SG11201809049UA - Enhanced gene delivery methods - Google Patents

Enhanced gene delivery methods

Info

Publication number
SG11201809049UA
SG11201809049UA SG11201809049UA SG11201809049UA SG11201809049UA SG 11201809049U A SG11201809049U A SG 11201809049UA SG 11201809049U A SG11201809049U A SG 11201809049UA SG 11201809049U A SG11201809049U A SG 11201809049UA SG 11201809049U A SG11201809049U A SG 11201809049UA
Authority
SG
Singapore
Prior art keywords
gene delivery
delivery methods
enhanced gene
enhanced
methods
Prior art date
Application number
SG11201809049UA
Inventor
Paul Finnegan
Claude Davis
Michael Ginsberg
Daniel Nolan
Original Assignee
Angiocrine Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angiocrine Bioscience Inc filed Critical Angiocrine Bioscience Inc
Publication of SG11201809049UA publication Critical patent/SG11201809049UA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
SG11201809049UA 2016-04-15 2017-04-17 Enhanced gene delivery methods SG11201809049UA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662323476P 2016-04-15 2016-04-15
US201662403110P 2016-10-01 2016-10-01
PCT/US2017/027884 WO2017181168A1 (en) 2016-04-15 2017-04-17 Enhanced gene delivery methods

Publications (1)

Publication Number Publication Date
SG11201809049UA true SG11201809049UA (en) 2018-11-29

Family

ID=60041985

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201809049UA SG11201809049UA (en) 2016-04-15 2017-04-17 Enhanced gene delivery methods

Country Status (11)

Country Link
US (1) US20190127760A1 (en)
EP (1) EP3442544A4 (en)
JP (1) JP7080184B2 (en)
KR (1) KR102428606B1 (en)
CN (1) CN109475582A (en)
AU (1) AU2017248848B2 (en)
CA (1) CA3021090A1 (en)
IL (1) IL262310B1 (en)
RU (1) RU2018139201A (en)
SG (1) SG11201809049UA (en)
WO (1) WO2017181168A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110121555B (en) 2016-09-13 2023-10-20 安吉克莱茵生物科学有限公司 Blood brain barrier comprising engineered endothelial cells
CN110075319A (en) * 2019-04-29 2019-08-02 白涛 A kind of anti-hereditary disease biological missile
WO2023081277A1 (en) * 2021-11-03 2023-05-11 Memorial Sloan-Kettering Cancer Center Epigenetic targets in clonal hematopoiesis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003014313A2 (en) * 2001-08-06 2003-02-20 Bresagen, Ltd. Alternative compositions and methods for the culture of stem cells
EP1799812A4 (en) * 2004-09-16 2009-09-09 Gamida Cell Ltd Methods of ex vivo progenitor and stem cell expansion by co-culture with mesenchymal cells
WO2008089448A2 (en) 2007-01-19 2008-07-24 Cornell Presearch Foundation, Inc. Methods and compositions for promoting survival & proliferation of endothelial cells & stimulating angiogenesis
CN105051184B (en) * 2013-01-15 2018-08-10 康奈尔大学 It is hematopoiesis multi-lineage progenitor cells to be reprogrammed human endothelial cells by the given factor
PL2970912T3 (en) * 2013-03-13 2019-08-30 Wisconsin Alumni Research Foundation Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditions
KR101772783B1 (en) 2013-03-13 2017-08-29 캐보트 코포레이션 Coatings having filler-polymer compositions with combined low dielectric constant, high resistivity, and optical density properties and controlled electrical resistivity, devices made therewith, and methods for making same
WO2015057976A1 (en) * 2013-10-17 2015-04-23 Sangamo Biosciences, Inc. Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells

Also Published As

Publication number Publication date
IL262310B1 (en) 2024-02-01
EP3442544A4 (en) 2020-01-01
IL262310A (en) 2018-11-29
KR20180133484A (en) 2018-12-14
RU2018139201A3 (en) 2020-11-13
CN109475582A (en) 2019-03-15
RU2018139201A (en) 2020-05-15
CA3021090A1 (en) 2017-10-19
EP3442544A1 (en) 2019-02-20
JP2019511238A (en) 2019-04-25
KR102428606B1 (en) 2022-08-02
US20190127760A1 (en) 2019-05-02
JP7080184B2 (en) 2022-06-03
AU2017248848B2 (en) 2022-12-08
AU2017248848A1 (en) 2018-11-22
WO2017181168A1 (en) 2017-10-19

Similar Documents

Publication Publication Date Title
HK1252836A1 (en) Drug delivery from hydrogels
IL284577A (en) Gene therapy
ZA201604874B (en) Rna-guided gene drives
HK1252168A1 (en) Genetic construct
HK1249034A1 (en) Delivery vehicle
GB201407322D0 (en) Gene therapy
HK1250370A1 (en) Bortezomib-based delivery system
IL249254B (en) Gene expression system
IL257500A (en) Modified cullin1 gene
IL262310A (en) Enhanced gene delivery methods
PT3126521T (en) Hnf4g-rspo2 fusion gene
GB201705955D0 (en) Delivery method
GB201513151D0 (en) Functional gene replacement therapy
IL263085A (en) Gene therapy
GB201507125D0 (en) Gene delivery
GB201616821D0 (en) Gene therapy
GB201612104D0 (en) Gene therapy
GB201612105D0 (en) Gene therapy
GB201522636D0 (en) Delivery system
GB201522291D0 (en) Delivery vehicle
HK1206556A2 (en) Information delivery method
GB201405197D0 (en) Delivery suite- whelping system
AU2015900021A0 (en) Continuous delivery technique
HU4501U (en) Delivery slip