SG11201608896QA - Stable compositions of neuroactive peptides - Google Patents

Stable compositions of neuroactive peptides

Info

Publication number
SG11201608896QA
SG11201608896QA SG11201608896QA SG11201608896QA SG11201608896QA SG 11201608896Q A SG11201608896Q A SG 11201608896QA SG 11201608896Q A SG11201608896Q A SG 11201608896QA SG 11201608896Q A SG11201608896Q A SG 11201608896QA SG 11201608896Q A SG11201608896Q A SG 11201608896QA
Authority
SG
Singapore
Prior art keywords
stable compositions
neuroactive peptides
neuroactive
peptides
compositions
Prior art date
Application number
SG11201608896QA
Inventor
David Renwick Houck
Mohsen Arghavani
Original Assignee
Naurex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Naurex Inc filed Critical Naurex Inc
Publication of SG11201608896QA publication Critical patent/SG11201608896QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
SG11201608896QA 2014-04-25 2015-04-27 Stable compositions of neuroactive peptides SG11201608896QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461984216P 2014-04-25 2014-04-25
PCT/US2015/027745 WO2015164859A1 (en) 2014-04-25 2015-04-27 Stable compositions of neuroactive peptides

Publications (1)

Publication Number Publication Date
SG11201608896QA true SG11201608896QA (en) 2016-11-29

Family

ID=54333349

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201608896QA SG11201608896QA (en) 2014-04-25 2015-04-27 Stable compositions of neuroactive peptides
SG10201803880TA SG10201803880TA (en) 2014-04-25 2015-04-27 Stable compositions of neuroactive peptides

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201803880TA SG10201803880TA (en) 2014-04-25 2015-04-27 Stable compositions of neuroactive peptides

Country Status (14)

Country Link
US (2) US20170049844A1 (en)
EP (2) EP3134103B1 (en)
JP (1) JP6702883B2 (en)
KR (1) KR20160144499A (en)
CN (2) CN106535913B (en)
AU (2) AU2015249222A1 (en)
BR (1) BR112016024841A2 (en)
CA (1) CA2946413A1 (en)
CL (1) CL2016002704A1 (en)
IL (1) IL248433B (en)
RU (1) RU2716164C2 (en)
SG (2) SG11201608896QA (en)
UA (1) UA122204C2 (en)
WO (1) WO2015164859A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111670041A (en) 2017-12-05 2020-09-15 诺雷克斯股份有限公司 Combination of NMDA receptor modulators (lapatin) for use in combination therapy (sleep disorders or central nervous system disorders)
WO2020146878A1 (en) * 2019-01-11 2020-07-16 Naurex Inc. Salt and crystalline forms of rapastinel

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4086196A (en) 1975-03-28 1978-04-25 Armour Pharmaceutical Company Parathyroid hormone
NZ212207A (en) * 1984-05-31 1991-07-26 Genentech Inc Recombinant lymphotoxin
US5763393A (en) 1996-05-17 1998-06-09 Neurotherapeutics L.P. Neuroactive peptides
HN1998000106A (en) * 1997-08-01 1999-01-08 Pfizer Prod Inc PARENTERAL COMPOSITIONS OF ALATROFLAXACINO
JP2008519007A (en) * 2004-11-04 2008-06-05 ノボ ノルディスク アクティーゼルスカブ Peptides for use in the treatment of obesity
KR20080027253A (en) * 2005-06-16 2008-03-26 미리어드 제네틱스, 인크. Pharmaceutical compositions and use thereof
AU2007258325B2 (en) * 2006-06-12 2013-02-21 Merck Sharp & Dohme Corp. Pharmaceutical formulations and compositions of a selective antagonist of either CXCR2 or both CXCR1 and CXCR2 and methods of using the same for treating inflammatory disorders
WO2011003064A2 (en) * 2009-07-02 2011-01-06 Naurex, Inc. Methods of treating neuropathic pain
MX2012009388A (en) * 2010-02-11 2012-10-01 Univ Northwestern Secondary structure stabilized nmda receptor modulators and uses thereof.
US9321848B2 (en) * 2011-06-28 2016-04-26 Leukocare Ag Method for preventing the unfolding of a (poly)peptide and/or inducing the (re-)folding of a (poly)peptide
EP2572736A1 (en) * 2011-09-23 2013-03-27 Spago Imaging AB Nanostructures comprising manganese
WO2013188465A2 (en) * 2012-06-13 2013-12-19 Arizona Board Of Regents, For And On Behalf Of, Arizona State University Pharmaceutical compositions and methods for treating drug addiction and preventing a drug relapse
US20140050789A1 (en) * 2012-08-13 2014-02-20 The Regents Of The University Of California Mitigation of epileptic seizures by combination therapy using benzodiazepines and neurosteroids

Also Published As

Publication number Publication date
EP3134103A4 (en) 2017-12-27
CN112716890A (en) 2021-04-30
WO2015164859A1 (en) 2015-10-29
US20200254050A1 (en) 2020-08-13
JP6702883B2 (en) 2020-06-03
AU2015249222A1 (en) 2016-11-17
CN106535913B (en) 2021-01-26
CA2946413A1 (en) 2015-10-29
KR20160144499A (en) 2016-12-16
CN106535913A (en) 2017-03-22
AU2020277278A1 (en) 2021-01-07
RU2016144342A (en) 2018-05-28
RU2716164C2 (en) 2020-03-06
EP3134103B1 (en) 2020-01-15
JP2017514817A (en) 2017-06-08
EP3689362A1 (en) 2020-08-05
BR112016024841A2 (en) 2017-10-24
EP3134103A1 (en) 2017-03-01
IL248433B (en) 2020-03-31
US20170049844A1 (en) 2017-02-23
IL248433A0 (en) 2016-12-29
RU2016144342A3 (en) 2018-11-13
UA122204C2 (en) 2020-10-12
SG10201803880TA (en) 2018-07-30
CL2016002704A1 (en) 2017-06-30

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