SG11201704321TA - Stable peptide-conjugated ascorbic acid derivative, method for preparing same, and cosmetic composition comprising same - Google Patents
Stable peptide-conjugated ascorbic acid derivative, method for preparing same, and cosmetic composition comprising sameInfo
- Publication number
- SG11201704321TA SG11201704321TA SG11201704321TA SG11201704321TA SG11201704321TA SG 11201704321T A SG11201704321T A SG 11201704321TA SG 11201704321T A SG11201704321T A SG 11201704321TA SG 11201704321T A SG11201704321T A SG 11201704321TA SG 11201704321T A SG11201704321T A SG 11201704321TA
- Authority
- SG
- Singapore
- Prior art keywords
- same
- ascorbic acid
- acid derivative
- cosmetic composition
- stable peptide
- Prior art date
Links
- 125000003289 ascorbyl group Chemical class [H]O[C@@]([H])(C([H])([H])O*)[C@@]1([H])OC(=O)C(O*)=C1O* 0.000 title 1
- 239000002537 cosmetic Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
- C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/62—Three oxygen atoms, e.g. ascorbic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
- C07H11/04—Phosphates; Phosphites; Polyphosphates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20140167350 | 2014-11-27 | ||
PCT/KR2015/011218 WO2016085127A2 (en) | 2014-11-27 | 2015-10-22 | Stable peptide-conjugated ascorbic acid derivative, method for preparing same, and cosmetic composition containing same |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201704321TA true SG11201704321TA (en) | 2017-06-29 |
Family
ID=56075108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201704321TA SG11201704321TA (en) | 2014-11-27 | 2015-10-22 | Stable peptide-conjugated ascorbic acid derivative, method for preparing same, and cosmetic composition comprising same |
Country Status (8)
Country | Link |
---|---|
US (1) | US10239902B2 (en) |
EP (1) | EP3225620B1 (en) |
JP (1) | JP6500105B2 (en) |
KR (1) | KR101652204B1 (en) |
CN (1) | CN107207566B (en) |
ES (1) | ES2767412T3 (en) |
SG (1) | SG11201704321TA (en) |
WO (1) | WO2016085127A2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018005762A2 (en) * | 2016-06-29 | 2018-01-04 | Orasis Medical, Inc. | Ascorbic acid-amino acid conjugates and their use in regulation of fluid outflow |
JP6875704B2 (en) * | 2018-04-13 | 2021-05-26 | マイクロアルジェコーポレーション株式会社 | Composition for suppressing melanin production, composition for whitening, and composition for suppressing expression |
KR102130701B1 (en) * | 2018-09-27 | 2020-07-06 | 주식회사 차메디텍 | Vitamin c derivatives with a peptidemolecule and composition containing the same |
KR102222697B1 (en) | 2019-05-02 | 2021-03-04 | (주)리즈케이 | Cosmetic composition having ascorbic acid and cosmetic products having the same |
KR20220017695A (en) * | 2020-08-05 | 2022-02-14 | 주식회사 레미바이오 | Ascorbic acid derivative and composition including thereof |
CN115260170B (en) * | 2021-04-30 | 2024-05-28 | 禾美生物科技(浙江)有限公司 | Ascorbic acid polypeptide derivative and preparation method and application thereof |
KR20230149537A (en) | 2022-04-20 | 2023-10-27 | 주식회사 바른바름 | Solid lipid nanoparticles comprising 4-alkylresorcinol, cosmetic composition and cosmetics comprising the same |
KR102576447B1 (en) * | 2022-11-14 | 2023-09-08 | 주식회사 차메디텍 | Vitamin C-peptide derivatives with increased thermal stability and compositions for collagen formation, whitening, and/or antioxidant containing the same |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5409693A (en) * | 1989-10-12 | 1995-04-25 | Perricone; Nicholas V. | Method for treating and preventing sunburn and sunburn damage to the skin |
JP2772712B2 (en) * | 1990-11-15 | 1998-07-09 | 花王株式会社 | Ascorbic acid derivative and method for producing the same |
US5714484A (en) * | 1993-12-08 | 1998-02-03 | Prototek, Inc. | α-(1,3-dicarbonylenol ether) methyl ketones as cysteine protease inhibitors |
US5916915A (en) * | 1997-06-04 | 1999-06-29 | Pacific Corporation | Water-in-stable L-ascorbic acid derivative and a method for preparation thereof, and a skin-whitening cosmetic composition containing the same |
JP2001270816A (en) * | 2000-03-23 | 2001-10-02 | Ichimaru Pharcos Co Ltd | Cosmetic composition |
IL157359A0 (en) * | 2001-02-26 | 2004-02-19 | Bristol Myers Squibb Pharma Co | A radiopharmaceutical composition containing an ascorbic acid analog |
JPWO2004028484A1 (en) * | 2002-09-24 | 2006-01-19 | 株式会社坂本バイオ | Melanin production inhibitor, whitening agent, melanin production inhibiting composition and whitening composition |
KR100459679B1 (en) * | 2003-04-30 | 2004-12-03 | 주식회사 펩트론 | Vitamin C derivatives with peptide, preparation method thereof and composition comprising the same |
JPWO2007094030A1 (en) * | 2006-02-13 | 2009-07-02 | 株式会社坂本バイオ | Whitening agent |
KR100691540B1 (en) * | 2006-06-22 | 2007-03-12 | 주식회사 펩트론 | Stabilized vitamin c derivatives with a peptide molecule, preparation method thereof, and composition containing the same |
JP5255775B2 (en) * | 2007-03-15 | 2013-08-07 | ピアス株式会社 | Aqueous gel, external preparation for skin and cosmetics |
KR101413939B1 (en) * | 2007-10-20 | 2014-06-30 | 재단법인서울대학교산학협력재단 | Peptide coupled ascorbic acid derivatives |
US9408797B2 (en) * | 2011-06-03 | 2016-08-09 | Allergan, Inc. | Dermal filler compositions for fine line treatment |
-
2015
- 2015-10-22 EP EP15864076.3A patent/EP3225620B1/en active Active
- 2015-10-22 KR KR1020150147473A patent/KR101652204B1/en active IP Right Grant
- 2015-10-22 SG SG11201704321TA patent/SG11201704321TA/en unknown
- 2015-10-22 WO PCT/KR2015/011218 patent/WO2016085127A2/en active Application Filing
- 2015-10-22 ES ES15864076T patent/ES2767412T3/en active Active
- 2015-10-22 CN CN201580074463.5A patent/CN107207566B/en active Active
- 2015-10-22 JP JP2017527922A patent/JP6500105B2/en active Active
-
2017
- 2017-05-26 US US15/606,628 patent/US10239902B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
KR101652204B1 (en) | 2016-08-29 |
KR20160063976A (en) | 2016-06-07 |
ES2767412T3 (en) | 2020-06-17 |
JP2018509376A (en) | 2018-04-05 |
CN107207566B (en) | 2021-01-22 |
CN107207566A (en) | 2017-09-26 |
EP3225620A2 (en) | 2017-10-04 |
US20170258931A1 (en) | 2017-09-14 |
EP3225620B1 (en) | 2019-11-20 |
EP3225620A4 (en) | 2018-11-07 |
JP6500105B2 (en) | 2019-04-10 |
WO2016085127A3 (en) | 2016-10-06 |
WO2016085127A2 (en) | 2016-06-02 |
US10239902B2 (en) | 2019-03-26 |
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