SG11201700995WA - Crystalline forms of an estrogen receptor modulator - Google Patents

Crystalline forms of an estrogen receptor modulator

Info

Publication number
SG11201700995WA
SG11201700995WA SG11201700995WA SG11201700995WA SG11201700995WA SG 11201700995W A SG11201700995W A SG 11201700995WA SG 11201700995W A SG11201700995W A SG 11201700995WA SG 11201700995W A SG11201700995W A SG 11201700995WA SG 11201700995W A SG11201700995W A SG 11201700995WA
Authority
SG
Singapore
Prior art keywords
estrogen receptor
crystalline forms
receptor modulator
modulator
crystalline
Prior art date
Application number
SG11201700995WA
Inventor
Mark R Herbert
Nicholas D Smith
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SG11201700995WA publication Critical patent/SG11201700995WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201700995WA 2014-08-11 2015-08-10 Crystalline forms of an estrogen receptor modulator SG11201700995WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462036015P 2014-08-11 2014-08-11
PCT/EP2015/068327 WO2016023847A1 (en) 2014-08-11 2015-08-10 Crystalline forms of an estrogen receptor modulator

Publications (1)

Publication Number Publication Date
SG11201700995WA true SG11201700995WA (en) 2017-03-30

Family

ID=54011696

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201700995WA SG11201700995WA (en) 2014-08-11 2015-08-10 Crystalline forms of an estrogen receptor modulator

Country Status (15)

Country Link
US (1) US9783503B2 (en)
EP (1) EP3180316A1 (en)
JP (1) JP2017524009A (en)
KR (1) KR20170040251A (en)
CN (1) CN106660969A (en)
AR (1) AR101487A1 (en)
AU (1) AU2015303297A1 (en)
BR (1) BR112016029604A2 (en)
CA (1) CA2949329A1 (en)
IL (1) IL249160A0 (en)
MX (1) MX2017001869A (en)
RU (1) RU2017105840A (en)
SG (1) SG11201700995WA (en)
WO (1) WO2016023847A1 (en)
ZA (1) ZA201608000B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108137511A (en) 2015-10-07 2018-06-08 豪夫迈·罗氏有限公司 Prepare (E) -3- (4- ((E) -2- (the chloro- 4- fluorophenyls of 2-) -1- (1H- indazole -5- bases) but-1-ene -1- bases) phenyl) acrylic acid
CN107973780B (en) * 2016-10-21 2020-10-09 四川科伦博泰生物医药股份有限公司 Substituted olefin compound and preparation method and application thereof
US20220017463A1 (en) * 2018-11-28 2022-01-20 Luoxin Pharmaceutical (Shanghai) Co., Ltd. Salt Form of Estrogen Receptor Downregulator, Crystalline Form Thereof, and Preparation Method Therefor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1667791A1 (en) * 2003-10-06 2006-06-14 Solvias AG Process for the parallel detection of crystalline forms of molecular solids
GB2483736B (en) * 2010-09-16 2012-08-29 Aragon Pharmaceuticals Inc Estrogen receptor modulators and uses thereof
JP6154887B2 (en) 2012-03-20 2017-06-28 セラゴン ファーマシューティカルズ,インク. Estrogen receptor modulators and uses thereof
MX2015011132A (en) 2013-03-14 2015-11-30 Seragon Pharmaceuticals Inc Polycyclic estrogen receptor modulators and uses thereof.
SG11201604501TA (en) 2013-12-06 2016-07-28 Hoffmann La Roche Estrogen receptor modulator for the treatment of locally advanced or metastatic estrogen receptor positive breast cancer
MA39740A (en) 2014-03-13 2017-01-18 Hoffmann La Roche Methods and compositions for modulating estrogen receptor mutants
MA39741A (en) 2014-03-13 2017-01-18 Hoffmann La Roche Therapeutic combinations with estrogen receptor modulators

Also Published As

Publication number Publication date
AR101487A1 (en) 2016-12-21
RU2017105840A (en) 2018-09-13
EP3180316A1 (en) 2017-06-21
US20160039770A1 (en) 2016-02-11
AU2015303297A1 (en) 2016-12-01
BR112016029604A2 (en) 2017-08-22
KR20170040251A (en) 2017-04-12
US9783503B2 (en) 2017-10-10
CN106660969A (en) 2017-05-10
JP2017524009A (en) 2017-08-24
CA2949329A1 (en) 2016-02-18
WO2016023847A1 (en) 2016-02-18
IL249160A0 (en) 2017-01-31
MX2017001869A (en) 2017-05-17
ZA201608000B (en) 2017-09-27

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