Medical device and its manufacturing method
EP4006068A4 (en) * 2019-08-21 2022-09-14 TERUMO Kabushiki Kaisha Medical instrument and manufacturing method therefor
WO2021033763A1 (en) 2019-08-21 2021-02-25 テルモ株式会社 Medical instrument and method for manufacturing same
JP2024057623A (en) * 2021-03-12 2024-04-25 テルモ株式会社 Medical device
JP2024060627A (en) * 2021-03-22 2024-05-07 テルモ株式会社 Hydrophilic copolymer and medical instrument
WO2024009927A1 (en) * 2022-07-07 2024-01-11 テルモ株式会社 Indwelling catheter

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0757806B2 (en) * 1987-04-16 1995-06-21 日本ペイント株式会社 Colored fine resin particles and manufacturing method thereof
JPH05237377A (en) * 1992-02-24 1993-09-17 Toagosei Chem Ind Co Ltd Ion sequestering agent, water absorbing resin and method for water absorption
JP3587267B2 (en) * 1994-10-07 2004-11-10 東洋紡績株式会社 Salt-resistant latex
US5702754A (en) 1995-02-22 1997-12-30 Meadox Medicals, Inc. Method of providing a substrate with a hydrophilic coating and substrates, particularly medical devices, provided with such coatings
JP2001139640A (en) * 1999-11-12 2001-05-22 Mitsubishi Chemicals Corp Uv-absorbing copolymer
WO2002040558A1 (en) * 2000-11-16 2002-05-23 Biocompatibles Uk Limited Polymers and polymerisation processes
US7645504B1 (en) 2003-06-26 2010-01-12 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices comprising hydrophobic and hydrophilic polymers
JP5557373B2 (en) * 2006-11-21 2014-07-23 アボット ラボラトリーズ Use of terpolymers of tetrafluoroethylene, hexafluoropropylene, and vinylidene fluoride in drug-eluting coatings
WO2009099126A1 (en) 2008-02-07 2009-08-13 Riken Photoreactive copolymer, surface modifier, hydrophilic treatment agent, adsorption inhibitor, substance-immobilizing agent, surface modification method, hydrophilization method, adsorption inhibition method, and substance-immobilizing method
JP5604154B2 (en) * 2010-04-02 2014-10-08 株式会社メニコン Polymer materials, ophthalmic lenses and contact lenses
TWI520948B (en) 2010-06-30 2016-02-11 Nissan Chemical Ind Ltd A liquid crystal alignment device, a liquid crystal alignment device, a liquid crystal display device, and a liquid crystal display device, and a polymerizable compound
US8541498B2 (en) * 2010-09-08 2013-09-24 Biointeractions Ltd. Lubricious coatings for medical devices
DE102011100430A1 (en) * 2011-05-04 2012-11-08 Polyprec Gmbh New shear-stable polymer systems, their production and their use as thickeners
EP2941279B1 (en) * 2013-01-04 2023-05-17 SurModics, Inc. Low particulate lubricious coating with vinyl pyrrolidone and acidic polymer-containing layers
CN105073155B (en) * 2013-04-01 2018-10-19 泰尔茂株式会社 The manufacturing method of medical instrument and medical instrument
JP6371165B2 (en) * 2014-09-02 2018-08-08 住友ゴム工業株式会社 Metal medical tools
US10342898B2 (en) * 2015-12-29 2019-07-09 Surmodics, Inc. Lubricious coatings with surface salt groups
JP6048612B2 (en) 2016-06-16 2016-12-21 株式会社寺岡精工 POS system and program
EP3505543B1 (en) * 2016-08-25 2021-07-28 Terumo Kabushiki Kaisha Hydrophilic copolymer and medical device

Also Published As

Publication number Publication date
CN109641994A (en) 2019-04-16
AU2017317423A1 (en) 2019-03-07
JP7001602B2 (en) 2022-01-19
JP2022036146A (en) 2022-03-04
EP3505543A1 (en) 2019-07-03
BR112019001648A2 (en) 2019-05-07
CN109641994B (en) 2021-07-09
BR112019001648B1 (en) 2022-09-06
US20190185776A1 (en) 2019-06-20
JP7368446B2 (en) 2023-10-24
WO2018038063A1 (en) 2018-03-01
ES2886838T3 (en) 2021-12-21
EP3505543B1 (en) 2021-07-28
JPWO2018038063A1 (en) 2019-06-20
AU2017317423B2 (en) 2019-08-15
EP3505543A4 (en) 2020-04-15
US11377512B2 (en) 2022-07-05

Similar Documents

Publication Publication Date Title
SG11201901473UA (en) Hydrophilic copolymer and medical device
BR112016028322A2 (en) light curable composition, light curable ink, composition container, image or cured product method, image or cured product, and image or cured product
ES2659525T3 (en) Controlled hydrolysis of poly-4-hydroxybutyrate and copolymers
SG10201808743VA (en) Compositions comprising electrohydrodynamically obtained fibres for administration of specific dosages of an active substance to skin or mucosa
MX2016010843A (en) Aqueous multi-stage copolymer compositions for use in leather topcoats.
MY160125A (en) Aromatic polyether sulfone block copolymers
BR112015004803A2 (en) Method for solvent-free preparation of a (meth) acrylic acid polymer in solution, aqueous (meth) acrylic acid polymers solution, and use thereof
MX2018011806A (en) Lubricious coating for medical device.
EA201691318A1 (en) BLOCK-COPOLYMER AND GLUE COMPOSITION
CL2017003124A1 (en) Positive allosteric modulators of the muscarinic m2 receptor
EP4241797A3 (en) (meth)acrylamide polymers for contact lens and intraocular lens
BR112015010051A2 (en) composition, article, film and method for preparing a movie
BR112016023872A2 (en) Resin composition suitable for printing and printing method using the same
BR112018012806A2 (en) medical device, and method for producing a medical device.
BR112015007888A2 (en) particle manufacturing method, particles and particle manufacturing apparatus
BR112015028414A2 (en) polymer micelle pharmaceutical composition
JP2012199532A5 (en)
NZ727834A (en) Fast acting orally disintegrating film
BR112018073566A2 (en) hydrophobic intraocular lenses
BR112016024102A2 (en) medical device containing anionic drug
BR112018070538A2 (en) distance estimator with multiple markings
WO2015069384A3 (en) High refractive index silicone nanocomposites
TW201614007A (en) Composition for forming silica layer, silica layer, and electronic device
AR099066A1 (en) POLYMERS THAT INCLUDE SULPHONIC ACID GROUPS
BR112016007277A2 (en) Method for polymerizing met (acrylic acid) into a solution, polymer solutions obtained and uses thereof