SG11201705529WA - Methods and devices for breaking cell aggregation and separating or enriching cells - Google Patents

Methods and devices for breaking cell aggregation and separating or enriching cells

Info

Publication number
SG11201705529WA
SG11201705529WA SG11201705529WA SG11201705529WA SG11201705529WA SG 11201705529W A SG11201705529W A SG 11201705529WA SG 11201705529W A SG11201705529W A SG 11201705529WA SG 11201705529W A SG11201705529W A SG 11201705529WA SG 11201705529W A SG11201705529W A SG 11201705529WA
Authority
SG
Singapore
Prior art keywords
separating
methods
devices
cell aggregation
breaking cell
Prior art date
Application number
SG11201705529WA
Other languages
English (en)
Inventor
Antonio Guia
Ky Truong
Original Assignee
Aviva Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aviva Biosciences Corp filed Critical Aviva Biosciences Corp
Publication of SG11201705529WA publication Critical patent/SG11201705529WA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04Cell isolation or sorting
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/20Material Coatings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/14Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02Separating microorganisms from the culture medium; Concentration of biomass
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N15/1436Optical arrangements the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/011Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells with lysing, e.g. of erythrocytes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/016White blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201705529WA 2015-01-09 2016-01-08 Methods and devices for breaking cell aggregation and separating or enriching cells SG11201705529WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562101938P 2015-01-09 2015-01-09
PCT/US2016/012744 WO2016112349A1 (en) 2015-01-09 2016-01-08 Methods and devices for breaking cell aggregation and separating or enriching cells

Publications (1)

Publication Number Publication Date
SG11201705529WA true SG11201705529WA (en) 2017-08-30

Family

ID=56356511

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201705529WA SG11201705529WA (en) 2015-01-09 2016-01-08 Methods and devices for breaking cell aggregation and separating or enriching cells

Country Status (7)

Country Link
US (1) US20160237397A1 (de)
EP (1) EP3242929A4 (de)
CN (1) CN107614671A (de)
AU (1) AU2016205090A1 (de)
CA (1) CA2973388A1 (de)
SG (1) SG11201705529WA (de)
WO (1) WO2016112349A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11249077B2 (en) * 2016-09-30 2022-02-15 Arkray, Inc. Method for magnetically labeling particles and labeling apparatus
JP6754345B2 (ja) * 2016-09-30 2020-09-09 アークレイ株式会社 粒子の磁気標識方法及び標識装置
WO2018191534A1 (en) * 2017-04-14 2018-10-18 Aviva Biosciences Corporation Methods, compositions, and devices for separating and/or enriching cells
EP3759213A4 (de) * 2018-03-02 2022-03-16 Quantumcyte, Inc. Verfahren, zusammensetzungen und vorrichtungen zur isolierung und expressionsanalyse von interessierenden regionen aus einem gewebe
US20220260557A1 (en) * 2018-07-27 2022-08-18 Veravas, Inc. Methods for depletion and enrichment
EP3922711A4 (de) * 2019-02-05 2022-11-30 Universal Bio Research Co., Ltd. Probenbehandlungsvorrichtung
CN110680527B (zh) * 2019-09-24 2020-11-06 西安交通大学 种植体系统及微电极模块
CN111574638A (zh) * 2020-06-30 2020-08-25 上海工程技术大学 一种灵芝多糖的提取装置及提取工艺
EP4245838A1 (de) * 2020-11-11 2023-09-20 Shenzhen Huixin Life Technologies Co., Ltd Trennchip-anordnung
CN112899146B (zh) * 2021-01-27 2023-06-13 广州安方生物科技有限公司 一种全自动细胞分离系统

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994026087A2 (en) * 1993-05-14 1994-11-24 Connor Kim C O Recombinant protein production and insect cell culture and process
US6312685B1 (en) * 1998-03-13 2001-11-06 Timothy C. Fisher Red blood cells covalently bound with two different polyethylene glycol derivatives
US20140008210A1 (en) * 2012-07-06 2014-01-09 Aviva Biosciences Corporation Methods and compositions for separating or enriching cells
US7166443B2 (en) * 2001-10-11 2007-01-23 Aviva Biosciences Corporation Methods, compositions, and automated systems for separating rare cells from fluid samples
EP1715345B1 (de) * 2005-03-29 2013-12-04 Sysmex Corporation Reagens zur teilweisen Auflösung der Zellmembran einer roten Blutzelle, Reagens zur Erkennung von mit Malaria infizierten roten Blutkörperchen, und Probenanalyseverfahren zur Erkennung von mit Malaria infizierten roten Blutkörperchen.
US20060266692A1 (en) * 2005-05-25 2006-11-30 Innovative Micro Technology Microfabricated cross flow filter and method of manufacture
KR101720808B1 (ko) * 2008-12-01 2017-03-28 제너럴 일렉트릭 캄파니 세포를 체액으로부터 분리하기 위한 시스템 및 방법
JP6208473B2 (ja) * 2012-06-20 2017-10-04 アークレイ株式会社 血液成分を含む試料の処理方法
CN103509750A (zh) * 2012-06-29 2014-01-15 中国科学院大连化学物理研究所 一种分离纯化哺乳动物胰岛的方法

Also Published As

Publication number Publication date
CN107614671A (zh) 2018-01-19
WO2016112349A1 (en) 2016-07-14
AU2016205090A1 (en) 2017-07-27
EP3242929A1 (de) 2017-11-15
EP3242929A4 (de) 2018-09-05
CA2973388A1 (en) 2016-07-14
US20160237397A1 (en) 2016-08-18

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