SG11201600991QA - V1a antagonists to treat phase shift sleep disorders - Google Patents

V1a antagonists to treat phase shift sleep disorders

Info

Publication number
SG11201600991QA
SG11201600991QA SG11201600991QA SG11201600991QA SG11201600991QA SG 11201600991Q A SG11201600991Q A SG 11201600991QA SG 11201600991Q A SG11201600991Q A SG 11201600991QA SG 11201600991Q A SG11201600991Q A SG 11201600991QA SG 11201600991Q A SG11201600991Q A SG 11201600991QA
Authority
SG
Singapore
Prior art keywords
antagonists
phase shift
sleep disorders
shift sleep
treat phase
Prior art date
Application number
SG11201600991QA
Inventor
Patrick Schnider
Christophe Grundschober
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SG11201600991QA publication Critical patent/SG11201600991QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dermatology (AREA)
SG11201600991QA 2013-08-19 2014-08-12 V1a antagonists to treat phase shift sleep disorders SG11201600991QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13180836 2013-08-19
PCT/EP2014/067264 WO2015024819A1 (en) 2013-08-19 2014-08-12 V1a antagonists to treat phase shift sleep disorders

Publications (1)

Publication Number Publication Date
SG11201600991QA true SG11201600991QA (en) 2016-03-30

Family

ID=48985673

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201600991QA SG11201600991QA (en) 2013-08-19 2014-08-12 V1a antagonists to treat phase shift sleep disorders

Country Status (21)

Country Link
US (1) US10265327B2 (en)
EP (1) EP3035939B1 (en)
JP (1) JP6427192B2 (en)
KR (1) KR20160042903A (en)
CN (1) CN105492010B (en)
AU (1) AU2014310733A1 (en)
BR (1) BR112016001948A2 (en)
CA (1) CA2919738A1 (en)
CL (1) CL2016000325A1 (en)
CR (1) CR20160042A (en)
EA (1) EA201690179A1 (en)
ES (1) ES2793929T3 (en)
HK (1) HK1217171A1 (en)
IL (1) IL243387A0 (en)
MA (1) MA38867A1 (en)
MX (1) MX2016001940A (en)
PE (1) PE20160203A1 (en)
PH (1) PH12016500124A1 (en)
PL (1) PL3035939T3 (en)
SG (1) SG11201600991QA (en)
WO (1) WO2015024819A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105793263B (en) * 2013-12-05 2019-08-23 豪夫迈·罗氏有限公司 A kind of synthesis of benzo [E] Azulene compound and its crystal form
WO2017191117A1 (en) 2016-05-03 2017-11-09 Bayer Pharma Aktiengesellschaft V1a receptor antagonists for use in the treatment of renal diseases
WO2018133835A1 (en) * 2017-01-20 2018-07-26 National Institute Of Biological Sciences, Beijing Nucleoside analogue regulating mammalian circadian rhythm
MX2020004105A (en) * 2017-12-08 2020-09-22 Hoffmann La Roche Pharmaceutical formulation.
JP2023534721A (en) * 2020-07-23 2023-08-10 エフ. ホフマン-ラ ロシュ アーゲー Heteroaryl-methyl-substituted triazoles as vasopressin receptor V1A antagonists
EP4185570A1 (en) * 2020-07-23 2023-05-31 F. Hoffmann-La Roche AG Cyclohexyl substituted triazoles as vasopressin receptor v1 a antagonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60132611T2 (en) * 2000-10-27 2009-02-19 Ortho-Mcneil Pharmaceutical, Inc. SUBSTITUTED BENZIMIDAZOLE-2-ONE AS VASOPRESSIN RECEPTOR ANTAGONISTS AND NEUROPEPTIDE Y MODULATORS
CA2469790A1 (en) * 2001-12-17 2003-06-26 Merck & Co., Inc. Method for treating circadian rhythm disruptions
GB0303852D0 (en) * 2003-02-19 2003-03-26 Pfizer Ltd Triazole compounds useful in therapy
BRPI0514458A (en) * 2004-08-25 2008-06-10 Pfizer triazolbenzodiazepines and their use as vasopressin antagonists
DK2370441T3 (en) * 2008-11-28 2013-10-21 Hoffmann La Roche ARYLCYCLOHEXYLETHERS OF DIHYDROTETRAAZABENZOAZULENES USED AS VASOPRESSIN V1A RECEPTOR ANTAGONISTS
JPWO2013176220A1 (en) * 2012-05-25 2016-01-14 国立大学法人京都大学 Circadian rhythm adjustment

Also Published As

Publication number Publication date
US20180064727A1 (en) 2018-03-08
IL243387A0 (en) 2016-02-29
ES2793929T3 (en) 2020-11-17
KR20160042903A (en) 2016-04-20
CL2016000325A1 (en) 2016-09-30
PE20160203A1 (en) 2016-04-20
PH12016500124A1 (en) 2016-04-25
MA38867A1 (en) 2018-01-31
MX2016001940A (en) 2016-06-02
WO2015024819A1 (en) 2015-02-26
EP3035939A1 (en) 2016-06-29
CR20160042A (en) 2016-04-01
CN105492010B (en) 2020-01-03
CN105492010A (en) 2016-04-13
US10265327B2 (en) 2019-04-23
BR112016001948A2 (en) 2017-08-01
JP2016528266A (en) 2016-09-15
EP3035939B1 (en) 2020-03-25
EA201690179A1 (en) 2016-06-30
JP6427192B2 (en) 2018-11-21
PL3035939T3 (en) 2020-07-27
HK1217171A1 (en) 2016-12-30
CA2919738A1 (en) 2015-02-26
AU2014310733A1 (en) 2016-02-04

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