SG11201510764QA - Dihydroxyphenyl neurotransmitter compounds, compositions and methods - Google Patents
Dihydroxyphenyl neurotransmitter compounds, compositions and methodsInfo
- Publication number
- SG11201510764QA SG11201510764QA SG11201510764QA SG11201510764QA SG11201510764QA SG 11201510764Q A SG11201510764Q A SG 11201510764QA SG 11201510764Q A SG11201510764Q A SG 11201510764QA SG 11201510764Q A SG11201510764Q A SG 11201510764QA SG 11201510764Q A SG11201510764Q A SG 11201510764QA
- Authority
- SG
- Singapore
- Prior art keywords
- dihydroxyphenyl
- compositions
- methods
- neurotransmitter
- compounds
- Prior art date
Links
- -1 Dihydroxyphenyl Chemical group 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000002858 neurotransmitter agent Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Anesthesiology (AREA)
- Nutrition Science (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361843549P | 2013-07-08 | 2013-07-08 | |
US201462010098P | 2014-06-10 | 2014-06-10 | |
PCT/US2014/045731 WO2015006315A1 (en) | 2013-07-08 | 2014-07-08 | Dihydroxyphenyl neurotransmitter compounds, compositions and methods |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201510764QA true SG11201510764QA (en) | 2016-01-28 |
Family
ID=52133230
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201510764QA SG11201510764QA (en) | 2013-07-08 | 2014-07-08 | Dihydroxyphenyl neurotransmitter compounds, compositions and methods |
SG10201800166UA SG10201800166UA (en) | 2013-07-08 | 2014-07-08 | Dihydroxyphenyl neurotransmitter compounds, compositions and methods |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201800166UA SG10201800166UA (en) | 2013-07-08 | 2014-07-08 | Dihydroxyphenyl neurotransmitter compounds, compositions and methods |
Country Status (16)
Country | Link |
---|---|
US (5) | US20150011630A1 (en) |
EP (2) | EP3611159B1 (en) |
JP (1) | JP6567515B2 (en) |
KR (1) | KR20160041912A (en) |
CN (1) | CN105473545B (en) |
AU (2) | AU2014287418A1 (en) |
BR (1) | BR112016000338A8 (en) |
CA (1) | CA2917159C (en) |
CL (1) | CL2016000019A1 (en) |
EA (1) | EA201600093A1 (en) |
HK (2) | HK1216747A1 (en) |
IL (2) | IL243488A0 (en) |
MX (1) | MX2016000219A (en) |
PE (1) | PE20160556A1 (en) |
SG (2) | SG11201510764QA (en) |
WO (1) | WO2015006315A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL288194B2 (en) * | 2016-08-30 | 2024-03-01 | Theravance Biopharma R& D Ip Llc | 4-[2-(2,4,6-trifluorophenoxymethyl) phenyl]piperidine for use in the treatment of neurogenic orthostatic hypotension |
GB2566516A (en) | 2017-09-15 | 2019-03-20 | Univ Oxford Innovation Ltd | Electrochemical recognition and quantification of cytochrome c oxidase expression in bacteria |
GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
KR20220009954A (en) | 2019-04-17 | 2022-01-25 | 컴퍼스 패쓰파인더 리미티드 | Neurocognitive Disorder, How to Treat Chronic Pain and Reduce Inflammation |
EP4048263A4 (en) * | 2019-10-25 | 2023-11-15 | Curasen Therapeutics, Inc. | Methods for treating neurological disorders with alpha 1a-ar partial agonists |
WO2021247963A1 (en) * | 2020-06-05 | 2021-12-09 | Senda Biosciences, Inc. | (s)-alpha-fluoromethyltyrosine as decarboxylase inhibitors for use in the treatment of hypotension |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0084928B1 (en) * | 1982-01-14 | 1985-09-11 | Sumitomo Chemical Company, Limited | Process for producing threo-3-(3,4-dihydroxyphenyl)serine |
CA1223602A (en) | 1983-05-25 | 1987-06-30 | Naohito Ohashi | Process for producing 3-(3,4-dihydroxyphenyl) serine |
JP3764179B2 (en) | 1994-07-05 | 2006-04-05 | 克寛 西野 | Function / function-improving agent for exercise / consciousness |
DE19619510A1 (en) | 1995-05-18 | 1996-11-21 | Sumitomo Chemical Co | Process for the preparation of threo-3- (3,4-dihydroxyphenyl) serine |
JP3489319B2 (en) | 1996-03-12 | 2004-01-19 | 住友化学工業株式会社 | Carboxylic acid derivatives, their production and use |
JPH115738A (en) | 1997-06-15 | 1999-01-12 | Katsuhiro Nishino | Preventive for nerve defluxion symptom followed by cerebral ischemia and therapeutic agent for hyperacute period |
US6376531B1 (en) * | 1998-11-13 | 2002-04-23 | Rupert Charles Bell | Method of treatment using deuterium compounds |
DE10261807A1 (en) * | 2002-12-19 | 2004-07-01 | Turicum Drug Development Ag | Deuterated catecholamine derivatives and medicinal products containing these compounds |
WO2005084330A2 (en) | 2004-03-02 | 2005-09-15 | Synergia Pharma, Inc. | Compositions and methods for treating nasal congestion |
WO2007093450A2 (en) * | 2006-02-17 | 2007-08-23 | Birds Pharma Gmbh Berolina Innovative Research & Development Services | Deuterated catecholamine derivatives and medicaments comprising said compounds |
BRPI0808647A2 (en) | 2007-03-09 | 2014-08-12 | Chelsea Therapeutics Inc | METHOD TO TREAT CENTRAL SENSITIVITY SYNDROME, METHOD TO REDUCE, ELIMINATE OR PREVENT PAIN ASSOCIATED WITH FIBROMYALGY, USEFUL KIT FOR TREATMENT OF CENTRAL SENSITIVITY SYNDROME. |
WO2008112773A2 (en) | 2007-03-12 | 2008-09-18 | Chelsea Therapeutics, Inc. | Droxidopa and pharmaceutical composition thereof for the treatment of neurally mediated hypotension |
ES2431570T3 (en) | 2007-05-07 | 2013-11-27 | Chelsea Therapeutics, Inc. | Droxidopa and its pharmaceutical composition for the treatment of attention deficit disorders |
US7745665B2 (en) | 2007-06-04 | 2010-06-29 | Auspex Pharmaceuticals, Inc. | Substituted phenethylamines |
WO2010054286A2 (en) * | 2008-11-10 | 2010-05-14 | Auspex Pharmaceuticals, Inc. | Substituted hydroxyphenylamine compounds |
US9072730B2 (en) | 2009-05-14 | 2015-07-07 | The Board Of Trustees Of The Leland Stanford Junior University | Method of improving cognitive functions in individuals with down syndrome and/or alzheimer's disease |
US8598370B2 (en) | 2009-07-01 | 2013-12-03 | Dainippon Sumitomo Pharma Co., Ltd. | Process for producing threo-3-(3,4-dihydroxyphenyl)-L-serine |
JP5880913B2 (en) | 2011-05-17 | 2016-03-09 | 三郎 佐古田 | Treatment for trunk symptoms (postural reflex abnormalities) in Parkinson's disease |
US20130253061A1 (en) | 2012-03-20 | 2013-09-26 | Chelsea Therapeutics, Inc. | Method of droxidopa synthesis |
-
2014
- 2014-07-08 PE PE2016000010A patent/PE20160556A1/en unknown
- 2014-07-08 WO PCT/US2014/045731 patent/WO2015006315A1/en active Application Filing
- 2014-07-08 CA CA2917159A patent/CA2917159C/en active Active
- 2014-07-08 EA EA201600093A patent/EA201600093A1/en unknown
- 2014-07-08 SG SG11201510764QA patent/SG11201510764QA/en unknown
- 2014-07-08 JP JP2016525422A patent/JP6567515B2/en active Active
- 2014-07-08 EP EP19188210.9A patent/EP3611159B1/en active Active
- 2014-07-08 BR BR112016000338A patent/BR112016000338A8/en not_active Application Discontinuation
- 2014-07-08 AU AU2014287418A patent/AU2014287418A1/en not_active Abandoned
- 2014-07-08 EP EP14822407.4A patent/EP3019467A4/en not_active Withdrawn
- 2014-07-08 MX MX2016000219A patent/MX2016000219A/en unknown
- 2014-07-08 SG SG10201800166UA patent/SG10201800166UA/en unknown
- 2014-07-08 CN CN201480042918.0A patent/CN105473545B/en not_active Expired - Fee Related
- 2014-07-08 US US14/325,988 patent/US20150011630A1/en not_active Abandoned
- 2014-07-08 KR KR1020167003133A patent/KR20160041912A/en active Search and Examination
-
2016
- 2016-01-05 IL IL243488A patent/IL243488A0/en unknown
- 2016-01-07 CL CL2016000019A patent/CL2016000019A1/en unknown
- 2016-04-21 HK HK16104626.6A patent/HK1216747A1/en not_active IP Right Cessation
- 2016-08-16 HK HK16109787.0A patent/HK1221713A1/en unknown
-
2017
- 2017-07-21 US US15/656,035 patent/US20170319694A1/en not_active Abandoned
-
2018
- 2018-06-06 US US16/000,965 patent/US20180280511A1/en not_active Abandoned
- 2018-10-26 AU AU2018253594A patent/AU2018253594A1/en not_active Abandoned
-
2019
- 2019-05-21 IL IL266767A patent/IL266767A/en unknown
- 2019-08-01 US US16/529,187 patent/US20190374642A1/en not_active Abandoned
-
2021
- 2021-08-11 US US17/399,708 patent/US20220072131A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
PE20160556A1 (en) | 2016-06-11 |
CN105473545B (en) | 2017-08-04 |
BR112016000338A2 (en) | 2017-08-22 |
IL243488A0 (en) | 2016-02-29 |
HK1216747A1 (en) | 2016-12-02 |
US20170319694A1 (en) | 2017-11-09 |
EP3611159B1 (en) | 2023-01-25 |
EP3611159A1 (en) | 2020-02-19 |
IL266767A (en) | 2019-07-31 |
WO2015006315A1 (en) | 2015-01-15 |
EP3019467A1 (en) | 2016-05-18 |
EA201600093A1 (en) | 2016-08-31 |
US20180280511A1 (en) | 2018-10-04 |
AU2018253594A1 (en) | 2018-11-22 |
JP6567515B2 (en) | 2019-08-28 |
AU2014287418A1 (en) | 2016-01-28 |
HK1221713A1 (en) | 2017-06-09 |
MX2016000219A (en) | 2016-05-31 |
CL2016000019A1 (en) | 2016-11-04 |
US20150011630A1 (en) | 2015-01-08 |
CA2917159C (en) | 2022-08-23 |
US20190374642A1 (en) | 2019-12-12 |
US20220072131A1 (en) | 2022-03-10 |
SG10201800166UA (en) | 2018-02-27 |
BR112016000338A8 (en) | 2020-01-07 |
JP2016529228A (en) | 2016-09-23 |
EP3019467A4 (en) | 2017-03-15 |
KR20160041912A (en) | 2016-04-18 |
CN105473545A (en) | 2016-04-06 |
CA2917159A1 (en) | 2015-01-15 |
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