SG11201809004PA - (+)-azasetron for use in the treatment of ear disorders - Google Patents

(+)-azasetron for use in the treatment of ear disorders

Info

Publication number
SG11201809004PA
SG11201809004PA SG11201809004PA SG11201809004PA SG11201809004PA SG 11201809004P A SG11201809004P A SG 11201809004PA SG 11201809004P A SG11201809004P A SG 11201809004PA SG 11201809004P A SG11201809004P A SG 11201809004PA SG 11201809004P A SG11201809004P A SG 11201809004PA
Authority
SG
Singapore
Prior art keywords
international
pct
azasetron
ear disorders
rue
Prior art date
Application number
SG11201809004PA
Inventor
Jonas Dyhrfjeld-Johnsen
Original Assignee
Sensorion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sensorion filed Critical Sensorion
Publication of SG11201809004PA publication Critical patent/SG11201809004PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/5381,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 19 October 2017 (19.10.2017) WIPO I PCT (10) International Publication Number WO 2017/178645 Al 1111111111111101110111111111110101111101110101111101111111111111111111111110111111 (51) International Patent Classification: A61K 31/538 (2006.01) A61P 27/16 (2006.01) (21) International Application Number: PCT/EP2017/059058 (22) International Filing Date: 14 April 2017 (14.04.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/322,690 14 April 2016 (14.04.2016) US 16180192.3 19 July 2016 (19.07.2016) EP (71) Applicant: SENSORION [FR/FR]; 375 rue du Professeur Joseph Blayac, 34080 Montpellier (FR). (72) Inventor: DYHRFJELD-JOHNSEN, Jonas; 28 rue du Dardalhon, 34400 Lunel-Viel (FR). (74) Agent: ICOSA; 83 avenue Denfert-Rochereau, 75014 Par- is (FR). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — of inventorship (Rule 4.17(iv)) Published: — with international search report (Art. 21(3)) W O 20 1717 / 86 45 Al (54) Title: (+)-AZASETRON FOR USE IN THE TREATMENT OF EAR DISORDERS (57) : The present invention relates to (+)-azasetron, or a pharmaceutically acceptable salt and/or solvate thereof, for treat - ing ear disorders.
SG11201809004PA 2016-04-14 2017-04-14 (+)-azasetron for use in the treatment of ear disorders SG11201809004PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662322690P 2016-04-14 2016-04-14
EP16180192 2016-07-19
PCT/EP2017/059058 WO2017178645A1 (en) 2016-04-14 2017-04-14 (+)-azasetron for use in the treatment of ear disorders

Publications (1)

Publication Number Publication Date
SG11201809004PA true SG11201809004PA (en) 2018-11-29

Family

ID=60042388

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201809004PA SG11201809004PA (en) 2016-04-14 2017-04-14 (+)-azasetron for use in the treatment of ear disorders

Country Status (9)

Country Link
EP (1) EP3442537B1 (en)
KR (1) KR102429935B1 (en)
AU (1) AU2017248618B2 (en)
BR (1) BR112018071123A2 (en)
CA (1) CA3020847A1 (en)
EA (1) EA038516B1 (en)
MA (1) MA44660B1 (en)
SG (1) SG11201809004PA (en)
WO (1) WO2017178645A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220265668A1 (en) 2019-07-25 2022-08-25 Sensorion Treatment and/or prevention of lesions in the central auditory nervous system
TW202400180A (en) * 2022-03-16 2024-01-01 法商聖索瑞恩公司 Azasetron for the treatment of sudden sensorineural hearing loss

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1304082C (en) 1987-10-22 1992-06-23 Tetsuya Tahara Benzoxazine compounds and pharmaceutical use thereof
GB0104554D0 (en) * 2001-02-23 2001-04-11 Glaxo Group Ltd New uses
AU2003216379A1 (en) * 2002-02-22 2003-09-09 Control Delivery Systems, Inc. Method for treating otic disorders
PT2432467T (en) * 2009-05-20 2018-04-04 Inst Nat Sante Rech Med Serotonin 5-ht3 receptor antagonists for use in the treatment of lesional vestibular disorders
ES2432618T3 (en) * 2009-05-20 2013-12-04 Inserm (Institut National De La Santé Et De La Recherche Medicale) Serotonin 5-HT3 receptor antagonists for use in the treatment or prevention of a pathology of the inner ear with vestibular deficit
CN101786963B (en) 2010-03-03 2013-05-08 山东众诚药业股份有限公司 Synthesis method of Azasetron intermediate
CN104557906A (en) 2015-01-21 2015-04-29 扬子江药业集团四川海蓉药业有限公司 Method for preparing azasetron hydrochloride
PL3297628T3 (en) * 2015-05-18 2021-12-06 Sensorion Azasetron for use in the treatment of hearing loss

Also Published As

Publication number Publication date
AU2017248618A1 (en) 2018-11-08
KR20180129923A (en) 2018-12-05
MA44660B1 (en) 2024-03-29
BR112018071123A2 (en) 2019-02-05
WO2017178645A1 (en) 2017-10-19
KR102429935B1 (en) 2022-08-08
AU2017248618B2 (en) 2023-02-09
EP3442537A1 (en) 2019-02-20
EP3442537B1 (en) 2024-01-10
EA038516B1 (en) 2021-09-09
CA3020847A1 (en) 2017-10-19
EA201800565A1 (en) 2019-03-29
MA44660A (en) 2019-02-20

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