SG11201709782SA - Xanthine derivative - Google Patents
Xanthine derivativeInfo
- Publication number
- SG11201709782SA SG11201709782SA SG11201709782SA SG11201709782SA SG11201709782SA SG 11201709782S A SG11201709782S A SG 11201709782SA SG 11201709782S A SG11201709782S A SG 11201709782SA SG 11201709782S A SG11201709782S A SG 11201709782SA SG 11201709782S A SG11201709782S A SG 11201709782SA
- Authority
- SG
- Singapore
- Prior art keywords
- xanthine derivative
- xanthine
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510290336 | 2015-05-29 | ||
| PCT/CN2016/083406 WO2016192559A1 (en) | 2015-05-29 | 2016-05-26 | Xanthine derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201709782SA true SG11201709782SA (en) | 2017-12-28 |
Family
ID=57440191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201709782SA SG11201709782SA (en) | 2015-05-29 | 2016-05-26 | Xanthine derivative |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US10358449B2 (en) |
| EP (1) | EP3305787B1 (en) |
| JP (1) | JP6742345B2 (en) |
| KR (1) | KR20180011270A (en) |
| CN (2) | CN106188058B (en) |
| AU (1) | AU2016270100B2 (en) |
| CA (1) | CA2987697A1 (en) |
| ES (1) | ES2908658T3 (en) |
| HK (1) | HK1245796A1 (en) |
| IL (1) | IL255829B (en) |
| MY (1) | MY186396A (en) |
| RU (1) | RU2709348C2 (en) |
| SG (1) | SG11201709782SA (en) |
| TW (1) | TWI682931B (en) |
| WO (1) | WO2016192559A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105983016B (en) | 2015-03-23 | 2023-08-11 | 天士力医药集团股份有限公司 | A pharmaceutical composition containing silybin |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW492957B (en) | 1996-11-07 | 2002-07-01 | Novartis Ag | N-substituted 2-cyanopyrrolidnes |
| US6110949A (en) | 1999-06-24 | 2000-08-29 | Novartis Ag | N-(substituted glycyl)-4-cyanothiazolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV |
| EP1496877B1 (en) * | 2002-01-11 | 2008-10-01 | Novo Nordisk A/S | Method and composition for treatment of diabetes, hypertension, chronic heart failure and fluid retentive states |
| US7482337B2 (en) * | 2002-11-08 | 2009-01-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions |
| US7501426B2 (en) * | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
| EP2119717B1 (en) * | 2004-02-18 | 2018-01-17 | Boehringer Ingelheim International GmbH | 8-[3-amino-piperidin-1-yl]-xanthins, their production and utilisation as DPP IV inhibitors |
| DE102004008112A1 (en) * | 2004-02-18 | 2005-09-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New 8-aminopiperidinyl-xanthine derivatives, useful for treating e.g. diabetes, arthritis and osteoporosis, are inhibitors of dipeptidylpeptidase-IV |
| DE102004054054A1 (en) * | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Process for preparing chiral 8- (3-amino-piperidin-1-yl) -xanthines |
| DE102005035891A1 (en) * | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8- (3-amino-piperidin-1-yl) -xanthines, their preparation and their use as pharmaceuticals |
| PE20100156A1 (en) * | 2008-06-03 | 2010-02-23 | Boehringer Ingelheim Int | NAFLD TREATMENT |
| UY32030A (en) * | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "TREATMENT FOR DIABETES IN INAPPROPRIATE PATIENTS FOR THERAPY WITH METFORMIN" |
| AU2009281122C1 (en) * | 2008-08-15 | 2016-04-21 | Boehringer Ingelheim International Gmbh | Purin derivatives for use in the treatment of fab-related diseases |
| UY32177A (en) * | 2008-10-16 | 2010-05-31 | Boehringer Ingelheim Int | TREATMENT OF DIABETES IN PATIENTS WITH INSUFFICIENT GLUCEMIC CONTROL TO WEIGHT THERAPY WITH DRUG, ORAL OR NOT, ANTIDIABÉTICO |
| CN103172633B (en) * | 2011-12-22 | 2016-08-03 | 成都地奥制药集团有限公司 | A kind of compound and its production and use |
-
2016
- 2016-05-25 CN CN201610356576.0A patent/CN106188058B/en active Active
- 2016-05-25 TW TW105116298A patent/TWI682931B/en not_active IP Right Cessation
- 2016-05-26 EP EP16802482.6A patent/EP3305787B1/en active Active
- 2016-05-26 CN CN201680031442.XA patent/CN107709324B/en active Active
- 2016-05-26 MY MYPI2017704554A patent/MY186396A/en unknown
- 2016-05-26 CA CA2987697A patent/CA2987697A1/en active Pending
- 2016-05-26 JP JP2017561869A patent/JP6742345B2/en not_active Expired - Fee Related
- 2016-05-26 SG SG11201709782SA patent/SG11201709782SA/en unknown
- 2016-05-26 KR KR1020177037626A patent/KR20180011270A/en not_active Application Discontinuation
- 2016-05-26 WO PCT/CN2016/083406 patent/WO2016192559A1/en active Application Filing
- 2016-05-26 AU AU2016270100A patent/AU2016270100B2/en not_active Ceased
- 2016-05-26 RU RU2017145919A patent/RU2709348C2/en active
- 2016-05-26 US US15/577,946 patent/US10358449B2/en active Active
- 2016-05-26 ES ES16802482T patent/ES2908658T3/en active Active
-
2017
- 2017-11-21 IL IL255829A patent/IL255829B/en active IP Right Grant
-
2018
- 2018-04-27 HK HK18105484.2A patent/HK1245796A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2017145919A (en) | 2019-07-02 |
| TW201643166A (en) | 2016-12-16 |
| RU2017145919A3 (en) | 2019-08-09 |
| HK1245796A1 (en) | 2018-08-31 |
| JP2018520120A (en) | 2018-07-26 |
| CN106188058B (en) | 2020-11-06 |
| IL255829B (en) | 2021-02-28 |
| MY186396A (en) | 2021-07-22 |
| CN107709324A (en) | 2018-02-16 |
| JP6742345B2 (en) | 2020-08-19 |
| EP3305787A4 (en) | 2018-11-21 |
| ES2908658T3 (en) | 2022-05-03 |
| EP3305787B1 (en) | 2022-02-16 |
| WO2016192559A1 (en) | 2016-12-08 |
| AU2016270100A1 (en) | 2017-12-14 |
| RU2709348C2 (en) | 2019-12-18 |
| US10358449B2 (en) | 2019-07-23 |
| US20180162860A1 (en) | 2018-06-14 |
| AU2016270100B2 (en) | 2020-02-13 |
| IL255829A (en) | 2018-01-31 |
| CA2987697A1 (en) | 2016-12-08 |
| KR20180011270A (en) | 2018-01-31 |
| TWI682931B (en) | 2020-01-21 |
| CN106188058A (en) | 2016-12-07 |
| EP3305787A1 (en) | 2018-04-11 |
| CN107709324B (en) | 2021-06-08 |
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