SG11201600736SA - Expression constructs and methods for expressing polypeptides in eukaryotic cells - Google Patents
Expression constructs and methods for expressing polypeptides in eukaryotic cellsInfo
- Publication number
- SG11201600736SA SG11201600736SA SG11201600736SA SG11201600736SA SG11201600736SA SG 11201600736S A SG11201600736S A SG 11201600736SA SG 11201600736S A SG11201600736S A SG 11201600736SA SG 11201600736S A SG11201600736S A SG 11201600736SA SG 11201600736S A SG11201600736S A SG 11201600736SA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- eukaryotic cells
- expression constructs
- expressing polypeptides
- polypeptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
- C12N2840/445—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor for trans-splicing, e.g. polypyrimidine tract, branch point splicing
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13179375 | 2013-08-06 | ||
| PCT/EP2014/066826 WO2015018832A1 (en) | 2013-08-06 | 2014-08-05 | Expression constructs and methods for expressing polypeptides in eukaryotic cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201600736SA true SG11201600736SA (en) | 2016-02-26 |
Family
ID=51300736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201600736SA SG11201600736SA (en) | 2013-08-06 | 2014-08-05 | Expression constructs and methods for expressing polypeptides in eukaryotic cells |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20150056655A1 (en) |
| EP (1) | EP3030579A1 (en) |
| JP (3) | JP2016528896A (en) |
| KR (2) | KR20200044154A (en) |
| CN (1) | CN105658665A (en) |
| AU (2) | AU2014304570B2 (en) |
| BR (1) | BR112016002319A2 (en) |
| CA (1) | CA2920574C (en) |
| EA (1) | EA201690271A1 (en) |
| IL (2) | IL243967A0 (en) |
| MX (1) | MX2016001678A (en) |
| NZ (1) | NZ717178A (en) |
| SG (1) | SG11201600736SA (en) |
| WO (1) | WO2015018832A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016315892B2 (en) * | 2015-09-02 | 2023-06-15 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for modulating T-cell mediated immune response |
| CA3135490A1 (en) * | 2019-03-29 | 2020-10-08 | Salk Institute For Biological Studies | High-efficiency reconstitution of rna molecules |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6136566A (en) * | 1996-10-04 | 2000-10-24 | Lexicon Graphics Incorporated | Indexed library of cells containing genomic modifications and methods of making and utilizing the same |
| US20040072243A1 (en) * | 1996-10-11 | 2004-04-15 | Lexicon Genetics Incorporated | Indexed library of cells containing genomic modifications and methods of making and utilizing the same |
| CA2559280A1 (en) * | 2004-03-15 | 2005-09-29 | Biogen Idec Ma Inc. | Methods and constructs for expressing polypeptide multimers in eukaryotic cells using alternative splicing |
| WO2007135515A1 (en) * | 2006-05-16 | 2007-11-29 | Millegen | Method for expressing polypeptides in eukaryotic cells using alternative splicing |
| JP5875009B2 (en) * | 2010-06-01 | 2016-03-02 | 国立大学法人京都大学 | Transgenic reporter system reveals alternative splicing expression profiles and regulatory mechanisms in mammalian organisms |
-
2014
- 2014-08-05 AU AU2014304570A patent/AU2014304570B2/en active Active
- 2014-08-05 CA CA2920574A patent/CA2920574C/en active Active
- 2014-08-05 SG SG11201600736SA patent/SG11201600736SA/en unknown
- 2014-08-05 MX MX2016001678A patent/MX2016001678A/en unknown
- 2014-08-05 WO PCT/EP2014/066826 patent/WO2015018832A1/en active Application Filing
- 2014-08-05 BR BR112016002319A patent/BR112016002319A2/en not_active Application Discontinuation
- 2014-08-05 CN CN201480055196.2A patent/CN105658665A/en active Pending
- 2014-08-05 EP EP14749786.1A patent/EP3030579A1/en not_active Withdrawn
- 2014-08-05 EA EA201690271A patent/EA201690271A1/en unknown
- 2014-08-05 NZ NZ717178A patent/NZ717178A/en unknown
- 2014-08-05 KR KR1020207011393A patent/KR20200044154A/en not_active Application Discontinuation
- 2014-08-05 KR KR1020167006036A patent/KR102104581B1/en active IP Right Grant
- 2014-08-05 JP JP2016532665A patent/JP2016528896A/en active Pending
- 2014-08-06 US US14/453,328 patent/US20150056655A1/en not_active Abandoned
-
2016
- 2016-02-04 IL IL243967A patent/IL243967A0/en unknown
- 2016-11-17 US US15/354,907 patent/US20170253671A1/en not_active Abandoned
-
2019
- 2019-07-16 US US16/512,482 patent/US20200172634A1/en active Pending
- 2019-09-10 IL IL26925219A patent/IL269252A/en unknown
- 2019-09-23 AU AU2019236586A patent/AU2019236586B2/en active Active
-
2020
- 2020-07-17 JP JP2020122925A patent/JP2020202840A/en active Pending
-
2022
- 2022-09-12 JP JP2022144740A patent/JP2022177131A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20160035084A (en) | 2016-03-30 |
| AU2019236586B2 (en) | 2020-12-03 |
| IL269252A (en) | 2019-11-28 |
| JP2022177131A (en) | 2022-11-30 |
| NZ717178A (en) | 2022-02-25 |
| CA2920574A1 (en) | 2015-02-12 |
| IL243967A0 (en) | 2016-04-21 |
| US20200172634A1 (en) | 2020-06-04 |
| BR112016002319A2 (en) | 2017-09-12 |
| CA2920574C (en) | 2021-03-16 |
| KR102104581B1 (en) | 2020-06-02 |
| AU2014304570A1 (en) | 2016-03-10 |
| CN105658665A (en) | 2016-06-08 |
| MX2016001678A (en) | 2016-10-28 |
| AU2019236586A1 (en) | 2019-10-10 |
| EP3030579A1 (en) | 2016-06-15 |
| WO2015018832A1 (en) | 2015-02-12 |
| EA201690271A1 (en) | 2016-07-29 |
| AU2014304570B2 (en) | 2019-07-25 |
| US20150056655A1 (en) | 2015-02-26 |
| JP2020202840A (en) | 2020-12-24 |
| JP2016528896A (en) | 2016-09-23 |
| KR20200044154A (en) | 2020-04-28 |
| US20170253671A1 (en) | 2017-09-07 |
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