SG11201609008PA - A novel affinity matrix and devices for isolation and purification of rna and dna for point of care molecular devices - Google Patents

A novel affinity matrix and devices for isolation and purification of rna and dna for point of care molecular devices

Info

Publication number
SG11201609008PA
SG11201609008PA SG11201609008PA SG11201609008PA SG11201609008PA SG 11201609008P A SG11201609008P A SG 11201609008PA SG 11201609008P A SG11201609008P A SG 11201609008PA SG 11201609008P A SG11201609008P A SG 11201609008PA SG 11201609008P A SG11201609008P A SG 11201609008PA
Authority
SG
Singapore
Prior art keywords
devices
rna
dna
isolation
purification
Prior art date
Application number
SG11201609008PA
Inventor
Raveendran Pottathil
Original Assignee
Accudx Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Accudx Corp filed Critical Accudx Corp
Publication of SG11201609008PA publication Critical patent/SG11201609008PA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/101—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by chromatography, e.g. electrophoresis, ion-exchange, reverse phase
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/043—Hinged closures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/048—Function or devices integrated in the closure enabling gas exchange, e.g. vents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Clinical Laboratory Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SG11201609008PA 2014-04-29 2015-04-29 A novel affinity matrix and devices for isolation and purification of rna and dna for point of care molecular devices SG11201609008PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461985998P 2014-04-29 2014-04-29
PCT/US2015/028374 WO2015168342A1 (en) 2014-04-29 2015-04-29 A novel affinity matrix and devices for isolation and purification of rna and dna for point of care molecular devices

Publications (1)

Publication Number Publication Date
SG11201609008PA true SG11201609008PA (en) 2016-11-29

Family

ID=54359314

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201609008PA SG11201609008PA (en) 2014-04-29 2015-04-29 A novel affinity matrix and devices for isolation and purification of rna and dna for point of care molecular devices

Country Status (4)

Country Link
US (2) US10597651B2 (en)
EP (1) EP3137603A4 (en)
SG (1) SG11201609008PA (en)
WO (1) WO2015168342A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11360076B2 (en) 2012-03-30 2022-06-14 Weavr Health Corp. Methods and systems to collect a biological sample
US11358138B2 (en) 2013-07-19 2022-06-14 Boston Microfluidics Inc. Fluid sample collection device
SG11202003744PA (en) 2017-10-27 2020-05-28 Boston Microfluidics Inc Fluid sample collection device
US11484877B2 (en) 2018-05-29 2022-11-01 Weavr Health Corp. Blood metering device with desiccant and support for storage media and inlay with flange
US11772097B2 (en) 2018-10-19 2023-10-03 Renegadexbio, Pbc Simultaneous spot test and storage of blood samples
USD921219S1 (en) * 2018-10-19 2021-06-01 Weave Health Corp. Blood storage device
WO2020086397A1 (en) 2018-10-23 2020-04-30 Boston Microfluidics, Inc. Funnel with extension tube to augment blood collection device
WO2023091993A1 (en) * 2021-11-17 2023-05-25 Board Of Regents, The University Of Texas System Water-soluble salts of dna binding agents

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
GB9003253D0 (en) 1990-02-13 1990-04-11 Amersham Int Plc Precipitating polymers
GB9425138D0 (en) 1994-12-12 1995-02-08 Dynal As Isolation of nucleic acid
US5593835A (en) 1995-05-12 1997-01-14 President And Fellows Of Harvard College Methods and kits for RNA binding compounds
CA2330819A1 (en) * 1998-05-04 1999-11-11 Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. Electrical integrated nucleic acid isolation, purification and detection
US20020012982A1 (en) * 2000-07-13 2002-01-31 Invitrogen Corporation Methods and compositions for rapid protein and peptide extraction and isolation using a lysis matrix
US7598371B2 (en) * 2000-11-06 2009-10-06 University Of Houston Nucleic acid separation using immobilized metal affinity chromatography
AU2003260679A1 (en) 2002-07-12 2004-02-02 British Biocell International Limited Lateral flow assay device and method
EP1556507A2 (en) 2002-10-09 2005-07-27 Hôpitaux Universitaires de Genève Analytical chip for the detection of 16s-rrna from clinically relevant bacteria and analytical method based thereon
US7897378B2 (en) 2004-03-18 2011-03-01 Roche Molecular Systems, Inc. Method and device for purifying nucleic acids
US7439343B2 (en) * 2005-09-01 2008-10-21 Rensselaer Polytechnic Institute Aminoglycoside-polyamine displacers and methods of use in displacement chromatography
US20080153078A1 (en) 2006-06-15 2008-06-26 Braman Jeffrey C System for isolating biomolecules from a sample
EP2279403B1 (en) 2008-05-05 2016-03-16 Los Alamos National Security, LLC Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control
CN102132156B (en) * 2008-08-01 2014-11-26 生物风险公司 Devices and methods for the purification, isolation, desalting or buffer/solvent exchange of substances
DK2588609T3 (en) 2010-06-29 2018-03-19 Exscale Biospecimen Solutions Ab METHOD AND KIT FOR SEQUENTIAL ISOLATION OF NUCLEOTIDE SPECIES FROM A SAMPLE

Also Published As

Publication number Publication date
US20200199569A1 (en) 2020-06-25
US11441145B2 (en) 2022-09-13
WO2015168342A1 (en) 2015-11-05
US10597651B2 (en) 2020-03-24
EP3137603A4 (en) 2017-10-11
EP3137603A1 (en) 2017-03-08
US20170044519A1 (en) 2017-02-16

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