SG11201608659TA - Vnar recombinant monoclonal antibodies that neutralize vascular endophelial growth factor vegf - Google Patents
Vnar recombinant monoclonal antibodies that neutralize vascular endophelial growth factor vegfInfo
- Publication number
- SG11201608659TA SG11201608659TA SG11201608659TA SG11201608659TA SG11201608659TA SG 11201608659T A SG11201608659T A SG 11201608659TA SG 11201608659T A SG11201608659T A SG 11201608659TA SG 11201608659T A SG11201608659T A SG 11201608659TA SG 11201608659T A SG11201608659T A SG 11201608659TA
- Authority
- SG
- Singapore
- Prior art keywords
- endophelial
- vnar
- growth factor
- monoclonal antibodies
- recombinant monoclonal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/ES2014/070332 WO2015158937A1 (en) | 2014-04-17 | 2014-04-17 | Vnar recombinant monoclonal antibodies that neutralize vascular endophelial growth factor vegf |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201608659TA true SG11201608659TA (en) | 2016-12-29 |
Family
ID=50877332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201608659TA SG11201608659TA (en) | 2014-04-17 | 2014-04-17 | Vnar recombinant monoclonal antibodies that neutralize vascular endophelial growth factor vegf |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10370442B2 (en) |
| EP (1) | EP3133085A1 (en) |
| JP (1) | JP6426198B2 (en) |
| KR (1) | KR20160145166A (en) |
| CN (1) | CN106459193A (en) |
| AR (1) | AR101647A1 (en) |
| AU (1) | AU2014391247A1 (en) |
| BR (1) | BR112016023980A2 (en) |
| CA (1) | CA2946086A1 (en) |
| IL (1) | IL248320A0 (en) |
| MX (1) | MX2016013613A (en) |
| RU (1) | RU2016145136A (en) |
| SG (1) | SG11201608659TA (en) |
| TW (1) | TWI547501B (en) |
| UY (1) | UY36082A (en) |
| WO (1) | WO2015158937A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3518913A4 (en) * | 2016-09-29 | 2020-05-27 | NatureWise Biotech & Medicals Corporation | Methods for treating ocular diseases |
| US11155612B2 (en) | 2017-04-21 | 2021-10-26 | Centro De Investigación Científica Y De Educación Superior De Ensenada, Baja California | vNAR antibody which binds VEGF for use in dogs or cats |
| CN109593117B (en) * | 2019-01-11 | 2021-12-31 | 广州领晟医疗科技有限公司 | Polypeptide CKA18N for inhibiting angiogenesis and application thereof |
| CN109776656B (en) * | 2019-01-11 | 2022-03-11 | 广州领晟医疗科技有限公司 | Polypeptide TIN7N for inhibiting angiogenesis and application thereof |
| EP4141028A1 (en) | 2021-08-31 | 2023-03-01 | Johann-Wolfgang-Goethe-Universität Frankfurt am Main | Personalized vnar-based chimeric antigen receptors (vnar-car) for the treatment of clonal b-and t cell malignancies, and methods for producing vnar-cars |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2567655C (en) * | 2004-06-02 | 2015-06-30 | Diatech Pty Ltd | Binding moieties based on shark ignar domains |
| US20100092470A1 (en) * | 2008-09-22 | 2010-04-15 | Icb International, Inc. | Antibodies, analogs and uses thereof |
| US20100136584A1 (en) * | 2008-09-22 | 2010-06-03 | Icb International, Inc. | Methods for using antibodies and analogs thereof |
| EP2344545A4 (en) * | 2008-10-06 | 2012-10-03 | Commw Scient Ind Res Org | Amyloid-beta peptide crystal structure |
| EP2435478A1 (en) * | 2009-05-28 | 2012-04-04 | Glaxo Group Limited | Antigen-binding proteins |
| WO2011056056A2 (en) | 2009-11-04 | 2011-05-12 | Laboratorios Silanes, S.A. De C.V. | Anti-cytokine vhnar domains |
-
2014
- 2014-04-17 CA CA2946086A patent/CA2946086A1/en not_active Abandoned
- 2014-04-17 CN CN201480078046.3A patent/CN106459193A/en active Pending
- 2014-04-17 AU AU2014391247A patent/AU2014391247A1/en not_active Abandoned
- 2014-04-17 EP EP14727573.9A patent/EP3133085A1/en not_active Withdrawn
- 2014-04-17 MX MX2016013613A patent/MX2016013613A/en unknown
- 2014-04-17 SG SG11201608659TA patent/SG11201608659TA/en unknown
- 2014-04-17 BR BR112016023980A patent/BR112016023980A2/en not_active IP Right Cessation
- 2014-04-17 JP JP2016562017A patent/JP6426198B2/en not_active Expired - Fee Related
- 2014-04-17 RU RU2016145136A patent/RU2016145136A/en not_active Application Discontinuation
- 2014-04-17 US US15/304,516 patent/US10370442B2/en active Active
- 2014-04-17 WO PCT/ES2014/070332 patent/WO2015158937A1/en active Application Filing
- 2014-04-17 KR KR1020167032052A patent/KR20160145166A/en not_active Application Discontinuation
-
2015
- 2015-04-07 AR ARP150101038A patent/AR101647A1/en unknown
- 2015-04-10 TW TW104111642A patent/TWI547501B/en not_active IP Right Cessation
- 2015-04-15 UY UY0001036082A patent/UY36082A/en not_active Application Discontinuation
-
2016
- 2016-10-13 IL IL248320A patent/IL248320A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2016145136A (en) | 2018-05-17 |
| BR112016023980A2 (en) | 2017-10-17 |
| UY36082A (en) | 2015-11-30 |
| IL248320A0 (en) | 2016-11-30 |
| TWI547501B (en) | 2016-09-01 |
| WO2015158937A1 (en) | 2015-10-22 |
| CN106459193A (en) | 2017-02-22 |
| AU2014391247A1 (en) | 2016-12-08 |
| TW201546090A (en) | 2015-12-16 |
| US20170137504A1 (en) | 2017-05-18 |
| JP2017513475A (en) | 2017-06-01 |
| CA2946086A1 (en) | 2015-10-22 |
| KR20160145166A (en) | 2016-12-19 |
| JP6426198B2 (en) | 2018-11-21 |
| US10370442B2 (en) | 2019-08-06 |
| MX2016013613A (en) | 2017-02-28 |
| RU2016145136A3 (en) | 2018-08-08 |
| EP3133085A1 (en) | 2017-02-22 |
| AR101647A1 (en) | 2017-01-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA202003742B (en) | Anti-lag3 antibodies and antigen-binding fragments | |
| ZA201803874B (en) | Humanized anti-cd73 antibodies | |
| HK1251483A1 (en) | Humanized affinity matured anti-fcrn antibodies | |
| IL251537A0 (en) | Humanized anti-ox40 antibodies and uses thereof | |
| HK1258375A1 (en) | Humanized anti-cll-1 antibodies | |
| IL253909A0 (en) | Humanized anti-muc1* antibodies | |
| SG10201603721TA (en) | Anti-CTLA-4 Antibodies | |
| IL247277A0 (en) | Ebola monoclonal antibodies | |
| IL256579A (en) | Humanized antibodies | |
| IL248402A0 (en) | Humanized antibodies against ceacam1 | |
| PT3101131T (en) | Anti-transthyretin humanized antibody | |
| IL257359B (en) | Humanized anti-ccr7 receptor antibodies | |
| GB201506409D0 (en) | Humanized anti-axl antibodies and their conjugates | |
| IL262776A (en) | Humanized anti-il-1r3 antibodies | |
| EP3103811A4 (en) | Anti-tissue factor monoclonal antibody | |
| IL248320A0 (en) | Recombinant monoclonal antibodies vnar neutralizing the vascular endothelial growth factor vegf | |
| HUE046308T2 (en) | Humanized kir3dl2 antibodies | |
| PL3371216T3 (en) | Humanized anti-bag3 antibodies | |
| IL262536A (en) | Humanized affinity matured anti-fcrn antibodies | |
| GB201511196D0 (en) | Monoclonal antibodies |