SG11201607038TA - Viral resistant cells and uses thereof - Google Patents

Viral resistant cells and uses thereof

Info

Publication number
SG11201607038TA
SG11201607038TA SG11201607038TA SG11201607038TA SG11201607038TA SG 11201607038T A SG11201607038T A SG 11201607038TA SG 11201607038T A SG11201607038T A SG 11201607038TA SG 11201607038T A SG11201607038T A SG 11201607038TA SG 11201607038T A SG11201607038T A SG 11201607038TA
Authority
SG
Singapore
Prior art keywords
resistant cells
viral resistant
viral
cells
resistant
Prior art date
Application number
SG11201607038TA
Inventor
Nan Lin
Joaquina Mascarenhas
Audrey Chang
David Onions
Henry George
Kevin Kayser
Original Assignee
Sigma Aldrich Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Aldrich Co Llc filed Critical Sigma Aldrich Co Llc
Publication of SG11201607038TA publication Critical patent/SG11201607038TA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C12Y204/01101—Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (2.4.1.101)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C12Y204/01144—Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (2.4.1.144)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C12Y204/01155—Alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase (2.4.1.155)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y603/00—Ligases forming carbon-nitrogen bonds (6.3)
    • C12Y603/01—Acid-ammonia (or amine)ligases (amide synthases)(6.3.1)
    • C12Y603/01002—Glutamate-ammonia ligase (6.3.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases (EC 2.)
    • C12N2501/724—Glycosyltransferases (EC 2.4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14311—Parvovirus, e.g. minute virus of mice

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11201607038TA 2014-03-04 2015-03-03 Viral resistant cells and uses thereof SG11201607038TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461947860P 2014-03-04 2014-03-04
PCT/US2015/018474 WO2015134488A1 (en) 2014-03-04 2015-03-03 Viral resistant cells and uses thereof

Publications (1)

Publication Number Publication Date
SG11201607038TA true SG11201607038TA (en) 2016-09-29

Family

ID=54055790

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201807208RA SG10201807208RA (en) 2014-03-04 2015-03-03 Viral resistant cells and uses thereof
SG11201607038TA SG11201607038TA (en) 2014-03-04 2015-03-03 Viral resistant cells and uses thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201807208RA SG10201807208RA (en) 2014-03-04 2015-03-03 Viral resistant cells and uses thereof

Country Status (10)

Country Link
US (1) US10377990B2 (en)
EP (2) EP3736325A1 (en)
JP (2) JP6751347B2 (en)
KR (2) KR20220013460A (en)
CN (2) CN111849921A (en)
BR (1) BR112016020287B1 (en)
ES (1) ES2797050T3 (en)
IL (2) IL247460B (en)
SG (2) SG10201807208RA (en)
WO (1) WO2015134488A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201807208RA (en) 2014-03-04 2018-09-27 Sigma Aldrich Co Llc Viral resistant cells and uses thereof
US10053671B2 (en) 2014-06-20 2018-08-21 Wisconsin Alumni Research Foundation (Warf) Mutations that confer genetic stability to additional genes in influenza viruses
CA2967595A1 (en) 2014-11-12 2016-05-19 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
US10889845B2 (en) 2015-07-16 2021-01-12 University Of Copenhagen Production of N-glycoproteins for enzyme assisted glycomodification
MX2018005061A (en) 2015-11-12 2019-02-28 Siamab Therapeutics Inc Glycan-interacting compounds and methods of use.
EP3205719A1 (en) * 2016-02-15 2017-08-16 CEVEC Pharmaceuticals GmbH Cell lines for producing recombinant glycoproteins with di-antennary n-glycans, methods using the same, and recombinant glycoproteins
WO2017194699A1 (en) * 2016-05-13 2017-11-16 University Of Copenhagen A cell-based array platform
JP7150731B2 (en) 2016-09-22 2022-10-11 シグマ－アルドリッチ・カンパニー・リミテッド・ライアビリティ・カンパニー Switching from single-primer to dual-primer amplicons
US11401330B2 (en) 2016-11-17 2022-08-02 Seagen Inc. Glycan-interacting compounds and methods of use
WO2018140478A1 (en) * 2017-01-24 2018-08-02 Sigma-Aldrich Co. Llc Viral resistant cells and culture systems
CN110913903B (en) 2017-03-03 2024-03-01 思进股份有限公司 Glycan interaction compounds and methods of use
EP3382014A1 (en) 2017-03-29 2018-10-03 CEVEC Pharmaceuticals GmbH Recombinant glycoproteins with reduced antennary fucosylation
US11709155B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US11709156B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved analytical analysis
CN107937349B (en) * 2017-11-27 2021-01-15 中国检验检疫科学研究院 Cell line for stably expressing African swine fever virus P54 protein and preparation and application thereof
EP3717640A1 (en) 2017-11-28 2020-10-07 Danmarks Tekniske Universitet Glycosylation of proteins
AU2019245243A1 (en) * 2018-03-29 2020-09-03 Genentech, Inc Modulating lactogenic activity in mammalian cells
CN108504693A (en) * 2018-04-04 2018-09-07 首都医科大学附属北京朝阳医院 The O-type that T synthase genes structure is knocked out using Crispr technologies glycosylates abnormal colon carcinoma cell line
EP3921413A1 (en) * 2019-02-08 2021-12-15 Wisconsin Alumni Research Foundation (WARF) Humanized cell line
CN110029129A (en) * 2019-03-06 2019-07-19 华南农业大学 A kind of construction method of MDCK stable cell strain that expressing 1 gene of chicken ST3GAL
CN111735801B (en) * 2019-03-25 2021-09-28 南京大学 Fluorescence analysis method based on HCR and cation exchange reaction of hydrogel
US11807872B2 (en) 2019-08-27 2023-11-07 Wisconsin Alumni Research Foundation (Warf) Recombinant influenza viruses with stabilized HA for replication in eggs
US11918936B2 (en) 2020-01-17 2024-03-05 Waters Technologies Corporation Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding
CN116323939A (en) * 2020-07-17 2023-06-23 创观（苏州）生物科技有限公司 Virus-insensitive animal and construction method thereof
CN116440269B (en) * 2022-01-10 2024-02-09 华中农业大学 Application of SLC35A1 gene as target spot in prevention and treatment of porcine epidemic diarrhea

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5487994A (en) 1992-04-03 1996-01-30 The Johns Hopkins University Insertion and deletion mutants of FokI restriction endonuclease
US5356802A (en) 1992-04-03 1994-10-18 The Johns Hopkins University Functional domains in flavobacterium okeanokoites (FokI) restriction endonuclease
US5436150A (en) 1992-04-03 1995-07-25 The Johns Hopkins University Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease
US6242568B1 (en) 1994-01-18 2001-06-05 The Scripps Research Institute Zinc finger protein derivatives and methods therefor
US6140466A (en) 1994-01-18 2000-10-31 The Scripps Research Institute Zinc finger protein derivatives and methods therefor
GB9824544D0 (en) 1998-11-09 1999-01-06 Medical Res Council Screening system
JP4118327B2 (en) 1994-08-20 2008-07-16 ゲンダック・リミテッド Improvements in or related to binding proteins for DNA recognition
US5789538A (en) 1995-02-03 1998-08-04 Massachusetts Institute Of Technology Zinc finger proteins with high affinity new DNA binding specificities
US5925523A (en) 1996-08-23 1999-07-20 President & Fellows Of Harvard College Intraction trap assay, reagents and uses thereof
GB9703369D0 (en) 1997-02-18 1997-04-09 Lindqvist Bjorn H Process
GB2338237B (en) 1997-02-18 2001-02-28 Actinova Ltd In vitro peptide or protein expression library
GB9710809D0 (en) 1997-05-23 1997-07-23 Medical Res Council Nucleic acid binding proteins
US6410248B1 (en) 1998-01-30 2002-06-25 Massachusetts Institute Of Technology General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites
ATE466952T1 (en) 1998-03-02 2010-05-15 Massachusetts Inst Technology POLY ZINC FINGER PROTEINS WITH IMPROVED LINKERS
US6453242B1 (en) 1999-01-12 2002-09-17 Sangamo Biosciences, Inc. Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites
US6534261B1 (en) 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US6794136B1 (en) 2000-11-20 2004-09-21 Sangamo Biosciences, Inc. Iterative optimization in the design of binding proteins
AU2001263155A1 (en) 2000-05-16 2001-11-26 Massachusetts Institute Of Technology Methods and compositions for interaction trap assays
US7888121B2 (en) 2003-08-08 2011-02-15 Sangamo Biosciences, Inc. Methods and compositions for targeted cleavage and recombination
EP2311530A2 (en) * 2004-10-27 2011-04-20 Vanderbilt University Mammalian genes involved in infection
US8658622B2 (en) * 2005-01-14 2014-02-25 Regents Of The University Of California Methods and compositions for preventing and treating a disease related to glycan dysregulation
AU2006254862B2 (en) * 2005-06-08 2011-04-07 The Regents Of The University Of California Elimination of N-glycolylneuraminic acid from mammalian products for human use
EP1913149A4 (en) 2005-07-26 2009-08-05 Sangamo Biosciences Inc Targeted integration and expression of exogenous nucleic acid sequences
US20110030072A1 (en) * 2008-12-04 2011-02-03 Sigma-Aldrich Co. Genome editing of immunodeficiency genes in animals
US20110016546A1 (en) 2008-12-04 2011-01-20 Sigma-Aldrich Co. Porcine genome editing with zinc finger nucleases
JP2014501097A (en) * 2009-07-06 2014-01-20 アルナイラム ファーマシューティカルズ， インコーポレイテッド Composition and method for enhancing production of biological material
CN102858985A (en) * 2009-07-24 2013-01-02 西格马-奥尔德里奇有限责任公司 Method for genome editing
WO2011103137A1 (en) * 2010-02-17 2011-08-25 Alnylam Pharmaceuticals, Inc. Cell-based methods and reagents
CN107267459A (en) * 2011-01-06 2017-10-20 约翰·霍普金斯大学 The method that the recombinant glycoprotein of the circulating half-life with extension is produced in mammalian cell
ES2733248T3 (en) * 2012-01-11 2019-11-28 Sigma Aldrich Co Llc Production of recombinant proteins with simple glycoforms
SG10201807208RA (en) 2014-03-04 2018-09-27 Sigma Aldrich Co Llc Viral resistant cells and uses thereof

Also Published As

Publication number Publication date
IL247460A0 (en) 2016-11-30
ES2797050T3 (en) 2020-12-01
JP6751347B2 (en) 2020-09-02
JP2020202847A (en) 2020-12-24
SG10201807208RA (en) 2018-09-27
BR112016020287A2 (en) 2017-10-24
BR112016020287B1 (en) 2022-06-28
CN111849921A (en) 2020-10-30
IL276679A (en) 2020-09-30
US20160369240A1 (en) 2016-12-22
IL247460B (en) 2020-08-31
CN106661569A (en) 2017-05-10
EP3114222B1 (en) 2020-04-22
EP3736325A1 (en) 2020-11-11
JP2017506903A (en) 2017-03-16
KR20160127780A (en) 2016-11-04
WO2015134488A1 (en) 2015-09-11
KR20220013460A (en) 2022-02-04
IL276679B (en) 2022-02-01
US10377990B2 (en) 2019-08-13
EP3114222A4 (en) 2017-08-02
KR102354633B1 (en) 2022-01-24
EP3114222A1 (en) 2017-01-11
CN106661569B (en) 2020-09-11

Similar Documents

Publication Publication Date Title
IL276679B (en) Viral resistant cells and uses thereof
IL274903A (en) Cell
IL253248A0 (en) Natural killer cells and uses thereof
HK1231471A1 (en) 6-heteroaryloxy- and 6-aryloxy-quinoline-2-carboxamides and uses thereof 6-- 6--2-
IL252216B (en) Difluoromethyl-aminopyridines and difluoromethyl-aminopyrimidines
GB201405834D0 (en) Oncolytic virus
GB2548059B (en) Induced hepatocytes and uses thereof
HUE044571T2 (en) Modified cyclopentapeptides and uses thereof
LT3131577T (en) Modified host cells and uses thereof
HK1258093A1 (en) Viral neoepitopes and uses thereof
SG11201610514SA (en) Bioreactor and uses thereof
PL3149792T3 (en) Lithium-sulphur cell
GB201604427D0 (en) Modified cell
GB201416316D0 (en) Tile stay and tile plates
GB201410934D0 (en) T cell
GB201404728D0 (en) Disc-over incorporating disc-heads and disc-earning