SG11201800510WA - New effective aminoglycoside antibiotic for multidrug-resistant bacteria - Google Patents
New effective aminoglycoside antibiotic for multidrug-resistant bacteriaInfo
- Publication number
- SG11201800510WA SG11201800510WA SG11201800510WA SG11201800510WA SG11201800510WA SG 11201800510W A SG11201800510W A SG 11201800510WA SG 11201800510W A SG11201800510W A SG 11201800510WA SG 11201800510W A SG11201800510W A SG 11201800510WA SG 11201800510W A SG11201800510W A SG 11201800510WA
- Authority
- SG
- Singapore
- Prior art keywords
- multidrug
- resistant bacteria
- new effective
- aminoglycoside antibiotic
- effective aminoglycoside
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015151250 | 2015-07-30 | ||
| PCT/JP2016/072400 WO2017018528A1 (en) | 2015-07-30 | 2016-07-29 | Novel aminoglycoside antibiotic effective against multidrug-resistant bacteria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201800510WA true SG11201800510WA (en) | 2018-02-27 |
Family
ID=57884581
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201913231RA SG10201913231RA (en) | 2015-07-30 | 2016-07-29 | New effective aminoglycoside antibiotic for multidrug-resistant bacteria |
| SG11201800510WA SG11201800510WA (en) | 2015-07-30 | 2016-07-29 | New effective aminoglycoside antibiotic for multidrug-resistant bacteria |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201913231RA SG10201913231RA (en) | 2015-07-30 | 2016-07-29 | New effective aminoglycoside antibiotic for multidrug-resistant bacteria |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US10617704B2 (en) |
| EP (2) | EP3330275A4 (en) |
| JP (1) | JP6938376B2 (en) |
| KR (1) | KR102590696B1 (en) |
| CN (1) | CN108026133B (en) |
| AR (1) | AR105547A1 (en) |
| AU (1) | AU2016300993B2 (en) |
| CA (1) | CA2993425A1 (en) |
| CL (1) | CL2018000228A1 (en) |
| CO (1) | CO2018001237A2 (en) |
| HK (1) | HK1254239A1 (en) |
| IL (1) | IL257151B (en) |
| MX (1) | MX2018001022A (en) |
| MY (1) | MY186959A (en) |
| PH (1) | PH12018500202A1 (en) |
| RU (1) | RU2751634C2 (en) |
| SA (1) | SA518390825B1 (en) |
| SG (2) | SG10201913231RA (en) |
| TW (1) | TWI699372B (en) |
| UA (1) | UA123629C2 (en) |
| WO (1) | WO2017018528A1 (en) |
| ZA (1) | ZA201801312B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR105547A1 (en) * | 2015-07-30 | 2017-10-11 | Microbial Chem Res Found | AMINOGLUCOSIDE ANTIBIOTICS FOR MULTIPLE DRUG-RESISTANT BACTERIA |
| JP2020055749A (en) * | 2017-01-27 | 2020-04-09 | 公益財団法人微生物化学研究会 | Novel aminoglycoside antibiotic effective for multiple drug-resistant bacteria |
| JP7313631B2 (en) * | 2017-05-01 | 2023-07-25 | ウェイン ステート ユニバーシティー | Apramycin derivative |
| JP2021138615A (en) * | 2018-05-31 | 2021-09-16 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | Method for producing aminoglycoside antibiotic substance effective for multidrug-resistant bacteria |
| CN116462721B (en) * | 2023-04-18 | 2024-02-02 | 江南大学 | Antibacterial aminoglycoside derivative |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5782398A (en) | 1980-09-22 | 1982-05-22 | Lilly Co Eli | 2-deoxystreptamine aminoglycoside derivative |
| JPS5782399A (en) * | 1980-09-22 | 1982-05-22 | Lilly Co Eli | 2-deoxystreptamine aminoglycoside derivative and manufacture |
| US4424344A (en) | 1980-09-22 | 1984-01-03 | Eli Lilly And Company | 2-N-Acylated and 2-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides and process |
| US4468513A (en) | 1980-09-22 | 1984-08-28 | Eli Lilly And Company | 2'-N-Acylated and 2'-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides |
| US4424345A (en) | 1980-09-22 | 1984-01-03 | Eli Lilly And Company | 1-N-Acylated and 1-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides and process |
| JPS5772998A (en) | 1980-10-24 | 1982-05-07 | Shionogi & Co Ltd | Novel appamycin derivative |
| JPS5772999A (en) * | 1980-10-24 | 1982-05-07 | Shionogi & Co Ltd | Novel 5-deoxyapramycin |
| US4385585A (en) * | 1981-10-27 | 1983-05-31 | Copco, Inc. | Teakettle having whistle cap |
| US4360665A (en) * | 1981-12-24 | 1982-11-23 | Eli Lilly And Company | 4"-N-(Substituted)-apramycin antibiotic derivatives and intermediates therefor |
| US4379917A (en) * | 1981-12-24 | 1983-04-12 | Eli Lilly And Company | 6"-(Substituted)-apramycin antibiotic derivatives and intermediates and starting materials therefor |
| US4458065A (en) * | 1983-02-17 | 1984-07-03 | Eli Lilly And Company | 7-N-(Substituted-apramycin antibiotic derivatives and intermediates therefor |
| JP2009533345A (en) | 2006-04-07 | 2009-09-17 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | Chemical synthesis of lipochitooligosaccharides |
| AU2007255856B2 (en) * | 2006-06-02 | 2012-08-16 | Meiji Seika Pharma Co., Ltd. | Novel aminoglycoside antibiotic |
| AU2008326297B2 (en) | 2007-11-21 | 2012-11-08 | Cipla USA, Inc. | Antibacterial aminoglycoside analogs |
| TWI472521B (en) | 2008-07-17 | 2015-02-11 | Lexicon Pharmaceuticals Inc | Solid forms of (2s,3r,4r,5s,6r)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2h-pyran-3,4,5-triol and methods of their use |
| US9271993B2 (en) | 2010-09-13 | 2016-03-01 | University Of Zurich | Treatment of bacterial infectious diseases |
| WO2013191550A1 (en) * | 2012-06-20 | 2013-12-27 | Rijksuniversiteit Groningen | Regioselective diazotation of aminoglycosides |
| RU2491921C1 (en) * | 2012-07-11 | 2013-09-10 | Общество с ограниченной ответственностью "Опытно-технологическая фирма "Этрис" | Method of treating mastitis in non-lactating cows |
| AR105547A1 (en) * | 2015-07-30 | 2017-10-11 | Microbial Chem Res Found | AMINOGLUCOSIDE ANTIBIOTICS FOR MULTIPLE DRUG-RESISTANT BACTERIA |
-
2016
- 2016-07-29 AR ARP160102333A patent/AR105547A1/en unknown
- 2016-07-29 SG SG10201913231RA patent/SG10201913231RA/en unknown
- 2016-07-29 WO PCT/JP2016/072400 patent/WO2017018528A1/en active Application Filing
- 2016-07-29 CA CA2993425A patent/CA2993425A1/en active Pending
- 2016-07-29 KR KR1020187005745A patent/KR102590696B1/en active IP Right Grant
- 2016-07-29 JP JP2017530947A patent/JP6938376B2/en active Active
- 2016-07-29 RU RU2018107150A patent/RU2751634C2/en active
- 2016-07-29 TW TW105124162A patent/TWI699372B/en active
- 2016-07-29 MX MX2018001022A patent/MX2018001022A/en unknown
- 2016-07-29 AU AU2016300993A patent/AU2016300993B2/en active Active
- 2016-07-29 CN CN201680044421.1A patent/CN108026133B/en active Active
- 2016-07-29 US US15/747,581 patent/US10617704B2/en active Active
- 2016-07-29 UA UAA201802040A patent/UA123629C2/en unknown
- 2016-07-29 EP EP16830631.4A patent/EP3330275A4/en not_active Withdrawn
- 2016-07-29 SG SG11201800510WA patent/SG11201800510WA/en unknown
- 2016-07-29 EP EP19154615.9A patent/EP3498723A1/en active Pending
- 2016-07-29 MY MYPI2018700342A patent/MY186959A/en unknown
-
2018
- 2018-01-25 PH PH12018500202A patent/PH12018500202A1/en unknown
- 2018-01-25 IL IL257151A patent/IL257151B/en active IP Right Grant
- 2018-01-26 CL CL2018000228A patent/CL2018000228A1/en unknown
- 2018-01-28 SA SA518390825A patent/SA518390825B1/en unknown
- 2018-02-06 CO CONC2018/0001237A patent/CO2018001237A2/en unknown
- 2018-02-26 ZA ZA2018/01312A patent/ZA201801312B/en unknown
- 2018-10-18 HK HK18113382.9A patent/HK1254239A1/en unknown
-
2020
- 2020-01-22 US US16/749,191 patent/US11135234B2/en active Active
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