SG11201609389QA - Diagnostic test and treatment/prevention of alzheimer's disease - Google Patents

Diagnostic test and treatment/prevention of alzheimer's disease

Info

Publication number
SG11201609389QA
SG11201609389QA SG11201609389QA SG11201609389QA SG11201609389QA SG 11201609389Q A SG11201609389Q A SG 11201609389QA SG 11201609389Q A SG11201609389Q A SG 11201609389QA SG 11201609389Q A SG11201609389Q A SG 11201609389QA SG 11201609389Q A SG11201609389Q A SG 11201609389QA
Authority
SG
Singapore
Prior art keywords
alzheimer
disease
prevention
treatment
diagnostic test
Prior art date
Application number
SG11201609389QA
Other languages
English (en)
Inventor
Arthur P Bollon
Baoxi Qu
Original Assignee
Vitruvian Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vitruvian Biomedical Inc filed Critical Vitruvian Biomedical Inc
Publication of SG11201609389QA publication Critical patent/SG11201609389QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0007Nervous system antigens; Prions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1716Amyloid plaque core protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/06Fusion polypeptide containing a localisation/targetting motif containing a lysosomal/endosomal localisation signal
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/555Interferons [IFN]
    • G01N2333/57IFN-gamma
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • General Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • General Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
SG11201609389QA 2014-05-16 2015-05-15 Diagnostic test and treatment/prevention of alzheimer's disease SG11201609389QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461994644P 2014-05-16 2014-05-16
PCT/US2015/031011 WO2015175898A1 (en) 2014-05-16 2015-05-15 Diagnostic test and treatment/prevention of alzheimer's disease

Publications (1)

Publication Number Publication Date
SG11201609389QA true SG11201609389QA (en) 2016-12-29

Family

ID=54480752

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201609389QA SG11201609389QA (en) 2014-05-16 2015-05-15 Diagnostic test and treatment/prevention of alzheimer's disease

Country Status (12)

Country Link
US (1) US20160206714A1 (de)
EP (1) EP3142708A4 (de)
JP (1) JP2017521092A (de)
KR (1) KR20170040782A (de)
CN (1) CN106573075A (de)
AU (1) AU2015258996A1 (de)
BR (1) BR112016026694A2 (de)
CA (1) CA2978409A1 (de)
IL (1) IL248935A0 (de)
MX (1) MX2016014779A (de)
SG (1) SG11201609389QA (de)
WO (1) WO2015175898A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101989383B1 (ko) * 2017-04-04 2019-06-14 조선대학교산학협력단 알츠하이머성 치매의 조기진단을 위한 펩타이드 프로브
WO2020045962A1 (ko) * 2018-08-27 2020-03-05 광주과학기술원 알츠하이머성 치매 진단용 펩타이드 바이오마커
CN116705141B (zh) * 2022-12-15 2024-01-09 西北大学 一种基于cnn-lstm神经网络从核桃酶解产物中筛选阿尔兹海默症预防肽的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100450551C (zh) * 2002-11-29 2009-01-14 中国医学科学院基础医学研究所 用于治疗和预防阿尔茨海默病的重组腺相关病毒基因疫苗及其用途
WO2008148490A1 (de) * 2007-06-04 2008-12-11 F. Hoffmann-La Roche Ag Hsp27 as biomarker for alzheimer's disease

Also Published As

Publication number Publication date
AU2015258996A1 (en) 2016-12-01
KR20170040782A (ko) 2017-04-13
WO2015175898A1 (en) 2015-11-19
IL248935A0 (en) 2017-01-31
EP3142708A4 (de) 2018-01-17
CN106573075A (zh) 2017-04-19
US20160206714A1 (en) 2016-07-21
EP3142708A1 (de) 2017-03-22
CA2978409A1 (en) 2015-11-19
MX2016014779A (es) 2017-04-13
BR112016026694A2 (pt) 2017-10-31
JP2017521092A (ja) 2017-08-03

Similar Documents

Publication Publication Date Title
HK1253769A1 (zh) 用於診斷和治療腎上腺腦白質營養不良的方法和組合物
IL246917A0 (en) Biomarker and early diagnosis methods for Alzheimer's disease
IL247085A0 (en) Methods for treating Alzheimer's disease
ZA201605341B (en) Methods of treating alzheimer's disease
EP3104776A4 (de) Diagnose und behandlung von atemwegserkrankungen
GB201504432D0 (en) Materials and methods for diagnosis and treatment of alzheimers disease
SG11201703704PA (en) Diagnosis and treatment of incipient diabetes
HK1251265A1 (zh) 感染性疾病的診斷與治療
IL248592A0 (en) Treatment of Crohn's disease using delayed-release 6-mercaptofurin
IL248935A0 (en) Diagnostic testing and treatment/prevention of Alzheimer's disease
EP3137097C0 (de) Behandlung und prävention von alzheimer
HK1246271A1 (zh) 用於合成羥基-三甘油酯的方法及其用於預防和治療疾病的用途
PL3137093T3 (pl) Leczenie i profilaktyka choroby Alzheimera (AD)
PL3137094T3 (pl) Leczenie i profilaktyka choroby alzheimera (ad)
GB201411616D0 (en) Diagnosis and treatment of neurodegenerative disorders
ZA201801945B (en) Compositions and methods for the treatment of parkinson's disease
HK1225969A1 (zh) 利用低劑量的拉喹莫德治療克隆氏病
FR3016881B1 (fr) Traitement des degenerescences et des lesions photo-induites de la retine
GB201614076D0 (en) Diagnosis and treatment of ocular disorders
GB201609512D0 (en) Diagnosis and treatment of infectious disease
GB201609529D0 (en) Diagnosis and treatment of infectious disease
GB201511453D0 (en) Treatment of alzheimer's disease
GB201621398D0 (en) Treatment of emt-associated disease
AU2016902338A0 (en) Agents and methods for the diagnosis and treatment of disease
GB201510882D0 (en) Diagnosis and treatment of infectious disease