SG11201603119RA - Oncolytic hsv vector - Google Patents
Oncolytic hsv vectorInfo
- Publication number
- SG11201603119RA SG11201603119RA SG11201603119RA SG11201603119RA SG11201603119RA SG 11201603119R A SG11201603119R A SG 11201603119RA SG 11201603119R A SG11201603119R A SG 11201603119RA SG 11201603119R A SG11201603119R A SG 11201603119RA SG 11201603119R A SG11201603119R A SG 11201603119RA
- Authority
- SG
- Singapore
- Prior art keywords
- hsv vector
- oncolytic hsv
- oncolytic
- vector
- hsv
- Prior art date
Links
- 230000000174 oncolytic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/763—Herpes virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16621—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16632—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16641—Use of virus, viral particle or viral elements as a vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16641—Use of virus, viral particle or viral elements as a vector
- C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16641—Use of virus, viral particle or viral elements as a vector
- C12N2710/16645—Special targeting system for viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16661—Methods of inactivation or attenuation
- C12N2710/16662—Methods of inactivation or attenuation by genetic engineering
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16671—Demonstrated in vivo effect
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361896497P | 2013-10-28 | 2013-10-28 | |
| PCT/US2014/062676 WO2015066042A1 (en) | 2013-10-28 | 2014-10-28 | Oncolytic hsv vector |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201603119RA true SG11201603119RA (en) | 2016-05-30 |
Family
ID=53005031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201603119RA SG11201603119RA (en) | 2013-10-28 | 2014-10-28 | Oncolytic hsv vector |
Country Status (18)
| Country | Link |
|---|---|
| US (5) | US10201575B2 (en) |
| EP (3) | EP3063279B1 (en) |
| JP (3) | JP6588024B2 (en) |
| KR (2) | KR102490462B1 (en) |
| CN (2) | CN113717952A (en) |
| AU (1) | AU2014342465B2 (en) |
| BR (1) | BR112016009465A8 (en) |
| CA (1) | CA2928956A1 (en) |
| DK (1) | DK3184641T3 (en) |
| ES (2) | ES2781852T3 (en) |
| HK (1) | HK1225756A1 (en) |
| IL (2) | IL245312B (en) |
| MX (2) | MX2016005488A (en) |
| NZ (1) | NZ720021A (en) |
| PT (1) | PT3184641T (en) |
| RU (1) | RU2719190C2 (en) |
| SG (1) | SG11201603119RA (en) |
| WO (1) | WO2015066042A1 (en) |
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| US9593347B2 (en) | 2010-04-16 | 2017-03-14 | University of Pittsburgh—of the Commonwealth System of Higher Education | Identification of mutations in herpes simplex virus envelope glycoproteins that enable or enhance vector retargeting to novel non-HSV receptors |
| ES2781852T3 (en) | 2013-10-28 | 2020-09-08 | Univ Pittsburgh Commonwealth Sys Higher Education | Oncolytic HSV vector |
| HUE054563T2 (en) * | 2015-02-11 | 2021-09-28 | Univ Bologna Alma Mater Studiorum | Retargeted herpesvirus with a glycoprotein h fusion |
| JP2019508063A (en) | 2016-01-27 | 2019-03-28 | オンコラス， インコーポレイテッド | Oncolytic virus vector and use thereof |
| IL261713B2 (en) * | 2016-03-19 | 2023-09-01 | F1 Oncology Inc | Methods and compositions for transducing lymphocytes and regulated expansion thereof |
| US11325948B2 (en) | 2016-03-19 | 2022-05-10 | Exuma Biotech Corp. | Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL |
| EP3712273A1 (en) * | 2016-04-08 | 2020-09-23 | Krystal Biotech, LLC | Compositions for the treatment of wounds, disorders, and diseases of the skin |
| IL262385B2 (en) | 2016-04-22 | 2024-01-01 | Immvira Co Ltd | CONSTRUCTION OF ONCOLYTIC HERPES SIMPLEX VIRUSES (oHSV) OBLIGATE VECTOR AND CONSTRUCTS FOR CANCER THERAPY |
| ES2904882T3 (en) * | 2016-04-29 | 2022-04-06 | Virogin Biotech Canada Ltd | HSV vectors with enhanced replication in cancer cells |
| KR20190020727A (en) | 2016-06-09 | 2019-03-04 | 알마마 테르 스투디오룸 유니베르시타‘ 디 볼로냐 | Herpes virus with modified glycoprotein B |
| ES2862531T3 (en) | 2016-06-09 | 2021-10-07 | Univ Bologna Alma Mater Studiorum | Herpes virus with modified D glycoprotein |
| EP3468588A4 (en) * | 2016-06-14 | 2019-12-11 | University of Pittsburgh - of The Commonwealth System of Higher Education | Expression of nkg2d activating ligand proteins for sensitizing cancer cells to attack by cytotoxic immune cells |
| RU2021127872A (en) | 2016-06-30 | 2021-11-09 | Онкорус, Инк. | DELIVERY OF THERAPEUTIC POLYPEPTIDES THROUGH PSEUDOTYPED ONCOLYTIC VIRUSES |
| GB201616365D0 (en) * | 2016-09-27 | 2016-11-09 | Helsingin Yliopisto | Non-genetic modification of enveloped viruses |
| GB201700350D0 (en) * | 2017-01-09 | 2017-02-22 | Replimune Ltd | Altered virus |
| EP3577132A4 (en) * | 2017-02-03 | 2021-03-10 | University of Pittsburgh - of The Commonwealth System of Higher Education | Oncolytic virus therapy |
| CN115820571A (en) * | 2017-03-09 | 2023-03-21 | 厦门大学 | Recombinant herpes simplex virus and application thereof |
| CA3070299A1 (en) * | 2017-07-26 | 2019-01-31 | Oncorus, Inc. | Oncolytic viral vectors and uses thereof |
| GB201714430D0 (en) * | 2017-09-07 | 2017-10-25 | Micol Romain | Compositions and processes for targeted delivery and expression and modulation of therapeutic components in tissue |
| US20210177921A1 (en) * | 2017-11-16 | 2021-06-17 | Virogin Biotech Canada Ltd | Targeting moiety-decorated oncolytic viruses |
| JP2021508477A (en) | 2017-12-29 | 2021-03-11 | オンコラス， インコーポレイテッド | Oncolytic virus delivery of therapeutic polypeptides |
| MA52542A (en) * | 2018-04-13 | 2021-02-24 | Bluebird Bio Inc | ADOPTIVE CELL THERAPY |
| AU2019277669A1 (en) * | 2018-05-31 | 2020-12-17 | Trustees Of The University Of Pennsylvania | Antigenically stealthed oncolytic viruses |
| KR101998793B1 (en) * | 2018-09-04 | 2019-07-10 | 의료법인 성광의료재단 | A vector for preparing recombinant herpes simplex virus |
| CN111117973A (en) * | 2018-10-30 | 2020-05-08 | 中国科学院武汉病毒研究所 | Recombinant oncolytic enterovirus 71 regulated and controlled by microRNA and application thereof |
| TW202038947A (en) | 2018-11-28 | 2020-11-01 | 德商創新分子有限責任公司 | Helicase primase inhibitors for treating cancer in a combination therapy with oncolytic viruses |
| WO2021072310A1 (en) | 2019-10-10 | 2021-04-15 | Oncorus, Inc. | Dual viruses and dual oncolytic viruses and methods of treatment |
| KR20210151002A (en) * | 2020-06-03 | 2021-12-13 | 주식회사 젠셀메드 | Recombinant Herpes Simplex Virus Containing Expression Cassette Expressing a Fused Protein of Extracellular Damain of HveC and Tumor Cell-targeting Domain and Use of the Same |
| KR102418528B1 (en) * | 2020-06-12 | 2022-07-11 | 주식회사 젠셀메드 | Recombinant Herpes Simplex Virus Containing Expression Cassette Expressing a Fused Protein of Tumor Cell-targeting Domain and Extracellular Damain of HVEM and Use of the Same |
| JP7235334B2 (en) * | 2020-11-26 | 2023-03-08 | イムヴィラ・カンパニー・リミテッド | Construction of oncolytic herpes simplex virus (oHSV) obligate vectors and their constructs for cancer therapy |
| CA3213789A1 (en) | 2021-04-02 | 2022-10-06 | Krystal Biotech, Inc. | Viral vectors for cancer therapy |
| TW202342758A (en) * | 2022-01-29 | 2023-11-01 | 加拿大商復諾健生物科技加拿大有限公司 | Transcriptional and translational dual regulated oncolytic herpes simplex virus vectors |
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| US5244792A (en) | 1984-04-06 | 1993-09-14 | Chiron Corporation | Expression of recombinant glyoprotein B from herpes simplex virus |
| JPH0668B2 (en) | 1985-08-30 | 1994-01-05 | 財団法人化学及血清療法研究所 | Recombinant plasmid with herpes simplex virus gene |
| US5849572A (en) | 1990-10-10 | 1998-12-15 | Regents Of The University Of Michigan | HSV-1 vector containing a lat promoter |
| US5804413A (en) | 1992-07-31 | 1998-09-08 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Herpes simplex virus strains for gene transfer |
| US5879934A (en) | 1992-07-31 | 1999-03-09 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Herpes simplex virus strains for gene transfer |
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| US6261552B1 (en) | 1997-05-22 | 2001-07-17 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Herpes simplex virus vectors |
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| AU8605598A (en) | 1997-07-31 | 1999-02-22 | University Of Pittsburgh | Targeted hsv vectors |
| WO1999031241A1 (en) | 1997-12-17 | 1999-06-24 | Immunex Corporation | Cell surface glycoproteins associated with human b cell lymphomas - ulbp, dna and polypeptides |
| EP1002864A1 (en) | 1998-11-10 | 2000-05-24 | Universita' degli studi di Bologna | HIgR and related V domain for the manufacture of a medicament for preventing or treating HSV-1, HSV-2 and BHV infections |
| US6897057B1 (en) * | 1999-08-31 | 2005-05-24 | The General Hospital Corporation | Cell-specific and/or tumor-specific promoter retargeting of herpes γ 34.5 gene expression |
| GB9930418D0 (en) | 1999-12-22 | 2000-02-16 | Neurovex Ltd | Replication incompetent herpes virus vectors |
| ATE508635T1 (en) * | 2001-03-27 | 2011-05-15 | Catherex Inc | VIRUS VECTORS AND THEIR USE IN THERAPEUTIC METHODS |
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| WO2003073918A2 (en) | 2002-03-01 | 2003-09-12 | Sloan-Kettering Institute For Cancer Research | Prevention of recurrence and metastasis of cancer |
| US8927251B2 (en) | 2002-10-07 | 2015-01-06 | The University Of Chicago | Targeting of herpes simplex virus to specific receptors |
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| EP2377882A1 (en) | 2004-10-28 | 2011-10-19 | University of Pittsburgh of the Commonwealth System of Higher Education | Peripherally delivered glutamatic acid decarboxylase gene therapy for spinal cord injury pain |
| US10000757B2 (en) | 2005-05-27 | 2018-06-19 | Ospedale San Raffaele S.R.L. | Gene vector |
| US20080008686A1 (en) | 2006-07-10 | 2008-01-10 | The Brigham And Women's Hospital, Inc. | Tetracycline repressor regulated oncolytic viruses |
| US8586028B2 (en) | 2007-05-09 | 2013-11-19 | Board Of Supervisors Of Lousiana State University And Agricultural And Mechanical College | Synthetic herpes simplex viruses type-1 for treatment of cancers |
| US20080289058A1 (en) | 2007-05-14 | 2008-11-20 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Targeted delivery of glycine receptors to excitable cells |
| WO2009111892A1 (en) | 2008-03-14 | 2009-09-17 | Ottawa Health Research Institute | Microrna mediated oncolytic targeting |
| WO2009148488A2 (en) | 2008-05-29 | 2009-12-10 | The General Hospital Corporation | Use of oncolytic herpes viruses for killing cancer stem cells |
| DK2700405T3 (en) * | 2008-05-29 | 2018-05-22 | Univ Bologna Alma Mater Studiorum | Herpes simplex virus (HSV) with modified tropism, its uses and method of preparation |
| GB0810912D0 (en) * | 2008-06-13 | 2008-07-23 | Inst Animal Health Ltd | Vector |
| US8569065B2 (en) | 2009-03-13 | 2013-10-29 | Egen, Inc. | Compositions and methods for the delivery of biologically active RNAs |
| WO2011125469A1 (en) | 2010-04-09 | 2011-10-13 | 国立大学法人東京大学 | Micro-rna-regulated recombinant vaccinia virus and utilization thereof |
| US9593347B2 (en) | 2010-04-16 | 2017-03-14 | University of Pittsburgh—of the Commonwealth System of Higher Education | Identification of mutations in herpes simplex virus envelope glycoproteins that enable or enhance vector retargeting to novel non-HSV receptors |
| WO2012006181A2 (en) | 2010-06-29 | 2012-01-12 | Mount Sinai School Of Medicine | Compositions and methods for inhibiting oncogenic micrornas and treatment of cancer |
| US20130156808A1 (en) | 2011-11-22 | 2013-06-20 | Stipan Jonjic | Vaccine comprising beta-herpesvirus |
| CN105637092B (en) | 2013-07-17 | 2021-06-11 | 匹兹堡大学-属高等教育联邦体系 | Non-toxic HSV vectors for efficient gene delivery applications and complementing cells for their production |
| ES2781852T3 (en) | 2013-10-28 | 2020-09-08 | Univ Pittsburgh Commonwealth Sys Higher Education | Oncolytic HSV vector |
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2014
- 2014-10-28 ES ES14859119T patent/ES2781852T3/en active Active
- 2014-10-28 PT PT171551294T patent/PT3184641T/en unknown
- 2014-10-28 US US15/032,958 patent/US10201575B2/en active Active
- 2014-10-28 MX MX2016005488A patent/MX2016005488A/en unknown
- 2014-10-28 WO PCT/US2014/062676 patent/WO2015066042A1/en active Application Filing
- 2014-10-28 DK DK17155129.4T patent/DK3184641T3/en active
- 2014-10-28 KR KR1020217037699A patent/KR102490462B1/en active IP Right Grant
- 2014-10-28 NZ NZ720021A patent/NZ720021A/en unknown
- 2014-10-28 EP EP14859119.1A patent/EP3063279B1/en active Active
- 2014-10-28 KR KR1020167012961A patent/KR102330183B1/en active IP Right Grant
- 2014-10-28 CA CA2928956A patent/CA2928956A1/en active Pending
- 2014-10-28 EP EP17155129.4A patent/EP3184641B1/en active Active
- 2014-10-28 ES ES17155129T patent/ES2810800T3/en active Active
- 2014-10-28 BR BR112016009465A patent/BR112016009465A8/en not_active Application Discontinuation
- 2014-10-28 EP EP20184441.2A patent/EP3778906A1/en active Pending
- 2014-10-28 AU AU2014342465A patent/AU2014342465B2/en active Active
- 2014-10-28 CN CN202110609000.1A patent/CN113717952A/en active Pending
- 2014-10-28 RU RU2016120618A patent/RU2719190C2/en active
- 2014-10-28 JP JP2016552209A patent/JP6588024B2/en active Active
- 2014-10-28 CN CN201480071446.1A patent/CN106068326B/en active Active
- 2014-10-28 SG SG11201603119RA patent/SG11201603119RA/en unknown
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2016
- 2016-04-25 IL IL245312A patent/IL245312B/en active IP Right Grant
- 2016-04-27 MX MX2021001158A patent/MX2021001158A/en unknown
- 2016-07-07 US US15/204,350 patent/US10188686B2/en active Active
- 2016-12-14 HK HK16114198A patent/HK1225756A1/en unknown
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2017
- 2017-06-07 US US15/616,585 patent/US10172893B2/en active Active
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2018
- 2018-11-14 US US16/191,141 patent/US10576115B2/en active Active
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2019
- 2019-09-11 JP JP2019165005A patent/JP6919912B2/en active Active
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2020
- 2020-02-05 IL IL272480A patent/IL272480B/en active IP Right Grant
- 2020-08-05 US US16/985,459 patent/US11883448B2/en active Active
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2021
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