SG11201609248WA - Nox inhibitor and nfκb inhibitor containing methoxyflavone - Google Patents
Nox inhibitor and nfκb inhibitor containing methoxyflavoneInfo
- Publication number
- SG11201609248WA SG11201609248WA SG11201609248WA SG11201609248WA SG11201609248WA SG 11201609248W A SG11201609248W A SG 11201609248WA SG 11201609248W A SG11201609248W A SG 11201609248WA SG 11201609248W A SG11201609248W A SG 11201609248WA SG 11201609248W A SG11201609248W A SG 11201609248WA
- Authority
- SG
- Singapore
- Prior art keywords
- inhibitor
- nox
- nfκb
- methoxyflavone
- containing methoxyflavone
- Prior art date
Links
- FAWLNURBQMTKEB-URDPEVQOSA-N 213546-53-3 Chemical compound N([C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N1[C@@H](CCC1)C(O)=O)C(C)C)C(C)C)C(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)N)C(C)C FAWLNURBQMTKEB-URDPEVQOSA-N 0.000 title 1
- ZAIANDVQAMEDFL-UHFFFAOYSA-N 3-methoxy-2-phenylchromen-4-one Chemical compound O1C2=CC=CC=C2C(=O)C(OC)=C1C1=CC=CC=C1 ZAIANDVQAMEDFL-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- YEHDMSUNJUONMW-UHFFFAOYSA-N methoxyflavone Natural products COC1=CC=CC=C1C1=CC(=O)C2=CC=CC=C2O1 YEHDMSUNJUONMW-UHFFFAOYSA-N 0.000 title 1
- 230000017128 negative regulation of NF-kappaB transcription factor activity Effects 0.000 title 1
Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014097875 | 2014-05-09 | ||
PCT/JP2015/063100 WO2015170683A1 (en) | 2014-05-09 | 2015-05-01 | Nox inhibitor and nfκb inhibitor containing methoxyflavone |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201609248WA true SG11201609248WA (en) | 2016-12-29 |
Family
ID=54392533
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201609248WA SG11201609248WA (en) | 2014-05-09 | 2015-05-01 | Nox inhibitor and nfκb inhibitor containing methoxyflavone |
SG10201808940WA SG10201808940WA (en) | 2014-05-09 | 2015-05-01 | Nox inhibitor and nfкb inhibitor containing methoxyflavone |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201808940WA SG10201808940WA (en) | 2014-05-09 | 2015-05-01 | Nox inhibitor and nfкb inhibitor containing methoxyflavone |
Country Status (9)
Country | Link |
---|---|
US (1) | US20170071902A1 (en) |
JP (3) | JP6666837B2 (en) |
KR (1) | KR20170002565A (en) |
CN (1) | CN106456597A (en) |
AU (1) | AU2015256997B2 (en) |
CA (1) | CA2948127A1 (en) |
SG (2) | SG11201609248WA (en) |
TW (1) | TWI700278B (en) |
WO (1) | WO2015170683A1 (en) |
Families Citing this family (17)
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JP2017145221A (en) * | 2016-02-18 | 2017-08-24 | 株式会社レーネ | Tau protein aggregation inhibitor |
JP6909559B2 (en) * | 2016-03-31 | 2021-07-28 | 株式会社アンチエイジングコミュニケーション | OPH activity enhancer |
JP6462755B2 (en) * | 2017-04-04 | 2019-01-30 | 丸善製薬株式会社 | Brain function improving agent and food and drink for improving brain function |
TWI646943B (en) * | 2017-12-08 | 2019-01-11 | 財團法人自行車暨健康科技工業研究發展中心 | Method for screening for muscular dysfunction through functional fitness |
KR102032739B1 (en) * | 2018-01-31 | 2019-10-16 | 한림대학교 산학협력단 | Pharmaceutical composition for preventing and treating diabetic complications containing the novel chrysin derivative |
CN110237066B (en) * | 2018-03-07 | 2022-03-29 | 上海市生物医药技术研究院 | Application of 3-methoxyflavone and derivatives thereof in preparation of medicines for treating or preventing nephropathy |
CN108904489A (en) * | 2018-06-19 | 2018-11-30 | 杭州勃锐思莫生物医药科技有限责任公司 | The purposes of the preventing respiratory diseases associated with inflammation of 3,4 ' flavonol of 5,7- methoxyl group |
JP7229513B2 (en) * | 2018-10-16 | 2023-02-28 | 丸善製薬株式会社 | Brain function improving agent and food and drink for improving brain function |
CN109288834A (en) * | 2018-11-28 | 2019-02-01 | 武汉科技大学 | 5- methoxy flavone reads over the application in drug in preparation nonsense mutation |
WO2020178267A1 (en) * | 2019-03-04 | 2020-09-10 | Universite D'aix-Marseille | Nox inhibitors for preventing epileptic seizures |
CN110357846B (en) * | 2019-07-11 | 2021-06-15 | 上海健康医学院 | Flavone monoterpene compound and preparation method and application thereof |
US20230021051A1 (en) * | 2019-12-26 | 2023-01-19 | Maruzen Pharmaceuticals Co., Ltd. | Composition Containing Black Ginger Extract and Composition for Oral Administration |
CN111374970B (en) * | 2020-03-17 | 2023-05-30 | 广西壮族自治区中医药研究院 | Composition with anti-colitis activity and application thereof |
CN111617076B (en) * | 2020-06-24 | 2021-09-28 | 江苏吴中医药集团有限公司 | Compound pharmaceutical composition containing arbidol hydrochloride and application thereof |
JP7081843B2 (en) * | 2020-10-26 | 2022-06-07 | 株式会社東洋新薬 | Autonomic nerve regulator |
WO2022137964A1 (en) * | 2020-12-23 | 2022-06-30 | 国立大学法人大阪大学 | Pharmaceutical composition for preventing or treating cartilage/bone/joint diseases, and method for screening drug for preventing or treating cartilage/bone/joint diseases |
WO2023144742A1 (en) | 2022-01-26 | 2023-08-03 | Universidade De Aveiro | Ionic-liquid-based formulations for the prevention or treatment of neurological diseases |
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JP2005505506A (en) * | 2001-06-12 | 2005-02-24 | イーラン ファーマスーティカルズ、インコーポレイテッド | Macrocycles useful for the treatment of Alzheimer's disease |
JP2007314468A (en) * | 2006-05-25 | 2007-12-06 | Meiji Milk Prod Co Ltd | Compound for controlling endoplasmic reticulum stress and pharmaceutical composition containing the compound as active component |
JP2009051790A (en) * | 2007-08-29 | 2009-03-12 | Maruzen Pharmaceut Co Ltd | Antioxidant, anti-aging agent, anti-inflammatory agent, hair restoration agent, anti-obesity agent, skin-lightening agent, cosmetic and food and drink for cosmetic use |
JP5756264B2 (en) * | 2010-05-06 | 2015-07-29 | 日本タブレット株式会社 | Xanthine oxidase inhibitor, xanthine oxidase and 5α-reductase inhibitor, and pharmaceutical composition containing the inhibitor |
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US9669003B2 (en) * | 2012-06-13 | 2017-06-06 | Yongri Jin | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs |
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2015
- 2015-05-01 CN CN201580024156.6A patent/CN106456597A/en active Pending
- 2015-05-01 US US15/308,868 patent/US20170071902A1/en not_active Abandoned
- 2015-05-01 WO PCT/JP2015/063100 patent/WO2015170683A1/en active Application Filing
- 2015-05-01 SG SG11201609248WA patent/SG11201609248WA/en unknown
- 2015-05-01 SG SG10201808940WA patent/SG10201808940WA/en unknown
- 2015-05-01 KR KR1020167034094A patent/KR20170002565A/en not_active Application Discontinuation
- 2015-05-01 JP JP2016517902A patent/JP6666837B2/en active Active
- 2015-05-01 CA CA2948127A patent/CA2948127A1/en not_active Abandoned
- 2015-05-01 AU AU2015256997A patent/AU2015256997B2/en not_active Ceased
- 2015-05-01 JP JP2015093939A patent/JP2015227329A/en active Pending
- 2015-05-06 TW TW104114409A patent/TWI700278B/en active
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2019
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CA2948127A1 (en) | 2015-11-12 |
KR20170002565A (en) | 2017-01-06 |
WO2015170683A1 (en) | 2015-11-12 |
JP7015822B2 (en) | 2022-02-15 |
AU2015256997B2 (en) | 2020-07-09 |
AU2015256997A1 (en) | 2016-11-24 |
SG10201808940WA (en) | 2018-11-29 |
JP6666837B2 (en) | 2020-03-18 |
JP2020063283A (en) | 2020-04-23 |
JP2015227329A (en) | 2015-12-17 |
CN106456597A (en) | 2017-02-22 |
TW201625574A (en) | 2016-07-16 |
JPWO2015170683A1 (en) | 2017-04-20 |
US20170071902A1 (en) | 2017-03-16 |
TWI700278B (en) | 2020-08-01 |
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