SG11201710345VA - Imidazodiazepine compound - Google Patents

Imidazodiazepine compound

Info

Publication number
SG11201710345VA
SG11201710345VA SG11201710345VA SG11201710345VA SG11201710345VA SG 11201710345V A SG11201710345V A SG 11201710345VA SG 11201710345V A SG11201710345V A SG 11201710345VA SG 11201710345V A SG11201710345V A SG 11201710345VA SG 11201710345V A SG11201710345V A SG 11201710345VA
Authority
SG
Singapore
Prior art keywords
imidazodiazepine
compound
imidazodiazepine compound
Prior art date
Application number
SG11201710345VA
Inventor
Shimpei Kawakami
Tomoyoshi Imaizumi
Naoyuki Masuda
Shigeki Kunikawa
Masataka Morita
Junko Yarimizu
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of SG11201710345VA publication Critical patent/SG11201710345VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11201710345VA 2015-06-19 2016-06-17 Imidazodiazepine compound SG11201710345VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015123478 2015-06-19
PCT/JP2016/068080 WO2016204268A1 (en) 2015-06-19 2016-06-17 Imidazodiazepine compound

Publications (1)

Publication Number Publication Date
SG11201710345VA true SG11201710345VA (en) 2018-01-30

Family

ID=57546103

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201710345VA SG11201710345VA (en) 2015-06-19 2016-06-17 Imidazodiazepine compound

Country Status (29)

Country Link
US (1) US10426784B2 (en)
EP (1) EP3312181B1 (en)
JP (1) JP6658753B2 (en)
KR (1) KR102591169B1 (en)
CN (2) CN111205292B (en)
AR (1) AR105025A1 (en)
AU (1) AU2016279518B2 (en)
CA (1) CA2989982C (en)
CO (1) CO2018000431A2 (en)
CY (1) CY1122232T1 (en)
DK (1) DK3312181T3 (en)
ES (1) ES2751913T3 (en)
HR (1) HRP20191961T1 (en)
HU (1) HUE047430T2 (en)
IL (1) IL256252B (en)
LT (1) LT3312181T (en)
MX (1) MX2017016690A (en)
MY (1) MY197499A (en)
PH (1) PH12017502253A1 (en)
PL (1) PL3312181T3 (en)
PT (1) PT3312181T (en)
RS (1) RS59497B1 (en)
RU (1) RU2712968C2 (en)
SG (1) SG11201710345VA (en)
SI (1) SI3312181T1 (en)
TW (1) TWI697496B (en)
UA (1) UA120006C2 (en)
WO (1) WO2016204268A1 (en)
ZA (1) ZA201708566B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI725408B (en) 2018-04-20 2021-04-21 美商美國禮來大藥廠 Dopamine d1 receptor positive allosteric modulators

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0210391A (en) * 2001-06-12 2004-06-15 Elan Pharm Inc Compound, methods of treating a patient who has or prevent a patient from contracting a disease or condition and preparing a compound, and, using a compound
EP1496838B1 (en) 2002-03-12 2010-11-03 Merck Sharp & Dohme Corp. Substituted amides
WO2004000837A1 (en) * 2002-06-25 2003-12-31 Sumitomo Pharmaceuticals Co., Ltd. Novel benzoxazolinone derivative
WO2005080335A1 (en) * 2004-02-13 2005-09-01 President And Fellows Of Harvard College 3-3-di-substituted-oxindoles as inhibitors of translation initiation
AU2005214258A1 (en) 2004-02-23 2005-09-01 Dainippon Sumitomo Pharma Co., Ltd. Novel heterocyclic compound
CA2567909A1 (en) * 2004-05-27 2005-12-15 Ucb, S.A. Benzoxazolone derivatives, processes for preparing them and their uses
CL2007002097A1 (en) 2006-07-20 2008-01-18 Smithkline Beecham Corp Compounds derived from pyrrolidine or morpholine antagonists of urotensin ii; pharmaceutical composition comprising said compounds; and its use to treat congestive heart failure, ischemic heart failure, angina, myocardial ischemia, overactive bladder, asthma and / or copd, among others.
PE20081229A1 (en) * 2006-12-01 2008-08-28 Merck & Co Inc DIAZEPAM OREXIN RECEPTOR ANTAGONISTS REPLACED
PE20130346A1 (en) * 2010-06-24 2013-03-30 Takeda Pharmaceutical FUSED HETEROCYCLIC COMPOUNDS
AR095883A1 (en) 2013-04-18 2015-11-18 Astellas Pharma Inc HETEROCYCLIC ACETAMIDE COMPOUNDS

Also Published As

Publication number Publication date
PH12017502253A1 (en) 2018-05-28
HUE047430T2 (en) 2020-04-28
MX2017016690A (en) 2018-03-15
IL256252A (en) 2018-02-28
CN107635996B (en) 2020-05-26
CY1122232T1 (en) 2020-11-25
AU2016279518A1 (en) 2018-01-04
DK3312181T3 (en) 2019-10-28
PL3312181T3 (en) 2020-01-31
EP3312181B1 (en) 2019-08-07
ZA201708566B (en) 2019-06-26
EP3312181A1 (en) 2018-04-25
LT3312181T (en) 2019-10-10
IL256252B (en) 2021-01-31
CO2018000431A2 (en) 2018-04-10
MY197499A (en) 2023-06-19
PT3312181T (en) 2019-10-29
JPWO2016204268A1 (en) 2018-04-05
RS59497B1 (en) 2019-12-31
RU2018101861A3 (en) 2019-08-06
ES2751913T3 (en) 2020-04-02
US10426784B2 (en) 2019-10-01
SI3312181T1 (en) 2020-02-28
RU2020103225A (en) 2020-02-04
CN111205292B (en) 2022-06-21
JP6658753B2 (en) 2020-03-04
HRP20191961T1 (en) 2020-02-07
CA2989982C (en) 2023-08-15
RU2018101861A (en) 2019-07-19
KR102591169B1 (en) 2023-10-18
TW201713662A (en) 2017-04-16
CN107635996A (en) 2018-01-26
AR105025A1 (en) 2017-08-30
RU2020103225A3 (en) 2022-02-18
TWI697496B (en) 2020-07-01
EP3312181A4 (en) 2018-11-21
WO2016204268A1 (en) 2016-12-22
AU2016279518B2 (en) 2020-01-16
RU2712968C2 (en) 2020-02-03
CA2989982A1 (en) 2016-12-22
CN111205292A (en) 2020-05-29
KR20180014732A (en) 2018-02-09
US20180185383A1 (en) 2018-07-05
UA120006C2 (en) 2019-09-10

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