SG11201703880VA - Triazolopyrimidine compounds and uses thereof - Google Patents
Triazolopyrimidine compounds and uses thereofInfo
- Publication number
- SG11201703880VA SG11201703880VA SG11201703880VA SG11201703880VA SG11201703880VA SG 11201703880V A SG11201703880V A SG 11201703880VA SG 11201703880V A SG11201703880V A SG 11201703880VA SG 11201703880V A SG11201703880V A SG 11201703880VA SG 11201703880V A SG11201703880V A SG 11201703880VA
- Authority
- SG
- Singapore
- Prior art keywords
- triazolopyrimidine compounds
- triazolopyrimidine
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2014094644 | 2014-12-23 | ||
| CN2015095320 | 2015-11-23 | ||
| PCT/IB2015/059843 WO2016103155A1 (en) | 2014-12-23 | 2015-12-21 | Triazolopyrimidine compounds and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201703880VA true SG11201703880VA (en) | 2017-07-28 |
Family
ID=55071101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201703880VA SG11201703880VA (en) | 2014-12-23 | 2015-12-21 | Triazolopyrimidine compounds and uses thereof |
Country Status (40)
| Country | Link |
|---|---|
| US (5) | US9580437B2 (en) |
| EP (1) | EP3237418B1 (en) |
| JP (1) | JP6736559B2 (en) |
| KR (1) | KR102534028B1 (en) |
| CN (1) | CN107108637B (en) |
| AU (1) | AU2015370524B2 (en) |
| BR (1) | BR112017010354B8 (en) |
| CA (1) | CA2969090C (en) |
| CL (1) | CL2017001572A1 (en) |
| CO (1) | CO2017005992A2 (en) |
| CR (1) | CR20170285A (en) |
| CY (1) | CY1121901T1 (en) |
| DK (1) | DK3237418T3 (en) |
| DO (1) | DOP2017000149A (en) |
| EA (1) | EA032416B1 (en) |
| EC (1) | ECSP17047153A (en) |
| ES (1) | ES2722048T3 (en) |
| GT (1) | GT201700146A (en) |
| HR (1) | HRP20190805T1 (en) |
| HU (1) | HUE043060T2 (en) |
| IL (1) | IL252135B (en) |
| JO (1) | JO3489B1 (en) |
| LT (1) | LT3237418T (en) |
| ME (1) | ME03385B (en) |
| MX (1) | MX2017008529A (en) |
| MY (1) | MY186837A (en) |
| NZ (1) | NZ731664A (en) |
| PE (1) | PE20171307A1 (en) |
| PH (1) | PH12017501016B1 (en) |
| PL (1) | PL3237418T3 (en) |
| PT (1) | PT3237418T (en) |
| RS (1) | RS58679B1 (en) |
| SG (1) | SG11201703880VA (en) |
| SI (1) | SI3237418T1 (en) |
| SV (1) | SV2017005472A (en) |
| TN (1) | TN2017000204A1 (en) |
| TW (1) | TWI694076B (en) |
| UA (1) | UA120945C2 (en) |
| UY (1) | UY36462A (en) |
| WO (1) | WO2016103155A1 (en) |
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| ES2722048T3 (en) * | 2014-12-23 | 2019-08-07 | Novartis Ag | Triazolopyrimidine compounds and uses thereof |
| AU2017273726B2 (en) * | 2016-06-01 | 2023-10-19 | Epizyme, Inc. | Use of EZH2 inhibitors for treating cancer |
| ES2798424T3 (en) * | 2016-06-20 | 2020-12-11 | Novartis Ag | Triazolopyridine Compounds and Uses of These |
| US11091489B2 (en) * | 2016-06-20 | 2021-08-17 | Novartis Ag | Crystalline forms of a triazolopyrimidine compound |
| US10676479B2 (en) | 2016-06-20 | 2020-06-09 | Novartis Ag | Imidazolepyridine compounds and uses thereof |
| IL264186B1 (en) | 2016-07-12 | 2024-04-01 | Revolution Medicines Inc | 2,5-disubstituted 3-methyl pyrazines and 2,5,6-trisubstituted 3-methyl pyrazines as allosteric shp2 inhibitors |
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| IL296456A (en) | 2017-01-23 | 2022-11-01 | Revolution Medicines Inc | Bicyclic compounds as allosteric shp2 inhibitors |
| CN110431134A (en) | 2017-01-23 | 2019-11-08 | 锐新医药公司 | Pyridine compounds as allosteric SHP2 inhibitor |
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| US10266542B2 (en) | 2017-03-15 | 2019-04-23 | Mirati Therapeutics, Inc. | EZH2 inhibitors |
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| WO2019062435A1 (en) * | 2017-09-28 | 2019-04-04 | 中国科学院上海药物研究所 | Use of triazolopyrimidine, triazolopyridine compounds and composition thereof for treating prc2-mediated diseases |
| CN109575013A (en) * | 2017-09-28 | 2019-04-05 | 中国科学院上海药物研究所 | Triazole and pyrimidine, triazole and pyridine compounds and combinations thereof are for treating the disease of PRC2 mediation |
| BR112020007058A2 (en) | 2017-10-12 | 2020-10-06 | Revolution Medicines, Inc. | pyridine, pyrazine, and triazine compounds as allosteric shp2 inhibitors |
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| CN112004816B (en) | 2018-01-31 | 2024-01-05 | 米拉蒂医疗股份有限公司 | PRC2 inhibitors |
| CN110156787B (en) * | 2018-02-13 | 2021-11-02 | 中国科学院上海药物研究所 | Triazole pyrimidine derivative compound, pharmaceutical composition containing triazole pyrimidine derivative compound and application of triazole pyrimidine derivative compound |
| CN110563722A (en) * | 2018-06-06 | 2019-12-13 | 上海青煜医药科技有限公司 | pyridine or pyridazine ring compound and application thereof |
| CN110734436A (en) * | 2018-07-19 | 2020-01-31 | 上海青煜医药科技有限公司 | Pyrimidine or pyrazine ring compounds and application thereof |
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2015
- 2015-12-21 ES ES15820637T patent/ES2722048T3/en active Active
- 2015-12-21 CN CN201580070691.5A patent/CN107108637B/en active Active
- 2015-12-21 MY MYPI2017701623A patent/MY186837A/en unknown
- 2015-12-21 CA CA2969090A patent/CA2969090C/en active Active
- 2015-12-21 CR CR20170285A patent/CR20170285A/en unknown
- 2015-12-21 JP JP2017533767A patent/JP6736559B2/en active Active
- 2015-12-21 ME MEP-2019-127A patent/ME03385B/en unknown
- 2015-12-21 PT PT15820637T patent/PT3237418T/en unknown
- 2015-12-21 EP EP15820637.5A patent/EP3237418B1/en active Active
- 2015-12-21 NZ NZ731664A patent/NZ731664A/en unknown
- 2015-12-21 US US14/977,273 patent/US9580437B2/en active Active
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