SG11201605597VA - Duocarmycin adcs for use in treatment of endometrial cancer - Google Patents
Duocarmycin adcs for use in treatment of endometrial cancerInfo
- Publication number
- SG11201605597VA SG11201605597VA SG11201605597VA SG11201605597VA SG11201605597VA SG 11201605597V A SG11201605597V A SG 11201605597VA SG 11201605597V A SG11201605597V A SG 11201605597VA SG 11201605597V A SG11201605597V A SG 11201605597VA SG 11201605597V A SG11201605597V A SG 11201605597VA
- Authority
- SG
- Singapore
- Prior art keywords
- treatment
- endometrial cancer
- duocarmycin
- adcs
- duocarmycin adcs
- Prior art date
Links
- 206010014733 Endometrial cancer Diseases 0.000 title 1
- 206010014759 Endometrial neoplasm Diseases 0.000 title 1
- VQNATVDKACXKTF-XELLLNAOSA-N duocarmycin Chemical compound COC1=C(OC)C(OC)=C2NC(C(=O)N3C4=CC(=O)C5=C([C@@]64C[C@@H]6C3)C=C(N5)C(=O)OC)=CC2=C1 VQNATVDKACXKTF-XELLLNAOSA-N 0.000 title 1
- 229960005501 duocarmycin Drugs 0.000 title 1
- 229930184221 duocarmycin Natural products 0.000 title 1
Classifications
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Oncology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Reproductive Health (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14150791 | 2014-01-10 | ||
PCT/EP2015/050332 WO2015104373A2 (en) | 2014-01-10 | 2015-01-09 | Duocarmycin adcs for use in treatment of endometrial cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201605597VA true SG11201605597VA (en) | 2016-08-30 |
Family
ID=49917013
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201605597VA SG11201605597VA (en) | 2014-01-10 | 2015-01-09 | Duocarmycin adcs for use in treatment of endometrial cancer |
Country Status (20)
Country | Link |
---|---|
US (2) | US9427480B2 (en) |
EP (1) | EP2948183B1 (en) |
JP (1) | JP6224268B2 (en) |
KR (2) | KR20220045075A (en) |
CN (1) | CN105899237B (en) |
AU (1) | AU2015205588B2 (en) |
CA (1) | CA2935430C (en) |
CL (1) | CL2016001743A1 (en) |
CY (1) | CY1117712T1 (en) |
DK (1) | DK2948183T3 (en) |
ES (1) | ES2578831T3 (en) |
HR (1) | HRP20160797T1 (en) |
HU (1) | HUE029672T2 (en) |
MX (1) | MX368234B (en) |
MY (1) | MY189713A (en) |
PL (1) | PL2948183T3 (en) |
PT (1) | PT2948183T (en) |
RU (1) | RU2686085C2 (en) |
SG (1) | SG11201605597VA (en) |
WO (1) | WO2015104373A2 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9901567B2 (en) | 2007-08-01 | 2018-02-27 | Syntarga B.V. | Substituted CC-1065 analogs and their conjugates |
PT2344478T (en) | 2008-11-03 | 2017-11-28 | Syntarga Bv | Cc-1065 analogs and their conjugates |
CA2796712C (en) | 2010-04-21 | 2017-02-28 | Syntarga B.V. | Novel conjugates of cc-1065 analogs and bifunctional linkers |
PL3092010T3 (en) | 2014-01-10 | 2019-01-31 | Synthon Biopharmaceuticals B.V. | Method for purifying cys-linked antibody-drug conjugates |
JP6224268B2 (en) | 2014-01-10 | 2017-11-01 | シントン・バイオファーマシューティカルズ・ビー.ブイ.Synthon Biopharmaceuticals B.V. | Duocarmycin ADC for use in the treatment of endometrial cancer |
MX368396B (en) | 2014-01-10 | 2019-10-01 | Synthon Biopharmaceuticals Bv | Duocarmycin adcs showing improved in vivo antitumor activity. |
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