SG11201610588UA - SUCCINATE DEHYDROGENASE INHIBITORS (SDHi's) - Google Patents
SUCCINATE DEHYDROGENASE INHIBITORS (SDHi's)Info
- Publication number
- SG11201610588UA SG11201610588UA SG11201610588UA SG11201610588UA SG11201610588UA SG 11201610588U A SG11201610588U A SG 11201610588UA SG 11201610588U A SG11201610588U A SG 11201610588UA SG 11201610588U A SG11201610588U A SG 11201610588UA SG 11201610588U A SG11201610588U A SG 11201610588UA
- Authority
- SG
- Singapore
- Prior art keywords
- sdhi
- succinate dehydrogenase
- dehydrogenase inhibitors
- inhibitors
- succinate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1411937.4A GB201411937D0 (en) | 2014-07-03 | 2014-07-03 | Succinate dehydrogenase inhibitors (SDH's) |
| PCT/GB2015/051949 WO2016001686A1 (en) | 2014-07-03 | 2015-07-03 | SUCCINATE DEHYDROGENASE INHIBITORS (SDHi's) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201610588UA true SG11201610588UA (en) | 2017-01-27 |
Family
ID=51410633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201610588UA SG11201610588UA (en) | 2014-07-03 | 2015-07-03 | SUCCINATE DEHYDROGENASE INHIBITORS (SDHi's) |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10603298B2 (en) |
| EP (1) | EP3164126B1 (en) |
| JP (1) | JP2017519020A (en) |
| CN (1) | CN106714793B (en) |
| AU (1) | AU2015282424A1 (en) |
| CA (1) | CA2953709A1 (en) |
| GB (1) | GB201411937D0 (en) |
| SG (1) | SG11201610588UA (en) |
| WO (1) | WO2016001686A1 (en) |
| ZA (1) | ZA201608844B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019139831A1 (en) * | 2018-01-10 | 2019-07-18 | Dana-Farber Cancer Institute, Inc. | Methods for identification, assessment, prevention, and treatment of metabolic disorders using succinate |
| CN112739418A (en) * | 2018-08-21 | 2021-04-30 | 美国卫生与公众服务部 | Methods of mitochondrial metabolic regulation using DSH inhibitors for the treatment of nerve injury and neurological disorders |
| CN109793760B (en) * | 2019-02-13 | 2022-07-19 | 中国人民解放军总医院 | Application of vibrio succinogenes in preparation of medicines for preventing or treating altitude diseases |
| GB201918022D0 (en) | 2019-12-09 | 2020-01-22 | Cambridge Entpr Ltd | Treatment or prevention of Ischaemic Stroke Reperfusion Injury |
| US11813239B2 (en) * | 2020-02-18 | 2023-11-14 | Wisconsin Alumni Research Foundation | Compositions and methods for improving cardiac structure and/or function |
| GB202108594D0 (en) | 2021-06-16 | 2021-07-28 | Cambridge Entpr Ltd | Treatment or prevention of ischaemia reperfusion injury |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU760140B2 (en) * | 1997-10-24 | 2003-05-08 | John P. Blass | Nutritional supplement for cerebral metabolic insufficiencies |
| JP2007510734A (en) * | 2003-11-07 | 2007-04-26 | ザ ヘンリー エム． ジャクソン ファウンデイション | Activation of hypoxia-inducible gene expression |
| EP2066680B1 (en) | 2006-09-28 | 2012-08-08 | Medical Research Council | Triphenylphosphonium thionitrite nitric oxide donors |
| WO2011156181A1 (en) * | 2010-06-08 | 2011-12-15 | Montefiore Medical Center | Methods and compositions for treating conditions mediated by oxidative stress or electrophilic environmental toxins |
| US9931313B2 (en) * | 2012-04-04 | 2018-04-03 | Beth Israel Deaconess Medical Center, Inc. | Methods of treating proliferative disorders with malate or derivatives thereof |
| US20140128352A1 (en) * | 2012-09-20 | 2014-05-08 | Buck Institute For Research On Aging | Compounds and methods for modulating mitochondrial metabolism and reactive oxygen species production |
| WO2014179187A1 (en) * | 2013-04-29 | 2014-11-06 | Montefiore Medical Center | Methods and compositions for preventing and treating electrophile-mediated toxicities |
-
2014
- 2014-07-03 GB GBGB1411937.4A patent/GB201411937D0/en not_active Ceased
-
2015
- 2015-07-03 SG SG11201610588UA patent/SG11201610588UA/en unknown
- 2015-07-03 CN CN201580035346.8A patent/CN106714793B/en not_active Expired - Fee Related
- 2015-07-03 US US15/322,939 patent/US10603298B2/en active Active
- 2015-07-03 CA CA2953709A patent/CA2953709A1/en not_active Abandoned
- 2015-07-03 EP EP15736028.0A patent/EP3164126B1/en active Active
- 2015-07-03 AU AU2015282424A patent/AU2015282424A1/en not_active Abandoned
- 2015-07-03 JP JP2016574359A patent/JP2017519020A/en active Pending
- 2015-07-03 WO PCT/GB2015/051949 patent/WO2016001686A1/en active Application Filing
-
2016
- 2016-12-21 ZA ZA2016/08844A patent/ZA201608844B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20170135977A1 (en) | 2017-05-18 |
| GB201411937D0 (en) | 2014-08-20 |
| AU2015282424A1 (en) | 2017-01-12 |
| EP3164126B1 (en) | 2021-02-24 |
| CA2953709A1 (en) | 2016-01-07 |
| US10603298B2 (en) | 2020-03-31 |
| JP2017519020A (en) | 2017-07-13 |
| CN106714793B (en) | 2020-12-01 |
| EP3164126A1 (en) | 2017-05-10 |
| CN106714793A (en) | 2017-05-24 |
| WO2016001686A1 (en) | 2016-01-07 |
| ZA201608844B (en) | 2019-04-24 |
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