SG11201708194WA - Fusion proteins - Google Patents

Fusion proteins

Info

Publication number
SG11201708194WA
SG11201708194WA SG11201708194WA SG11201708194WA SG11201708194WA SG 11201708194W A SG11201708194W A SG 11201708194WA SG 11201708194W A SG11201708194W A SG 11201708194WA SG 11201708194W A SG11201708194W A SG 11201708194WA SG 11201708194W A SG11201708194W A SG 11201708194WA
Authority
SG
Singapore
Prior art keywords
fusion proteins
fusion
proteins
Prior art date
Application number
SG11201708194WA
Inventor
David Bruce Baldwin
John Michael Beals
Jonathan Wesley Day
Craig Duane Dickinson
Andrew Ihor Korytko
Gregory Alan Lazar
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55953435&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201708194W(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SG11201708194WA publication Critical patent/SG11201708194WA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
SG11201708194WA 2015-05-07 2016-04-28 Fusion proteins SG11201708194WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562158079P 2015-05-07 2015-05-07
PCT/US2016/029807 WO2016178905A1 (en) 2015-05-07 2016-04-28 Fusion proteins

Publications (1)

Publication Number Publication Date
SG11201708194WA true SG11201708194WA (en) 2017-11-29

Family

ID=55953435

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201708194WA SG11201708194WA (en) 2015-05-07 2016-04-28 Fusion proteins

Country Status (42)

Country Link
US (4) US9855318B2 (en)
EP (1) EP3292141B1 (en)
JP (1) JP6591562B2 (en)
KR (1) KR102059736B1 (en)
CN (1) CN107531806B (en)
AR (1) AR105616A1 (en)
AU (1) AU2016257659B2 (en)
BR (1) BR112017020502A2 (en)
CA (1) CA2981102A1 (en)
CL (1) CL2017002761A1 (en)
CO (1) CO2017011301A2 (en)
CR (1) CR20170469A (en)
CY (1) CY1122929T1 (en)
DK (1) DK3292141T3 (en)
DO (1) DOP2017000258A (en)
EA (1) EA039770B1 (en)
EC (1) ECSP17073650A (en)
ES (1) ES2799099T3 (en)
HK (1) HK1244019A1 (en)
HR (1) HRP20200503T1 (en)
IL (1) IL254965B (en)
JO (1) JO3658B1 (en)
LT (1) LT3292141T (en)
MA (1) MA42037B1 (en)
MD (1) MD3292141T2 (en)
ME (1) ME03709B (en)
MX (1) MX2017014284A (en)
MY (1) MY183025A (en)
NZ (1) NZ736470A (en)
PE (1) PE20180507A1 (en)
PH (1) PH12017502025A1 (en)
PL (1) PL3292141T3 (en)
PT (1) PT3292141T (en)
RS (1) RS60044B1 (en)
SG (1) SG11201708194WA (en)
SI (1) SI3292141T1 (en)
SV (1) SV2017005548A (en)
TN (1) TN2018000059A1 (en)
TW (1) TWI656132B (en)
UA (1) UA122146C2 (en)
WO (1) WO2016178905A1 (en)
ZA (1) ZA201706334B (en)

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EP3939605A1 (en) * 2016-12-09 2022-01-19 Akston Biosciences Corporation Insulin-fc fusions and methods of use
TR201703622A1 (en) * 2017-03-09 2018-09-21 Univ Yeditepe A PRODUCT FOR OBESITY TREATMENT
CN110505885A (en) * 2017-04-05 2019-11-26 诺和诺德股份有限公司 Insulin-Fc the conjugate that oligomer extends
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WO2020005819A1 (en) 2018-06-25 2020-01-02 University Of Washington De novo design of potent and selective interleukin mimetics
FI4011908T3 (en) * 2018-06-29 2023-08-04 Akston Biosciences Corp Ultra-long acting insulin-fc fusion proteins and methods of use
US11267862B2 (en) 2018-06-29 2022-03-08 Akston Biosciences Corporation Ultra-long acting insulin-Fc fusion proteins and methods of use
EP3863680A1 (en) 2018-10-10 2021-08-18 Novo Nordisk A/S Oligomer extended insulin-fc conjugates and their medical use
MX2021005593A (en) 2018-11-20 2021-08-11 Univ Washington Split interleukin mimetics and their use.
WO2021011827A1 (en) * 2019-07-16 2021-01-21 Akston Biosciences Corporation Ultra-long acting insulin-fc fusion proteins and methods of use
JP2022542301A (en) 2019-07-31 2022-09-30 イーライ リリー アンド カンパニー RELAXIN ANALOGUES AND METHODS OF USE THEREOF
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US11186623B2 (en) 2019-12-24 2021-11-30 Akston Bioscience Corporation Ultra-long acting insulin-Fc fusion proteins and methods of use
US20230340071A1 (en) 2020-03-16 2023-10-26 Neoleukin Therapeutics, Inc. Interleukin-2 Receptor Beta (IL-2RB) Binding Polypeptides
KR20220164736A (en) 2020-04-07 2022-12-13 네오레우킨 테라퓨틱스, 인코포레이티드 De novo protein decoy of angiotensin converting enzyme 2 (ACE2)
US11213581B2 (en) 2020-04-10 2022-01-04 Akston Biosciences Corporation Antigen specific immunotherapy for COVID-19 fusion proteins and methods of use
US11192930B2 (en) 2020-04-10 2021-12-07 Askton Bioscences Corporation Ultra-long acting insulin-Fc fusion protein and methods of use
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EP4373861A2 (en) 2021-07-23 2024-05-29 Akston Biosciences Corporation Insulin-fc fusion proteins and methods of use to treat cancer
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Also Published As

Publication number Publication date
TN2018000059A1 (en) 2019-07-08
WO2016178905A1 (en) 2016-11-10
PH12017502025B1 (en) 2018-04-02
NZ736470A (en) 2019-04-26
JO3658B1 (en) 2020-08-27
TWI656132B (en) 2019-04-11
PE20180507A1 (en) 2018-03-09
MY183025A (en) 2021-02-07
BR112017020502A2 (en) 2018-07-03
HK1244019A1 (en) 2018-07-27
AR105616A1 (en) 2017-10-25
TW201712029A (en) 2017-04-01
JP2018515088A (en) 2018-06-14
US10709766B2 (en) 2020-07-14
US9855318B2 (en) 2018-01-02
US20200390865A1 (en) 2020-12-17
EP3292141A1 (en) 2018-03-14
ECSP17073650A (en) 2018-02-28
US20160324932A1 (en) 2016-11-10
PH12017502025A1 (en) 2018-04-02
RS60044B1 (en) 2020-04-30
ES2799099T3 (en) 2020-12-14
EA201792199A1 (en) 2018-03-30
LT3292141T (en) 2020-03-25
AU2016257659A1 (en) 2017-10-12
DOP2017000258A (en) 2017-12-31
PT3292141T (en) 2020-04-22
SV2017005548A (en) 2018-04-24
PL3292141T3 (en) 2020-06-29
SI3292141T1 (en) 2020-04-30
ZA201706334B (en) 2020-01-29
CA2981102A1 (en) 2016-11-10
MD3292141T2 (en) 2020-07-31
ME03709B (en) 2021-01-20
KR20170134614A (en) 2017-12-06
MA42037B1 (en) 2020-03-31
EA039770B1 (en) 2022-03-11
IL254965A0 (en) 2017-12-31
US20180177851A1 (en) 2018-06-28
IL254965B (en) 2021-03-25
MX2017014284A (en) 2018-03-23
AU2016257659B2 (en) 2018-08-09
US20220211818A1 (en) 2022-07-07
CR20170469A (en) 2017-11-14
EP3292141B1 (en) 2020-02-12
US11253574B2 (en) 2022-02-22
UA122146C2 (en) 2020-09-25
CY1122929T1 (en) 2021-10-29
CN107531806B (en) 2022-06-07
CO2017011301A2 (en) 2018-03-20
HRP20200503T1 (en) 2020-06-26
KR102059736B1 (en) 2019-12-26
CL2017002761A1 (en) 2018-05-18
DK3292141T3 (en) 2020-04-20
CN107531806A (en) 2018-01-02
JP6591562B2 (en) 2019-10-16

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