SG11201708395VA - Method for producing stem cell clones suitable for induction of differentiation into somatic cells - Google Patents
Method for producing stem cell clones suitable for induction of differentiation into somatic cellsInfo
- Publication number
- SG11201708395VA SG11201708395VA SG11201708395VA SG11201708395VA SG11201708395VA SG 11201708395V A SG11201708395V A SG 11201708395VA SG 11201708395V A SG11201708395V A SG 11201708395VA SG 11201708395V A SG11201708395V A SG 11201708395VA SG 11201708395V A SG11201708395V A SG 11201708395VA
- Authority
- SG
- Singapore
- Prior art keywords
- differentiation
- induction
- stem cell
- somatic cells
- cell clones
- Prior art date
Links
- 230000004069 differentiation Effects 0.000 title 1
- 230000006698 induction Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 210000001082 somatic cell Anatomy 0.000 title 1
- 210000000130 stem cell Anatomy 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0644—Platelets; Megakaryocytes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/145—Thrombopoietin [TPO]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/602—Sox-2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/604—Klf-4
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Developmental Biology & Embryology (AREA)
- Transplantation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015082768 | 2015-04-14 | ||
| PCT/JP2016/062040 WO2016167329A1 (en) | 2015-04-14 | 2016-04-14 | Method for producing stem cell clones suitable for induction of differentiation into somatic cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201708395VA true SG11201708395VA (en) | 2017-11-29 |
Family
ID=57126279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201708395VA SG11201708395VA (en) | 2015-04-14 | 2016-04-14 | Method for producing stem cell clones suitable for induction of differentiation into somatic cells |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20180051260A1 (en) |
| EP (1) | EP3296390B1 (en) |
| JP (1) | JP6873898B2 (en) |
| KR (1) | KR102563564B1 (en) |
| CN (1) | CN107709543B (en) |
| AU (1) | AU2016248858A1 (en) |
| BR (1) | BR112017022219A2 (en) |
| CA (1) | CA2982568A1 (en) |
| IL (1) | IL255031B (en) |
| RU (1) | RU2730034C2 (en) |
| SG (1) | SG11201708395VA (en) |
| WO (1) | WO2016167329A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108866005A (en) * | 2018-07-20 | 2018-11-23 | 东南大学 | A kind of immortal human derived neural stem cell line and preparation method thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2208786B1 (en) * | 2005-12-13 | 2018-08-01 | Kyoto University | Nuclear reprogramming factor |
| WO2010033920A2 (en) * | 2008-09-19 | 2010-03-25 | Whitehead Institute For Biomedical Research | Compositions and methods for enhancing cell reprogramming |
| DK3450545T3 (en) * | 2008-10-24 | 2023-10-02 | Wisconsin Alumni Res Found | Pluripotent stem cells obtained by non-viral reprogramming |
| JP5791191B2 (en) * | 2009-09-15 | 2015-10-07 | 国立大学法人 東京大学 | New method for producing differentiated cells |
| JP5745423B2 (en) * | 2009-10-28 | 2015-07-08 | 公益財団法人ヒューマンサイエンス振興財団 | Differentiation induction method from stem cells to hepatocytes |
| JPWO2011096482A1 (en) * | 2010-02-03 | 2013-06-13 | 国立大学法人 東京大学 | Immune function reconstruction using pluripotent stem cells |
| US20120009158A1 (en) * | 2010-06-18 | 2012-01-12 | The General Hospital Corporation | VENTRICULAR INDUCED PLURIPOTENT STEM (ViPS) CELLS FOR GENERATION OF AUTOLOGOUS VENTRICULAR CARDIOMYOCYTES AND USES THEREOF |
| JP5824760B2 (en) * | 2011-05-13 | 2015-12-02 | 国立大学法人 東京大学 | Multinucleated megakaryocyte cells and method for producing platelets |
| CN103703130A (en) * | 2011-07-25 | 2014-04-02 | 国立大学法人京都大学 | Method for screening induced pluripotent stem cells |
| JP2013240308A (en) * | 2012-05-23 | 2013-12-05 | Kagoshima Univ | METHOD FOR EXPRESSING GENE IN HUMAN ES/iPS CELL |
| JP6495658B2 (en) * | 2013-02-08 | 2019-04-03 | 国立大学法人京都大学 | Method for producing megakaryocytes and platelets |
| SG11201507829SA (en) | 2013-03-21 | 2015-12-30 | Univ Kyoto | Pluripotent stem cell for neuronal differentiation induction |
-
2016
- 2016-04-14 SG SG11201708395VA patent/SG11201708395VA/en unknown
- 2016-04-14 JP JP2017512584A patent/JP6873898B2/en active Active
- 2016-04-14 BR BR112017022219A patent/BR112017022219A2/en not_active Application Discontinuation
- 2016-04-14 EP EP16780120.8A patent/EP3296390B1/en active Active
- 2016-04-14 AU AU2016248858A patent/AU2016248858A1/en not_active Abandoned
- 2016-04-14 CN CN201680034787.0A patent/CN107709543B/en active Active
- 2016-04-14 US US15/565,922 patent/US20180051260A1/en not_active Abandoned
- 2016-04-14 KR KR1020177032755A patent/KR102563564B1/en active IP Right Grant
- 2016-04-14 WO PCT/JP2016/062040 patent/WO2016167329A1/en active Application Filing
- 2016-04-14 RU RU2017139241A patent/RU2730034C2/en active
- 2016-04-14 CA CA2982568A patent/CA2982568A1/en not_active Abandoned
-
2017
- 2017-10-15 IL IL255031A patent/IL255031B/en unknown
-
2020
- 2020-04-03 US US16/839,906 patent/US20210062158A1/en not_active Abandoned
-
2023
- 2023-09-27 US US18/476,065 patent/US20240026304A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3296390A4 (en) | 2019-01-09 |
| US20240026304A1 (en) | 2024-01-25 |
| US20210062158A1 (en) | 2021-03-04 |
| JP6873898B2 (en) | 2021-05-19 |
| CN107709543B (en) | 2021-11-09 |
| RU2730034C2 (en) | 2020-08-14 |
| AU2016248858A1 (en) | 2017-11-09 |
| IL255031B (en) | 2022-04-01 |
| RU2017139241A3 (en) | 2019-09-16 |
| CA2982568A1 (en) | 2016-10-20 |
| US20180051260A1 (en) | 2018-02-22 |
| EP3296390A1 (en) | 2018-03-21 |
| RU2017139241A (en) | 2019-05-14 |
| IL255031A0 (en) | 2017-12-31 |
| KR20180019519A (en) | 2018-02-26 |
| KR102563564B1 (en) | 2023-08-07 |
| EP3296390B1 (en) | 2023-01-04 |
| WO2016167329A1 (en) | 2016-10-20 |
| JPWO2016167329A1 (en) | 2018-02-15 |
| CN107709543A (en) | 2018-02-16 |
| BR112017022219A2 (en) | 2018-07-31 |
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