SG11201607896YA - 2-AMINO-6-METHYL-4,4a,5,6-TETRAHYDROPYRANO[3,4-d][1,3]THIAZIN-8a(8H)-YL-1,3-THIAZOL-4-YL AMIDES - Google Patents
2-AMINO-6-METHYL-4,4a,5,6-TETRAHYDROPYRANO[3,4-d][1,3]THIAZIN-8a(8H)-YL-1,3-THIAZOL-4-YL AMIDESInfo
- Publication number
- SG11201607896YA SG11201607896YA SG11201607896YA SG11201607896YA SG11201607896YA SG 11201607896Y A SG11201607896Y A SG 11201607896YA SG 11201607896Y A SG11201607896Y A SG 11201607896YA SG 11201607896Y A SG11201607896Y A SG 11201607896YA SG 11201607896Y A SG11201607896Y A SG 11201607896YA
- Authority
- SG
- Singapore
- Prior art keywords
- tetrahydropyrano
- thiazin
- thiazol
- amides
- amino
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461977774P | 2014-04-10 | 2014-04-10 | |
| US201562119862P | 2015-02-24 | 2015-02-24 | |
| PCT/IB2015/052279 WO2015155626A1 (en) | 2014-04-10 | 2015-03-27 | 2-AMINO-6-METHYL-4,4a,5,6-TETRAHYDROPYRANO[3,4-d][1,3]THIAZIN-8a(8H)-YL-1,3-THIAZOL-4-YL AMIDES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201607896YA true SG11201607896YA (en) | 2016-10-28 |
Family
ID=53005609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201607896YA SG11201607896YA (en) | 2014-04-10 | 2015-03-27 | 2-AMINO-6-METHYL-4,4a,5,6-TETRAHYDROPYRANO[3,4-d][1,3]THIAZIN-8a(8H)-YL-1,3-THIAZOL-4-YL AMIDES |
Country Status (26)
| Country | Link |
|---|---|
| US (5) | US9315520B2 (en) |
| EP (1) | EP3129388A1 (en) |
| JP (1) | JP6111002B1 (en) |
| KR (2) | KR20180078347A (en) |
| CN (1) | CN106459088A (en) |
| AP (1) | AP2016009493A0 (en) |
| AU (1) | AU2015245260A1 (en) |
| CA (1) | CA2944971C (en) |
| CL (1) | CL2016002510A1 (en) |
| CR (1) | CR20160455A (en) |
| CU (1) | CU20160151A7 (en) |
| DO (1) | DOP2016000276A (en) |
| EA (1) | EA030085B1 (en) |
| EC (1) | ECSP16079730A (en) |
| IL (1) | IL248277A0 (en) |
| MA (1) | MA39866A (en) |
| MD (1) | MD20160105A2 (en) |
| MX (1) | MX2016013329A (en) |
| PE (1) | PE20170327A1 (en) |
| PH (1) | PH12016501977A1 (en) |
| SG (1) | SG11201607896YA (en) |
| SV (1) | SV2016005294A (en) |
| TW (1) | TWI551605B (en) |
| UY (1) | UY36073A (en) |
| WO (1) | WO2015155626A1 (en) |
| ZA (1) | ZA201606517B (en) |
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| EP2935282A1 (en) | 2012-12-19 | 2015-10-28 | Pfizer Inc. | CARBOCYCLIC- AND HETEROCYCLIC-SUBSTITUTED HEXAHYDROPYRANO[3,4-d][1,3]THIAZIN-2-AMINE COMPOUNDS |
| MX2016013329A (en) | 2014-04-10 | 2017-01-26 | Pfizer | 2-AMINO-6-METHYL-4,4a,5,6-TETRAHYDROPYRANO[3,4-d][1,3]THIAZIN-8a (8H)-YL-1,3-THIAZOL-4-YL AMIDES. |
| EP3353182A1 (en) * | 2015-09-24 | 2018-08-01 | Pfizer Inc | Tetrahydropyrano[3,4-d][1,3]oxazin derivatives and their use as bace inhibitors |
| JP2018531923A (en) | 2015-09-24 | 2018-11-01 | ファイザー・インク | N- [2- (2-Amino-6,6-disubstituted-4,4a, 5,6-tetrahydropyrano [3,4-d] [1,3] thiazin-8a (8H) -yl)- 1,3-thiazol-4-yl] amide |
| WO2017051294A1 (en) | 2015-09-24 | 2017-03-30 | Pfizer Inc. | N-[2-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2h-1,2,4-thiadiazin-5-yl)-1,3-thiazol-4-yl] amides useful as bace inhibitors |
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| WO2024068950A1 (en) | 2022-09-30 | 2024-04-04 | Syngenta Crop Protection Ag | Microbiocidal pyrazole derivatives |
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| WO2017051294A1 (en) | 2015-09-24 | 2017-03-30 | Pfizer Inc. | N-[2-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2h-1,2,4-thiadiazin-5-yl)-1,3-thiazol-4-yl] amides useful as bace inhibitors |
| JP2018531923A (en) | 2015-09-24 | 2018-11-01 | ファイザー・インク | N- [2- (2-Amino-6,6-disubstituted-4,4a, 5,6-tetrahydropyrano [3,4-d] [1,3] thiazin-8a (8H) -yl)- 1,3-thiazol-4-yl] amide |
| EP3353182A1 (en) | 2015-09-24 | 2018-08-01 | Pfizer Inc | Tetrahydropyrano[3,4-d][1,3]oxazin derivatives and their use as bace inhibitors |
-
2015
- 2015-03-27 MX MX2016013329A patent/MX2016013329A/en unknown
- 2015-03-27 AU AU2015245260A patent/AU2015245260A1/en not_active Abandoned
- 2015-03-27 CA CA2944971A patent/CA2944971C/en not_active Expired - Fee Related
- 2015-03-27 MD MDA20160105A patent/MD20160105A2/en not_active Application Discontinuation
- 2015-03-27 AP AP2016009493A patent/AP2016009493A0/en unknown
- 2015-03-27 CN CN201580024651.7A patent/CN106459088A/en active Pending
- 2015-03-27 KR KR1020187018817A patent/KR20180078347A/en active Application Filing
- 2015-03-27 SG SG11201607896YA patent/SG11201607896YA/en unknown
- 2015-03-27 KR KR1020167031098A patent/KR101875811B1/en active IP Right Grant
- 2015-03-27 CR CR20160455A patent/CR20160455A/en unknown
- 2015-03-27 JP JP2016560960A patent/JP6111002B1/en not_active Expired - Fee Related
- 2015-03-27 EA EA201600636A patent/EA030085B1/en not_active IP Right Cessation
- 2015-03-27 PE PE2016001933A patent/PE20170327A1/en not_active Application Discontinuation
- 2015-03-27 WO PCT/IB2015/052279 patent/WO2015155626A1/en active Application Filing
- 2015-03-27 EP EP15718621.4A patent/EP3129388A1/en not_active Withdrawn
- 2015-03-27 MA MA039866A patent/MA39866A/en unknown
- 2015-04-09 US US14/682,151 patent/US9315520B2/en not_active Expired - Fee Related
- 2015-04-09 TW TW104111483A patent/TWI551605B/en not_active IP Right Cessation
- 2015-04-10 UY UY0001036073A patent/UY36073A/en not_active Application Discontinuation
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2016
- 2016-02-09 US US15/019,342 patent/US9428523B2/en not_active Expired - Fee Related
- 2016-07-20 US US15/215,193 patent/US9605007B2/en not_active Expired - Fee Related
- 2016-09-21 ZA ZA2016/06517A patent/ZA201606517B/en unknown
- 2016-09-30 SV SV2016005294A patent/SV2016005294A/en unknown
- 2016-10-03 CL CL2016002510A patent/CL2016002510A1/en unknown
- 2016-10-04 PH PH12016501977A patent/PH12016501977A1/en unknown
- 2016-10-07 EC ECIEPI201679730A patent/ECSP16079730A/en unknown
- 2016-10-07 CU CUP2016000151A patent/CU20160151A7/en unknown
- 2016-10-09 IL IL248277A patent/IL248277A0/en unknown
- 2016-10-10 DO DO2016000276A patent/DOP2016000276A/en unknown
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2017
- 2017-02-08 US US15/427,350 patent/US9744173B2/en not_active Expired - Fee Related
- 2017-06-21 US US15/629,215 patent/US10028962B2/en not_active Expired - Fee Related
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