SG11201706117UA - Cell culture method using bone marrow-like structure, and polyimide porous membrane for treating bone damage site - Google Patents

Cell culture method using bone marrow-like structure, and polyimide porous membrane for treating bone damage site

Info

Publication number
SG11201706117UA
SG11201706117UA SG11201706117UA SG11201706117UA SG11201706117UA SG 11201706117U A SG11201706117U A SG 11201706117UA SG 11201706117U A SG11201706117U A SG 11201706117UA SG 11201706117U A SG11201706117U A SG 11201706117UA SG 11201706117U A SG11201706117U A SG 11201706117UA
Authority
SG
Singapore
Prior art keywords
cell culture
porous membrane
culture method
polyimide porous
damage site
Prior art date
Application number
SG11201706117UA
Inventor
Keisuke Ohta
Shingo Hirashima
Masahiko Hagihara
Motohisa Shimizu
Original Assignee
Ube Industries
Univ Kurume
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ube Industries, Univ Kurume filed Critical Ube Industries
Publication of SG11201706117UA publication Critical patent/SG11201706117UA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/36—After-treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0669—Bone marrow stromal cells; Whole bone marrow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3847—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2379/00—Characterised by the use of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen with or without oxygen, or carbon only, not provided for in groups C08J2361/00 - C08J2377/00
    • C08J2379/04—Polycondensates having nitrogen-containing heterocyclic rings in the main chain; Polyhydrazides; Polyamide acids or similar polyimide precursors
    • C08J2379/08—Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/14—Erythropoietin [EPO]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
SG11201706117UA 2015-01-26 2016-01-26 Cell culture method using bone marrow-like structure, and polyimide porous membrane for treating bone damage site SG11201706117UA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015012696 2015-01-26
JP2015012743 2015-01-26
PCT/JP2016/052215 WO2016121771A1 (en) 2015-01-26 2016-01-26 Cell culture method using bone marrow-like structure, and polyimide porous membrane for treating bone damage site

Publications (1)

Publication Number Publication Date
SG11201706117UA true SG11201706117UA (en) 2017-08-30

Family

ID=56543382

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201706117UA SG11201706117UA (en) 2015-01-26 2016-01-26 Cell culture method using bone marrow-like structure, and polyimide porous membrane for treating bone damage site

Country Status (7)

Country Link
US (2) US10590388B2 (en)
EP (2) EP3252150B1 (en)
JP (1) JP6358605B2 (en)
CN (1) CN107208058B (en)
CA (2) CA2974074C (en)
SG (1) SG11201706117UA (en)
WO (1) WO2016121771A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107208058B (en) 2015-01-26 2021-06-25 宇部兴产株式会社 Cell culture method using bone marrow-like structure, and polyimide porous membrane for treatment of bone injury site
JPWO2018021333A1 (en) * 2016-07-25 2019-05-16 宇部興産株式会社 Implants and kits for the treatment of bone injury sites and methods of treating bone injury sites
CN115350334B (en) * 2022-08-23 2023-03-10 广东工业大学 Preparation method, product and application of polyimide-based composite aerogel material

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63196286A (en) 1987-02-12 1988-08-15 Sumitomo Electric Ind Ltd Base for cell culture
JPS63198975A (en) * 1987-02-13 1988-08-17 Sumitomo Electric Ind Ltd Base material for cultivating cell
JPS63198978A (en) 1987-02-13 1988-08-17 Sumitomo Electric Ind Ltd Base material for cultivating cell
US5275602A (en) 1989-12-04 1994-01-04 Gunze Limited Bone-joining articles
JP3029266B2 (en) 1989-12-04 2000-04-04 グンゼ株式会社 Osteosynthesis material
NZ513303A (en) 1999-02-04 2003-03-28 Technion Res & Dev Foundation Three dimensional plug flow bioreactor, and its use for the maintenance and expansion of hemopoietic stem cells and/or progenitor cells
JP3421741B2 (en) 2000-05-18 2003-06-30 筑波大学長 Artificial bone marrow, blood cell proliferation method
EP1370194B1 (en) 2001-03-23 2013-01-23 Histogenics Corporation Composition and methods fro the production of biological tissues and tissue constructs
WO2003018077A1 (en) 2001-08-22 2003-03-06 National Institute Of Advanced Industrial Science And Technology Method of bone regeneration
JP4393908B2 (en) 2004-03-31 2010-01-06 Ｈｏｙａ株式会社 Cell adhesion method
JP2006230683A (en) 2005-02-24 2006-09-07 Olympus Corp Bone compensation material, bone compensation body and cultivated bone
WO2007015546A1 (en) 2005-08-04 2007-02-08 Genomix Co., Ltd Mesenchymal stem cell inducer, tissue regeneration promoter and method of preparing mesenchymal stem cell
US9095562B2 (en) * 2007-07-05 2015-08-04 Regenerative Sciences, Inc. Methods and compositions for optimized expansion and implantation of mesenchymal stem cells
CN102131919B (en) 2008-03-31 2017-05-03 东方酵母工业株式会社 Method for proliferation of pluripotent stem cell
EP2291556A2 (en) * 2008-06-10 2011-03-09 Technion Research & Development Foundation Ltd. Nonwoven structure and method of fabricating the same
WO2010038873A1 (en) * 2008-10-02 2010-04-08 宇部興産株式会社 Porous polyimide membrane and process for production of same
KR101747462B1 (en) * 2009-10-09 2017-06-14 우베 고산 가부시키가이샤 Colored polyimide molded article, and process for production thereof
JP5577803B2 (en) * 2010-04-07 2014-08-27 宇部興産株式会社 Porous polyimide membrane and method for producing the same
JP5577804B2 (en) * 2010-04-07 2014-08-27 宇部興産株式会社 Porous polyimide membrane and method for producing the same
US9295531B2 (en) * 2011-06-13 2016-03-29 Dentsply International Inc. Collagen coated article
US9402710B2 (en) * 2012-07-16 2016-08-02 The Board Of Trustees For The Leland Stanford Junior University Macroporous 3-D scaffolds for tissue engineering
US20160002599A1 (en) 2013-02-08 2016-01-07 Kyoto University Production methods for megakaryocytes and platelets
EP3026108B1 (en) 2013-07-26 2021-11-10 UBE Industries, Ltd. Cell culturing method, cell culturing apparatus and kit
EP3135752A4 (en) * 2014-04-22 2018-03-14 Nippon Shokubai Co., Ltd. Cell culture substrate containing fluorine-containing polymer on surface
JP6494756B2 (en) 2014-10-29 2019-04-03 アール バイオ カンパニー リミテッドＲ Ｂｉｏ Ｃｏ．， Ｌｔｄ． Medium composition for stem cell culture
CN107208058B (en) 2015-01-26 2021-06-25 宇部兴产株式会社 Cell culture method using bone marrow-like structure, and polyimide porous membrane for treatment of bone injury site
CA2974276C (en) * 2015-01-26 2019-07-30 Ube Industries, Ltd. Long-term cell-cultivation using polyimide porous membrane and cell-cryopreservation method using polyimide porous membrane

Also Published As

Publication number Publication date
EP3252150A4 (en) 2018-08-08
EP3406272B1 (en) 2020-12-30
WO2016121771A1 (en) 2016-08-04
US10590388B2 (en) 2020-03-17
CA2974074A1 (en) 2016-08-04
US10508264B2 (en) 2019-12-17
JPWO2016121771A1 (en) 2017-12-07
CA3024665C (en) 2021-04-20
CA3024665A1 (en) 2016-08-04
EP3252150B1 (en) 2021-10-27
EP3252150A1 (en) 2017-12-06
US20180237750A1 (en) 2018-08-23
US20180148693A1 (en) 2018-05-31
EP3406272A1 (en) 2018-11-28
CA2974074C (en) 2019-08-27
JP6358605B2 (en) 2018-07-18
CN107208058B (en) 2021-06-25
CN107208058A (en) 2017-09-26

Similar Documents

Publication Publication Date Title
HK1253095A1 (en) Cell culture device, system and methods of use thereof
SG11201705866XA (en) Method, device and kit for mass cultivation of cells using polyimide porous membrane
HK1251248A1 (en) Automated cell cultivation device, and method for operating cultivation device
EP3440186A4 (en) System, device and method for electroporation of cells
DK3279310T3 (en) CELL CULTIVATION APPARATUS AND CELL CULTURE METHOD
EP3390694A4 (en) Method and system for efficiently operating electrochemical cells
IL268433A (en) Cell culture system and method
EP3312268A4 (en) Cell culture method, jig for cell culture, and cell culture device
SG11201606934SA (en) Improved reprogramming methods and cell culture platforms
EP3162387A4 (en) Nano-fiber mat, method for manufacturing same, and use thereof as cell culture mat or guided bone regeneration shielding membrane
HK1253060A1 (en) Tissue culture apparatus and method
SG11201705853VA (en) Cell culture device and cell culture method
EP3091786A4 (en) Apparatus, method and system for cell selection
SG11201708807QA (en) Cell preservative solution, use of same, and method of producing cell preservative solution
DK3317435T3 (en) Reduction method and electrolysis system for electrochemical carbon dioxide use
EP3196292A4 (en) Cell culture apparatus and method
GB201507041D0 (en) High density soiless plant growth system and method
SG11201706009PA (en) Long-term cell-cultivation using polyimide porous membrane and cell-cryopreservation method using polyimide porous membrane
EP3105570A4 (en) Method and apparatus for cell isolation, growth, replication, manipulation, and analysis
GB201509563D0 (en) Selective electropolishing method, appartus and electrolyte
SG11201608368QA (en) Water treatment method and water treatment apparatus each using membrane
EP3050580A4 (en) Method for producing biocompatible macromolecular porous body, biocompatible macromolecular porous body, biocompatible macromolecular block and cell structure
EP3156477A4 (en) Observation device, observation method, observation system, program thereof, and method for producing cells
SG11201701562WA (en) Cell trapping method, method for producing specific cell-trapping device, and method for producing specific cell-containing solution
EP3344587A4 (en) Method and system for wastewater treatment using membrane bioreactor