SG11201607287XA - Recombinant isfahan viral vectors - Google Patents

Recombinant isfahan viral vectors

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Publication number
SG11201607287XA
SG11201607287XA SG11201607287XA SG11201607287XA SG11201607287XA SG 11201607287X A SG11201607287X A SG 11201607287XA SG 11201607287X A SG11201607287X A SG 11201607287XA SG 11201607287X A SG11201607287X A SG 11201607287XA SG 11201607287X A SG11201607287X A SG 11201607287XA
Authority
SG
Singapore
Prior art keywords
viral vectors
isfahan
recombinant
recombinant isfahan
viral
Prior art date
Application number
SG11201607287XA
Inventor
Farooq Nasar
Demetrius Matassov
Rodion V Gorchakov
Stefan Hamm
Rebecca Nowak
Robert L Seymour
John H Eldridge
Robert B Tesh
David K Clarke
Theresa E Latham
Scott Weaver
Original Assignee
Univ Texas
Profectus Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Profectus Biosciences Inc filed Critical Univ Texas
Publication of SG11201607287XA publication Critical patent/SG11201607287XA/en

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    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02Recovery or purification
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/21Retroviridae, e.g. equine infectious anemia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
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    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04Inactivation or attenuation; Producing viral sub-units
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
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    • C12N2740/00Reverse transcribing RNA viruses
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    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
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    • C12N2740/16071Demonstrated in vivo effect
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    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
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    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20221Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20241Use of virus, viral particle or viral elements as a vector
    • C12N2760/20243Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20261Methods of inactivation or attenuation
    • C12N2760/20262Methods of inactivation or attenuation by genetic engineering
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20271Demonstrated in vivo effect
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    • C12N2770/00011Details
    • C12N2770/36011Togaviridae
    • C12N2770/36111Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/36011Togaviridae
    • C12N2770/36111Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36171Demonstrated in vivo effect
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
SG11201607287XA 2014-03-01 2015-02-27 Recombinant isfahan viral vectors SG11201607287XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461946734P 2014-03-01 2014-03-01
PCT/US2015/018156 WO2015134332A2 (en) 2014-03-01 2015-02-27 Recombinant isfahan viral vectors

Publications (1)

Publication Number Publication Date
SG11201607287XA true SG11201607287XA (en) 2016-09-29

Family

ID=54055975

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201607287XA SG11201607287XA (en) 2014-03-01 2015-02-27 Recombinant isfahan viral vectors

Country Status (14)

Country Link
US (1) US9932564B2 (en)
EP (1) EP3113795B1 (en)
JP (3) JP2017508465A (en)
KR (1) KR102416194B1 (en)
CN (1) CN106794240A (en)
AU (1) AU2015225553B2 (en)
CA (1) CA2941261A1 (en)
DK (1) DK3113795T3 (en)
ES (1) ES2749381T3 (en)
IL (2) IL247545B (en)
MX (1) MX369776B (en)
SG (1) SG11201607287XA (en)
WO (1) WO2015134332A2 (en)
ZA (1) ZA201606036B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11364292B2 (en) 2015-07-21 2022-06-21 Modernatx, Inc. CHIKV RNA vaccines
WO2017070624A1 (en) 2015-10-22 2017-04-27 Modernatx, Inc. Tropical disease vaccines
US11786607B2 (en) 2017-06-15 2023-10-17 Modernatx, Inc. RNA formulations
US11744801B2 (en) 2017-08-31 2023-09-05 Modernatx, Inc. Methods of making lipid nanoparticles
WO2019055807A1 (en) 2017-09-14 2019-03-21 Modernatx, Inc. Zika virus rna vaccines
CA3075990A1 (en) * 2017-09-15 2019-03-21 Ohio State Innovation Foundation Vaccines and methods of making and using vaccines for prevention of respiratory syncytial virus (rsv) infections
US20210290705A1 (en) * 2018-07-17 2021-09-23 Yale University Methods for treatment of cancer using chikungunya-vsv chimeric virus

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7153510B1 (en) * 1995-05-04 2006-12-26 Yale University Recombinant vesiculoviruses and their uses
WO2004093906A1 (en) 2003-03-26 2004-11-04 Wyeth Immunogenic composition and methods
CA2799469C (en) * 2004-04-09 2016-06-07 Wyeth Synergistic attenuation of vesicular stomatitis virus, vectors thereof and immunogenic compositions thereof
KR101255016B1 (en) 2004-04-09 2013-04-17 와이어쓰 엘엘씨 Synergistic attenuation of vesicular stomatitis virus, vectors thereof and immunogenic compositions thereof
US8481023B2 (en) * 2006-09-15 2013-07-09 Ottawa Hospital Research Institute Oncolytic rhabdovirus
MX342449B (en) * 2007-08-03 2016-09-29 Pasteur Institut Lentiviral gene transfer vectors and their medicinal applications.
CA2717499A1 (en) * 2008-03-14 2009-09-17 Sanofi Pasteur Biologics Co. Replication-defective flavivirus vaccines and vaccine vectors
US9707285B2 (en) * 2009-03-16 2017-07-18 Turnstone Limited Partnership Vaccination methods
ES2533345T3 (en) * 2009-06-08 2015-04-09 The University Of Western Ontario Different serotypes of vesicular stomatitis virus as expression vectors for immunization regimens
ES2788198T3 (en) 2010-05-14 2020-10-20 Univ Oregon Health & Science Recombinant hCMV and hCMV vectors encoding a heterologous antigen isolated from hepatitis B virus and uses thereof
US20130095556A1 (en) * 2011-09-21 2013-04-18 International Aids Vaccine Initiative Novel vesicular stomatitis virus and virus rescue system

Also Published As

Publication number Publication date
KR102416194B1 (en) 2022-07-04
EP3113795B1 (en) 2019-07-10
EP3113795A4 (en) 2017-07-26
WO2015134332A3 (en) 2016-01-28
EP3113795A2 (en) 2017-01-11
JP2020078318A (en) 2020-05-28
ZA201606036B (en) 2020-02-26
IL247545B (en) 2022-03-01
CN106794240A (en) 2017-05-31
DK3113795T3 (en) 2019-10-21
CA2941261A1 (en) 2015-09-11
US9932564B2 (en) 2018-04-03
WO2015134332A2 (en) 2015-09-11
IL290258A (en) 2022-04-01
IL247545A0 (en) 2016-11-30
AU2015225553A1 (en) 2016-09-15
AU2015225553B2 (en) 2020-02-27
MX369776B (en) 2019-11-21
KR20160135740A (en) 2016-11-28
JP2017508465A (en) 2017-03-30
JP2022126723A (en) 2022-08-30
US20170067027A1 (en) 2017-03-09
JP7454393B2 (en) 2024-03-22
ES2749381T3 (en) 2020-03-20
MX2016011300A (en) 2017-05-08

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