SG11201702997YA - Therapeutic hpv16 vaccines - Google Patents

Therapeutic hpv16 vaccines

Info

Publication number
SG11201702997YA
SG11201702997YA SG11201702997YA SG11201702997YA SG11201702997YA SG 11201702997Y A SG11201702997Y A SG 11201702997YA SG 11201702997Y A SG11201702997Y A SG 11201702997YA SG 11201702997Y A SG11201702997Y A SG 11201702997YA SG 11201702997Y A SG11201702997Y A SG 11201702997YA
Authority
SG
Singapore
Prior art keywords
therapeutic
vaccines
hpv16 vaccines
therapeutic hpv16
hpv16
Prior art date
Application number
SG11201702997YA
Inventor
Evelien M Bunnik
Jerôme H H V Custers
Gerrit Ch Scheper
Koen Oosterhuis
Taco Gilles Uil
Selina Khan
Original Assignee
Janssen Vaccines & Prevention Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52020908&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201702997Y(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Vaccines & Prevention Bv filed Critical Janssen Vaccines & Prevention Bv
Publication of SG11201702997YA publication Critical patent/SG11201702997YA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01—DNA viruses
    • C07K14/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10041—Use of virus, viral particle or viral elements as a vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20071—Demonstrated in vivo effect
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/106—Plasmid DNA for vertebrates
    • C12N2800/107—Plasmid DNA for vertebrates for mammalian
SG11201702997YA 2014-11-04 2015-11-03 Therapeutic hpv16 vaccines SG11201702997YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14191660 2014-11-04
PCT/EP2015/075516 WO2016071306A1 (en) 2014-11-04 2015-11-03 Therapeutic hpv16 vaccines

Publications (1)

Publication Number Publication Date
SG11201702997YA true SG11201702997YA (en) 2017-05-30

Family

ID=52020908

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201702997YA SG11201702997YA (en) 2014-11-04 2015-11-03 Therapeutic hpv16 vaccines

Country Status (33)

Country Link
US (4) US9701721B2 (en)
EP (2) EP3215187B1 (en)
JP (2) JP6325751B2 (en)
KR (1) KR20170083562A (en)
CN (1) CN107075521B (en)
AR (1) AR102527A1 (en)
AU (2) AU2015341926B2 (en)
BR (1) BR112017009177A2 (en)
CA (1) CA2965562C (en)
CL (1) CL2017001089A1 (en)
CO (1) CO2017004838A2 (en)
CY (1) CY1121377T1 (en)
DK (1) DK3215187T3 (en)
EA (1) EA035461B1 (en)
ES (1) ES2697903T3 (en)
HR (1) HRP20181895T1 (en)
HU (1) HUE040440T2 (en)
IL (1) IL251895B (en)
LT (1) LT3215187T (en)
MA (2) MA40902B1 (en)
MD (1) MD3215187T2 (en)
MX (1) MX2017005788A (en)
MY (1) MY181175A (en)
NZ (1) NZ730802A (en)
PL (1) PL3215187T3 (en)
PT (1) PT3215187T (en)
RS (1) RS58080B1 (en)
SA (1) SA517381457B1 (en)
SG (1) SG11201702997YA (en)
SI (1) SI3215187T1 (en)
TW (2) TWI731654B (en)
WO (1) WO2016071306A1 (en)
ZA (1) ZA201703055B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016071306A1 (en) 2014-11-04 2016-05-12 Crucell Holland B.V. Therapeutic hpv16 vaccines
BR112018003019A2 (en) 2015-08-20 2018-09-25 Janssen Vaccines & Prevention Bv hpv18 therapeutic vaccines
CN109922829A (en) * 2016-05-02 2019-06-21 扬森疫苗与预防公司 Therapeutic HPV vaccine combination
CN106632694B (en) * 2017-01-24 2021-02-12 南京益康生物医药有限公司 Recombinant protein, pharmaceutical composition and application
EA202090628A1 (en) * 2017-09-23 2020-11-16 Бёрингер Ингельхайм Ветмедика Гмбх PARAMYXOVIRIDAE EXPRESSION SYSTEM
US20200399348A1 (en) * 2018-02-20 2020-12-24 Emory University HPV Proteins, Antibodies, and Uses in Managing Abnormal Epithelial Cell Growth
CR20200461A (en) * 2018-03-12 2021-03-11 Sqz Biotechnologies Co Methods for treating hpv-associated diseases
EP3810277A1 (en) * 2018-07-20 2021-04-28 Janssen Vaccines & Prevention B.V. Recombinant adenoviral vector expressing zika antigen with improved productivity
CN108992665B (en) * 2018-08-06 2021-11-19 南京颂悦生物科技有限公司 Cervical cancer therapeutic vaccine based on recombinant attenuated listeria monocytogenes
CN108939064B (en) * 2018-08-06 2021-12-10 南京颂悦生物科技有限公司 Cervical cancer therapeutic vaccine based on recombinant attenuated sheep listeria
EP3935581A4 (en) 2019-03-04 2022-11-30 Iocurrents, Inc. Data compression and communication using machine learning
EP4031573A1 (en) 2019-09-20 2022-07-27 Transgene Combination of a poxvirus encoding hpv polypeptides and il-2 with an anti-pd-l1 antibody
WO2021202949A2 (en) * 2020-04-02 2021-10-07 Inovio Pharmaceuticals, Inc. Compositions and methods for treating vulvar dysplasia
WO2021209897A1 (en) 2020-04-13 2021-10-21 Janssen Biotech, Inc. Psma and steap1 vaccines and their uses
WO2021228816A1 (en) * 2020-05-12 2021-11-18 Janssen Vaccines & Prevention B.V. Administration of homologous adenoviral vectors
WO2022115490A2 (en) * 2020-11-24 2022-06-02 MA, Muchou, Joe Dna vaccine for human palillomavirus and method for using the same
WO2023070109A1 (en) * 2021-10-22 2023-04-27 Inovio Pharmaceuticals, Inc. Compositions and methods for treating anal high-grade squamous intraepithelial lesion (hsil)

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3584341D1 (en) 1984-08-24 1991-11-14 Upjohn Co RECOMBINANT DNA COMPOUNDS AND EXPRESSION OF POLYPEPTIDES LIKE TPA.
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
NZ230747A (en) 1988-09-30 1992-05-26 Bror Morein Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina
WO1990014837A1 (en) 1989-05-25 1990-12-13 Chiron Corporation Adjuvant formulation comprising a submicron oil droplet emulsion
FR2705686B1 (en) 1993-05-28 1995-08-18 Transgene Sa New defective adenoviruses and corresponding complementation lines.
DE69535178T2 (en) 1994-06-10 2006-12-14 Genvec, Inc. ADENOVER VECTOR SYSTEMS AND CELL LINES
US5851806A (en) 1994-06-10 1998-12-22 Genvec, Inc. Complementary adenoviral systems and cell lines
US5846782A (en) 1995-11-28 1998-12-08 Genvec, Inc. Targeting adenovirus with use of constrained peptide motifs
US5965541A (en) 1995-11-28 1999-10-12 Genvec, Inc. Vectors and methods for gene transfer to cells
US5559099A (en) 1994-09-08 1996-09-24 Genvec, Inc. Penton base protein and methods of using same
US5786464C1 (en) 1994-09-19 2012-04-24 Gen Hospital Corp Overexpression of mammalian and viral proteins
AUPM873294A0 (en) 1994-10-12 1994-11-03 Csl Limited Saponin preparations and use thereof in iscoms
DE69638058D1 (en) 1995-06-15 2009-11-26 Crucell Holland Bv Packaging systems for human recombinant adenoviruses for gene therapy
US5837511A (en) 1995-10-02 1998-11-17 Cornell Research Foundation, Inc. Non-group C adenoviral vectors
US5891690A (en) 1996-04-26 1999-04-06 Massie; Bernard Adenovirus E1-complementing cell lines
WO1998039411A1 (en) 1997-03-04 1998-09-11 Baxter International Inc. Adenovirus e1-complementing cell lines
US6020191A (en) 1997-04-14 2000-02-01 Genzyme Corporation Adenoviral vectors capable of facilitating increased persistence of transgene expression
US5972650A (en) 1997-06-26 1999-10-26 Brigham And Women's Hospital Tetracycline repressor regulated mammalian cell transcription and viral replication switch
US5981225A (en) 1998-04-16 1999-11-09 Baylor College Of Medicine Gene transfer vector, recombinant adenovirus particles containing the same, method for producing the same and method of use of the same
US6113913A (en) 1998-06-26 2000-09-05 Genvec, Inc. Recombinant adenovirus
PT1054064E (en) 1999-05-17 2005-02-28 Crucell Holland Bv DELIVERY VEHICLES OF ADENOVIRUS-DERIVED GENES COMPREHENSING AT LEAST ONE ADENOVIRUS ELEMENT OF TYPE 35
US6913922B1 (en) 1999-05-18 2005-07-05 Crucell Holland B.V. Serotype of adenovirus and uses thereof
FR2794370B1 (en) 1999-06-03 2003-10-17 Biovector Therapeutics POLYEPITOPIC PROTEIN FRAGMENTS, THEIR OBTAINMENT AND THEIR USES IN PARTICULAR IN VACCINATION
WO2001019408A1 (en) * 1999-09-16 2001-03-22 Zycos Inc. Nucleic acids encoding polyepitope polypeptides
DE19955558C2 (en) 1999-11-18 2003-03-20 Stefan Kochanek Permanent amniocyte cell line, its production and use for the production of gene transfer vectors
AU2002211524B2 (en) 2000-10-04 2007-03-22 The Trustees Of The University Of Pennsylvania Highly expressible genes
UA76731C2 (en) 2000-11-23 2006-09-15 Баваріан Нордік А/С Mva-bn strain of modified vaccinia ankara virus, pharmaceutical composition, vaccine, use of mva-bn strain for vaccine preparation, method for transfer of homologous and/or heterologous nucleic acid sequence into the target cells in vitro, method for preparing peptide or protein, method for obtaining mva-bn strain, host cell, set for primary/buster immunization
US7745592B2 (en) 2001-05-01 2010-06-29 National Research Council Of Canada Cumate-inducible expression system for eukaryotic cells
IL164803A0 (en) 2002-04-25 2005-12-18 Crucell Holland Bv Means and methods for the production of adenovirusvectors
SE0202110D0 (en) 2002-07-05 2002-07-05 Isconova Ab Iscom preparation and use thereof
SE0301998D0 (en) 2003-07-07 2003-07-07 Isconova Ab Quil A fraction with low toxicity and use thereof
US20070014810A1 (en) * 2003-12-31 2007-01-18 Denise Baker Inducing cellular immune responses to human papillomavirus using peptide and nucleic acid compositions
AU2005214090B2 (en) 2004-02-23 2008-09-11 Crucell Holland B.V. Virus purification methods
KR101271884B1 (en) 2004-11-08 2013-06-05 크로마제닉스 비.브이. Selection of host cells expressing protein at high levels
WO2007073513A2 (en) 2005-11-10 2007-06-28 Genvec, Inc. Method for propagating adenoviral vectors encoding inhibitory gene products
AU2007220988B2 (en) 2006-02-28 2010-06-03 Vaxart, Inc Chimeric adenoviral vectors
WO2007104792A2 (en) 2006-03-16 2007-09-20 Crucell Holland B.V. Recombinant adenoviruses based on serotype 26 and 48, and use thereof
JP5474567B2 (en) * 2007-01-30 2014-04-16 トランジェーヌ、ソシエテ、アノニム Papillomavirus vaccine
DE102008010954A1 (en) * 2008-02-25 2009-08-27 Cichon, Günter, Prof.Dr. DNA vaccine for the therapy and prophylaxis of cervical cancer and its premalignant precursors
JP5770633B2 (en) 2008-11-03 2015-08-26 クルセル ホランド ベー ヴェー Method for producing adenovirus vector
GB0823497D0 (en) 2008-12-24 2009-01-28 Isis Innovation Immunogenic composition and use thereof
EP2536829B1 (en) 2010-02-15 2016-04-06 Crucell Holland B.V. Method for the production of Ad26 adenoviral vectors
PL2604629T3 (en) * 2010-08-13 2018-08-31 Genexine, Inc. Composition for preventing or treating cervical cancer having human papillomavirus immunity enhancer
US20130122038A1 (en) 2011-11-14 2013-05-16 The United States Of America As Represented By The Secretary Of The Department Heterologous prime-boost immunization using measles virus-based vaccines
EP2601968A1 (en) * 2011-12-06 2013-06-12 Deutsches Krebsforschungszentrum HPV derived polynucleic acids for therapy
US8932607B2 (en) 2012-03-12 2015-01-13 Crucell Holland B.V. Batches of recombinant adenovirus with altered terminal ends
US9125870B2 (en) 2012-03-22 2015-09-08 Crucell Holland B.V. Vaccine against RSV
CN112972668A (en) 2014-09-03 2021-06-18 巴法里安诺迪克有限公司 Recombinant modified vaccinia virus ankara (MVA) filovirus vaccine
WO2016071306A1 (en) 2014-11-04 2016-05-12 Crucell Holland B.V. Therapeutic hpv16 vaccines
BR112018003019A2 (en) * 2015-08-20 2018-09-25 Janssen Vaccines & Prevention Bv hpv18 therapeutic vaccines
CN109922829A (en) * 2016-05-02 2019-06-21 扬森疫苗与预防公司 Therapeutic HPV vaccine combination

Also Published As

Publication number Publication date
SA517381457B1 (en) 2021-03-11
AU2018282463A1 (en) 2019-01-24
EP3215187B1 (en) 2018-08-29
RS58080B1 (en) 2019-02-28
AU2015341926A1 (en) 2017-04-27
IL251895B (en) 2019-08-29
MX2017005788A (en) 2017-08-02
SI3215187T1 (en) 2019-02-28
HRP20181895T1 (en) 2019-01-11
US20180344841A1 (en) 2018-12-06
MA46378A (en) 2019-08-07
US20170281747A1 (en) 2017-10-05
CL2017001089A1 (en) 2017-12-29
TW202043476A (en) 2020-12-01
MY181175A (en) 2020-12-21
CY1121377T1 (en) 2020-05-29
US11040096B2 (en) 2021-06-22
IL251895A0 (en) 2017-06-29
CA2965562A1 (en) 2016-05-12
EP3215187A1 (en) 2017-09-13
LT3215187T (en) 2018-12-27
US20160122396A1 (en) 2016-05-05
AR102527A1 (en) 2017-03-08
AU2015341926B2 (en) 2018-09-27
HUE040440T2 (en) 2019-03-28
KR20170083562A (en) 2017-07-18
PL3215187T3 (en) 2019-04-30
CN107075521B (en) 2021-06-08
AU2018282463B2 (en) 2020-09-10
US10071151B2 (en) 2018-09-11
ES2697903T3 (en) 2019-01-29
MA40902B1 (en) 2018-12-31
CN107075521A (en) 2017-08-18
CA2965562C (en) 2023-11-21
TWI694147B (en) 2020-05-21
TW201617450A (en) 2016-05-16
NZ730802A (en) 2021-12-24
WO2016071306A1 (en) 2016-05-12
US10555996B2 (en) 2020-02-11
EA201790976A1 (en) 2017-09-29
US9701721B2 (en) 2017-07-11
JP6325751B2 (en) 2018-05-16
PT3215187T (en) 2018-11-27
ZA201703055B (en) 2019-11-27
BR112017009177A2 (en) 2018-12-11
MD3215187T2 (en) 2019-02-28
EP3421046A1 (en) 2019-01-02
JP2017534286A (en) 2017-11-24
TWI731654B (en) 2021-06-21
JP6606571B2 (en) 2019-11-13
CO2017004838A2 (en) 2017-07-28
MA40902A (en) 2017-09-13
US20200164057A1 (en) 2020-05-28
JP2018148890A (en) 2018-09-27
EA035461B1 (en) 2020-06-19
DK3215187T3 (en) 2018-12-10

Similar Documents

Publication Publication Date Title
HRP20181895T1 (en) Therapeutic hpv16 vaccines
ZA201904717B (en) Therapeutic hpv18 vaccines
HK1246183A1 (en) Hpv vaccines
PT3132034T (en) Therapeutic
GB201410971D0 (en) Vaccine
GB201518684D0 (en) Vaccine
PL3185899T3 (en) Improved hvt-vectored nd-ibd vaccine
ZA201808121B (en) Therapeutic hpv vaccine combinations
IL247159B (en) Pcsk9 vaccines
GB201410216D0 (en) Therapeutic
GB201522132D0 (en) Vaccine
GB201510637D0 (en) Therapeutic
HK1248560A1 (en) Dna-peptide combination vaccine
LT3188755T (en) Vaccine
GB201417214D0 (en) Vaccine
GB201406628D0 (en) Vaccine
GB201418508D0 (en) Therapeutic
GB201413719D0 (en) Therapeutic
GB201410832D0 (en) Therapeutic
GB201410334D0 (en) Therapeutic
GB201415302D0 (en) New therapeutic use
GB201406674D0 (en) Therapeutic