SG11201702469TA - Compositions and methods for the treatment and prophylaxis of surgical site infections - Google Patents

Compositions and methods for the treatment and prophylaxis of surgical site infections

Info

Publication number
SG11201702469TA
SG11201702469TA SG11201702469TA SG11201702469TA SG11201702469TA SG 11201702469T A SG11201702469T A SG 11201702469TA SG 11201702469T A SG11201702469T A SG 11201702469TA SG 11201702469T A SG11201702469T A SG 11201702469TA SG 11201702469T A SG11201702469T A SG 11201702469TA
Authority
SG
Singapore
Prior art keywords
prophylaxis
compositions
treatment
methods
surgical site
Prior art date
Application number
SG11201702469TA
Inventor
Noam Emanuel
Original Assignee
Polypid Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55629498&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201702469T(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Polypid Ltd filed Critical Polypid Ltd
Publication of SG11201702469TA publication Critical patent/SG11201702469TA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/80Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/849Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/148Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
SG11201702469TA 2014-10-02 2015-09-27 Compositions and methods for the treatment and prophylaxis of surgical site infections SG11201702469TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462058809P 2014-10-02 2014-10-02
PCT/IB2015/057409 WO2016051321A1 (en) 2014-10-02 2015-09-27 Compositions and methods for the treatment and prophylaxis of surgical site infections

Publications (1)

Publication Number Publication Date
SG11201702469TA true SG11201702469TA (en) 2017-04-27

Family

ID=55629498

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202012452UA SG10202012452UA (en) 2014-10-02 2015-09-27 Compositions and methods for the treatment and prophylaxis of surgical site infections
SG11201702469TA SG11201702469TA (en) 2014-10-02 2015-09-27 Compositions and methods for the treatment and prophylaxis of surgical site infections

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10202012452UA SG10202012452UA (en) 2014-10-02 2015-09-27 Compositions and methods for the treatment and prophylaxis of surgical site infections

Country Status (26)

Country Link
US (3) US20170246112A1 (en)
EP (2) EP4094783A1 (en)
JP (2) JP6899767B2 (en)
KR (2) KR20230175331A (en)
CN (2) CN116473946A (en)
AU (1) AU2015326428B2 (en)
BR (1) BR112017006406B1 (en)
CA (1) CA2963370C (en)
CY (1) CY1124795T1 (en)
DK (1) DK3200748T3 (en)
EA (1) EA201790383A1 (en)
ES (1) ES2900816T3 (en)
HR (1) HRP20211880T1 (en)
HU (1) HUE056523T2 (en)
IL (1) IL251351B (en)
LT (1) LT3200748T (en)
MX (1) MX2017004318A (en)
NZ (1) NZ729619A (en)
PH (1) PH12017500569A1 (en)
PL (1) PL3200748T3 (en)
PT (1) PT3200748T (en)
RS (1) RS62696B1 (en)
SG (2) SG10202012452UA (en)
SI (1) SI3200748T1 (en)
WO (1) WO2016051321A1 (en)
ZA (1) ZA201702884B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE48948E1 (en) 2008-04-18 2022-03-01 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable polymer
EA201790383A1 (en) * 2014-10-02 2017-09-29 Полипид Лтд. COMPOSITIONS AND METHODS OF TREATMENT AND PREVENTION OF INFECTIONS OF SURGERY INTERVENTION
WO2017179996A1 (en) * 2016-04-11 2017-10-19 Aroa Biosurgery Limited Collagen-based device having antifungal properties
CN107929796A (en) * 2017-12-11 2018-04-20 河南亚都实业有限公司 Biological hemostatic film
CN108264373A (en) * 2018-02-06 2018-07-10 付主枝 The preparation method of medical reinforced porous biological ceramic material
CN113134116B (en) * 2020-01-20 2022-09-06 山东威高宏瑞医学科技有限公司 Filling composition and filling preparation for endoscopic minimally invasive surgery
CN113456897A (en) * 2020-03-31 2021-10-01 威斯顿股份有限公司 Biomaterials and their use for promoting tissue regeneration
KR20240003296A (en) 2022-06-30 2024-01-08 주식회사 티온랩테라퓨틱스 Long-acting antibiotic for treatment of diabetic foot and surgical site infection

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040087520A1 (en) * 2002-10-25 2004-05-06 Chowdhury Dipak K. Compositions and methods for delivery of therapeutic agents
US8277831B2 (en) * 2004-02-17 2012-10-02 Advanced Technologies And Regenerative Medicine, Llc. Drug-enhanced adhesion prevention
ES2630805T3 (en) 2008-07-14 2017-08-24 Polypid Ltd. Sustained release drug vehicle composition
US9248159B2 (en) 2008-10-14 2016-02-02 Robert Stanley Berman MRSA bactericidal topical gel
US9839628B2 (en) 2009-06-01 2017-12-12 Tyrx, Inc. Compositions and methods for preventing sternal wound infections
WO2011007353A1 (en) * 2009-07-14 2011-01-20 Polypid Ltd. Sustained-release drug carrier composition
US8449916B1 (en) 2009-11-06 2013-05-28 Iowa State University Research Foundation, Inc. Antimicrobial compositions and methods
US8795726B2 (en) * 2010-01-19 2014-08-05 Polypid Ltd. Sustained-release nucleic acid matrix compositions
US9173976B2 (en) * 2012-08-02 2015-11-03 Polypid Ltd. Compositions and methods for the treatment of bone voids and open fractures
EA201790383A1 (en) * 2014-10-02 2017-09-29 Полипид Лтд. COMPOSITIONS AND METHODS OF TREATMENT AND PREVENTION OF INFECTIONS OF SURGERY INTERVENTION

Also Published As

Publication number Publication date
WO2016051321A1 (en) 2016-04-07
US20220395462A1 (en) 2022-12-15
KR20230175331A (en) 2023-12-29
EA201790383A1 (en) 2017-09-29
IL251351B (en) 2022-04-01
US20200268669A1 (en) 2020-08-27
CY1124795T1 (en) 2022-11-25
JP6899767B2 (en) 2021-07-07
JP2017534585A (en) 2017-11-24
IL251351A0 (en) 2017-05-29
US11471414B2 (en) 2022-10-18
BR112017006406A2 (en) 2017-12-19
DK3200748T3 (en) 2021-12-13
EP3200748A1 (en) 2017-08-09
LT3200748T (en) 2021-12-10
AU2015326428B2 (en) 2020-12-17
PT3200748T (en) 2021-12-27
CN106999356A (en) 2017-08-01
HUE056523T2 (en) 2022-02-28
JP7046237B2 (en) 2022-04-01
AU2015326428A1 (en) 2017-03-23
ES2900816T3 (en) 2022-03-18
CA2963370C (en) 2023-04-25
EP4094783A1 (en) 2022-11-30
EP3200748B1 (en) 2021-10-27
CA2963370A1 (en) 2016-04-07
RS62696B1 (en) 2022-01-31
CN116473946A (en) 2023-07-25
SG10202012452UA (en) 2021-01-28
SI3200748T1 (en) 2022-01-31
JP2021063123A (en) 2021-04-22
PH12017500569A1 (en) 2017-08-30
HRP20211880T1 (en) 2022-03-04
EP3200748A4 (en) 2018-05-23
BR112017006406B1 (en) 2021-06-08
US20170246112A1 (en) 2017-08-31
PL3200748T3 (en) 2022-02-07
MX2017004318A (en) 2017-05-19
KR20170063638A (en) 2017-06-08
ZA201702884B (en) 2018-04-25
NZ729619A (en) 2022-12-23

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