SG11201605825WA - Stable compositions of peptide epoxy ketones - Google Patents

Stable compositions of peptide epoxy ketones

Info

Publication number
SG11201605825WA
SG11201605825WA SG11201605825WA SG11201605825WA SG11201605825WA SG 11201605825W A SG11201605825W A SG 11201605825WA SG 11201605825W A SG11201605825W A SG 11201605825WA SG 11201605825W A SG11201605825W A SG 11201605825WA SG 11201605825W A SG11201605825W A SG 11201605825WA
Authority
SG
Singapore
Prior art keywords
stable compositions
peptide epoxy
epoxy ketones
ketones
peptide
Prior art date
Application number
SG11201605825WA
Inventor
Ketan Hippalgaonkar
Kumaresh Soppimath
Satish Pejaver
Navneet Puri
Original Assignee
Innopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innopharma Inc filed Critical Innopharma Inc
Publication of SG11201605825WA publication Critical patent/SG11201605825WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
SG11201605825WA 2013-09-10 2014-09-05 Stable compositions of peptide epoxy ketones SG11201605825WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14/023,247 US9636376B2 (en) 2012-09-11 2013-09-10 Stable compositions of peptide epoxy ketones
PCT/US2014/054283 WO2015038431A1 (en) 2013-09-10 2014-09-05 Stable compositions of peptide epoxy ketones

Publications (1)

Publication Number Publication Date
SG11201605825WA true SG11201605825WA (en) 2016-09-29

Family

ID=50233867

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201902826PA SG10201902826PA (en) 2013-09-10 2014-09-05 Stable compositions of peptide epoxy ketones
SG11201605825WA SG11201605825WA (en) 2013-09-10 2014-09-05 Stable compositions of peptide epoxy ketones

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201902826PA SG10201902826PA (en) 2013-09-10 2014-09-05 Stable compositions of peptide epoxy ketones

Country Status (7)

Country Link
US (3) US9636376B2 (en)
EP (1) EP3062883A4 (en)
CA (1) CA2934859A1 (en)
EA (1) EA201691358A1 (en)
SG (2) SG10201902826PA (en)
WO (1) WO2015038431A1 (en)
ZA (1) ZA201604055B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015198257A1 (en) * 2014-06-26 2015-12-30 Intas Pharmaceuticals Ltd. Stable carfilzomib injection
WO2016110870A1 (en) * 2015-01-07 2016-07-14 Emcure Pharmaceuticals Limited Pharmaceutical composition of bortezomid
WO2016116882A2 (en) * 2015-01-23 2016-07-28 Leiutis Pharmaceuticals Pvt Ltd Novel compositions of carfilzomib
WO2016170489A1 (en) * 2015-04-24 2016-10-27 Fresenius Kabi Oncology Ltd. Pharmaceutical compositions of proteasome inhibitor
US10098890B2 (en) 2016-10-29 2018-10-16 Cipla Limited Stable carfilzomib formulations
US11224631B2 (en) 2017-01-24 2022-01-18 Orbicular Pharmaceutical Technologies Pvt. Ltd. Ready-to-use Carfilzomib compositions
GB2562270B (en) * 2017-05-10 2020-07-01 Hyphens Pharma Pte Ltd Skin barrier composition
BR112020009737A2 (en) * 2017-11-16 2020-10-13 Amgen Inc. stable compositions of pegylated carfilzomib compounds
WO2021209947A1 (en) * 2020-04-15 2021-10-21 Kashiv Biosciences, Llc Stable ready to dilute formulations of carfilzomib

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0215355B1 (en) 1985-08-31 1994-04-06 Kitasato Kenkyusho Erythromycin derivative and process for preparing the same
US5133974A (en) 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US20040170724A1 (en) 2003-02-28 2004-09-02 Kraft Foods Holdings, Inc. Mineral complexes of lactobionic acid and method of using for mineral fortification of food products
CN1921772B (en) 2004-02-23 2012-02-22 诺维信公司 Meat based food product comprising lactobionic acid
DK1819353T3 (en) 2004-12-07 2011-05-16 Proteolix Inc Composition for proteasome inhibition
US7589106B2 (en) 2006-09-27 2009-09-15 Eagle Pharmaceuticals, Inc. Alcohol free formulation of argatroban
KR20100088664A (en) * 2007-10-04 2010-08-10 오닉스 세라퓨틱스, 인크. Crystalline peptide epoxy ketone protease inhibitors and the synthesis of amino acid keto-epoxides
CN101624412B (en) 2008-07-10 2012-07-04 刘力 Derivative of macrolides, method for preparing same and application thereof
US8263578B2 (en) 2010-03-18 2012-09-11 Innopharma, Inc. Stable bortezomib formulations
EA201390144A1 (en) * 2010-08-20 2013-06-28 Серулин Фарма Инк. CONJUGATES THERAPEUTIC PEPTIDE POLYMER, PARTICLES, COMPOSITIONS AND RELATED METHODS
WO2013112601A1 (en) 2012-01-24 2013-08-01 Millennium Pharmaceuticals, Inc. Methods of treatment of cancer
FI3922241T3 (en) * 2013-02-01 2023-11-28 Celator Pharmaceuticals Inc Remote loading of sparingly water-soluble drugs into liposomes

Also Published As

Publication number Publication date
EP3062883A1 (en) 2016-09-07
WO2015038431A1 (en) 2015-03-19
US20140073583A1 (en) 2014-03-13
US9636376B2 (en) 2017-05-02
SG10201902826PA (en) 2019-04-29
US20190060393A1 (en) 2019-02-28
EA201691358A1 (en) 2016-11-30
EP3062883A4 (en) 2017-08-16
US20170202901A1 (en) 2017-07-20
ZA201604055B (en) 2018-11-28
CA2934859A1 (en) 2015-03-19

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