SG11201810731WA - External preparation for skin for wrinkle improvement - Google Patents

External preparation for skin for wrinkle improvement

Info

Publication number
SG11201810731WA
SG11201810731WA SG11201810731WA SG11201810731WA SG11201810731WA SG 11201810731W A SG11201810731W A SG 11201810731WA SG 11201810731W A SG11201810731W A SG 11201810731WA SG 11201810731W A SG11201810731W A SG 11201810731WA SG 11201810731W A SG11201810731W A SG 11201810731WA
Authority
SG
Singapore
Prior art keywords
skin
linear
external preparation
branched alkyl
alkyl group
Prior art date
Application number
SG11201810731WA
Inventor
Toshihiro Hinokitani
Shigetsugu Homma
Original Assignee
Pola Chem Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pola Chem Ind Inc filed Critical Pola Chem Ind Inc
Publication of SG11201810731WA publication Critical patent/SG11201810731WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • A61K8/025Explicitly spheroidal or spherical shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/042Gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/18Antioxidants, e.g. antiradicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A method for improving dermal retentivity of a compound, which compound is effective for prevention or improvement of skin aging, is provided. The oil-gel- form external preparation for skin containing: 1) a compound represented by the 5 following General Formula (1), an isomer thereof, and/or a pharmaceutically acceptable salt thereof; and 2) a partially cross-linked methyl polysiloxane; of the present invention allows easy penetration of the effective component of 1) from the preparation into the skin while enhancing the percutaneous absorbability and improving the intradermal retentivity. 10 [In the formula, R1 represents a C1-C4 linear or branched alkyl group substituted by a carboxyl group(s), or a C1-C4 linear or branched alkyl group substituted by a carboxylic acid ester group(s) having a C1-C4 alkyl chain, and R2 and R3 each independently represent a C1-C4 linear or branched alkyl group.] 15 EXTERNAL PREPARATION FOR SKIN FOR WRINKLE IMPROVEMENT [No Available Figure]
SG11201810731WA 2016-06-24 2017-06-21 External preparation for skin for wrinkle improvement SG11201810731WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016125685 2016-06-24
PCT/JP2017/022824 WO2017221973A1 (en) 2016-06-24 2017-06-21 External preparation for skin for wrinkle improvement

Publications (1)

Publication Number Publication Date
SG11201810731WA true SG11201810731WA (en) 2019-01-30

Family

ID=60783440

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201810731WA SG11201810731WA (en) 2016-06-24 2017-06-21 External preparation for skin for wrinkle improvement

Country Status (17)

Country Link
US (1) US11413224B2 (en)
EP (2) EP3476381B1 (en)
JP (2) JP6554752B2 (en)
KR (1) KR102431188B1 (en)
CN (2) CN109310585B (en)
AU (1) AU2017282393B2 (en)
BR (1) BR112018073968B1 (en)
CA (1) CA3026270A1 (en)
ES (1) ES2905761T3 (en)
IL (2) IL263275B (en)
MX (1) MX2018014932A (en)
MY (2) MY194060A (en)
RU (1) RU2743039C2 (en)
SG (1) SG11201810731WA (en)
TW (2) TWI734647B (en)
UA (1) UA122923C2 (en)
WO (1) WO2017221973A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL274690B2 (en) * 2017-11-15 2023-12-01 Pola Chem Ind Inc Oil-based composition
JP2019206485A (en) * 2018-05-29 2019-12-05 ポーラ化成工業株式会社 Wrinkle-reducing composition

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3242874A (en) 1963-10-25 1966-03-29 Fisher & Ludlow Ltd Conveyors for conveying goods
JPS492483B1 (en) 1969-01-28 1974-01-21
US5296591A (en) 1990-12-31 1994-03-22 Fujisawa Pharmaceutical Co., Ltd. Trifluoromethylketone derivatives, processes for preparation thereof and use thereof
JP3492483B2 (en) 1996-10-03 2004-02-03 株式会社資生堂 Gel skin external preparation
KR100207078B1 (en) 1996-10-18 1999-07-15 윤종용 A washing machine
JP2002161051A (en) 1996-12-24 2002-06-04 Fujisawa Pharmaceut Co Ltd Therapeutic agent for cerebral ischemic disease or the like
FR2757380B1 (en) 1996-12-24 1999-01-29 Oreal NON-TRANSFER MAKE-UP OR CARE COMPOSITION CONTAINING ORGANOPOLYSILOXANE AND FAT PHASE
KR19990043352A (en) 1997-11-29 1999-06-15 전주범 Monitor brightness adjustment device and method for learning efficiency
US6610748B1 (en) * 1998-02-24 2003-08-26 Fujisawa Pharmaceutical Co., Ltd. Preventives/remedies for skin aging
JP2001040263A (en) 1999-07-29 2001-02-13 Pentel Corp Water-base glossy ink composition
WO2001026685A1 (en) * 1999-10-12 2001-04-19 Fujisawa Pharmaceutical Co., Ltd. Remedies for intractable wound
AU1556601A (en) 1999-12-03 2001-06-12 Ono Pharmaceutical Co. Ltd. 1,3,4-oxadiazolin-2-one derivatives and drugs containing these derivatives as the active ingredient
EP1136064A3 (en) 2000-03-21 2001-10-17 Avon Products, Inc. Method for improving the apperance of skin and topical compositions for practicing the same
JP2002255847A (en) 2001-02-26 2002-09-11 Miyagi Kagaku Kogyo Kk Collagen production promoter, functional food and pharmaceutical preparation
JP2003300851A (en) 2002-04-10 2003-10-21 Pola Chem Ind Inc Fragrance composition
JP4336486B2 (en) 2002-10-04 2009-09-30 一丸ファルコス株式会社 Hyaluronic acid production promoter
FR2856924B1 (en) * 2003-07-02 2008-08-22 Oreal COSMETIC COMPOSITION CONTAINING SILICONE ELASTOMER AND BLOCK SILICONE POLYMER
JP2005041795A (en) 2003-07-24 2005-02-17 P & P F:Kk Oily cosmetic for correcting unevenness of skin
US20090011035A1 (en) * 2007-07-03 2009-01-08 Joseph Michael Zukowski Personal care composition
ES2781401T3 (en) * 2008-11-19 2020-09-01 Pola Chem Ind Inc Anti-wrinkle agents
WO2012124436A1 (en) * 2011-03-17 2012-09-20 株式会社 資生堂 Skin cosmetic
JP6536321B2 (en) * 2014-10-01 2019-07-03 日油株式会社 Oil gel cosmetic

Also Published As

Publication number Publication date
CN109310585B (en) 2021-10-29
JPWO2017221973A1 (en) 2018-06-28
TW201803550A (en) 2018-02-01
KR20190021216A (en) 2019-03-05
EP3476381A1 (en) 2019-05-01
CN113693965A (en) 2021-11-26
US20210030631A1 (en) 2021-02-04
EP3476381B1 (en) 2021-12-22
RU2018142778A3 (en) 2020-10-13
IL263275A (en) 2018-12-31
CN113693965B (en) 2024-03-29
BR112018073968B1 (en) 2022-08-02
CN109310585A (en) 2019-02-05
JP2019048889A (en) 2019-03-28
ES2905761T3 (en) 2022-04-12
BR112018073968A2 (en) 2019-02-26
IL263275B (en) 2021-03-25
US11413224B2 (en) 2022-08-16
IL274153B (en) 2021-12-01
JP7016794B2 (en) 2022-02-07
AU2017282393B2 (en) 2022-06-02
EP4008304A3 (en) 2022-07-20
MY189548A (en) 2022-02-16
AU2017282393A1 (en) 2018-12-13
EP3476381A4 (en) 2020-01-01
EP4008304A2 (en) 2022-06-08
TWI734647B (en) 2021-07-21
WO2017221973A1 (en) 2017-12-28
JP6554752B2 (en) 2019-08-07
CA3026270A1 (en) 2017-12-28
KR102431188B1 (en) 2022-08-10
UA122923C2 (en) 2021-01-20
RU2743039C2 (en) 2021-02-12
MY194060A (en) 2022-11-10
MX2018014932A (en) 2019-04-24
IL274153A (en) 2020-06-30
TWI720214B (en) 2021-03-01
RU2018142778A (en) 2020-07-24
TW202110470A (en) 2021-03-16

Similar Documents

Publication Publication Date Title
ZA202110659B (en) Methods of reducing the risk of cardiovascular events in a subject
WO2016077464A8 (en) Amino acid derivatives and their uses
MX2021009806A (en) Medium chain fatty acid esters of beta-hydroxybutyrate and butanediol and compositions and methods for using same.
PH12016501175B1 (en) Formulations of deoxycholic acid and salts thereof
AU2015275248B2 (en) Legumain activated doxorubicin derivative as well as preparation method and application thereof
MX2013007938A (en) Novel bicyclic compound or salt thereof.
WO2014102592A3 (en) Oxime/substituted quinoxaline-type piperidine compounds and uses thereof
PH12019502868A1 (en) Composition for injection
SG11201810731WA (en) External preparation for skin for wrinkle improvement
MY195881A (en) Griseofulvin Compound
BR112017023144A2 (en) cosmetic compositions comprising stolide esters and uses for hair treatment
RU2012134454A (en) AGENT FOR PREVENTION OR PIGMENTATION REDUCTION
BR112012020703A2 (en) pest control composition
IN2015DN01329A (en)
WO2012142125A3 (en) Plasmodial surface anion channel inhibitors for the treatment or prevention of malaria
MY186194A (en) Pest control composition
MY198008A (en) Crystal of benzofuran derivative free base and preparation method
PH12015500047A1 (en) Pharmaceutical composition for inhibiting autophagy of motor neurons and use thereof
MX2019011558A (en) Novel substituted n'-hydroxycarbamimidoyl-1,2,5-oxadiazole compounds as indoleamine 2,3-dioxygenase (ido) inhibitors.
MY169329A (en) Derivative of butylphthalide and preparation method and use thereof
WO2014118077A3 (en) Reaction accelerator for a copolymerisation, electrical-insulation tape, electrical-insulation body, and consolidation body
PH12020550549A1 (en) Compositions for preventing or treating lupus
PH12018501138A1 (en) Pest control composition including iminopyridine derivative
MX2017016120A (en) Solubilizing agents for functional active compounds.
MX2017005772A (en) Hemiacetyl proflavors.