SG11201510701QA - Biomarkers for cognitive dysfunction diseases and method for detecting cognitive dysfunction disease using biomarkers - Google Patents
Biomarkers for cognitive dysfunction diseases and method for detecting cognitive dysfunction disease using biomarkersInfo
- Publication number
- SG11201510701QA SG11201510701QA SG11201510701QA SG11201510701QA SG11201510701QA SG 11201510701Q A SG11201510701Q A SG 11201510701QA SG 11201510701Q A SG11201510701Q A SG 11201510701QA SG 11201510701Q A SG11201510701Q A SG 11201510701QA SG 11201510701Q A SG11201510701Q A SG 11201510701QA
- Authority
- SG
- Singapore
- Prior art keywords
- biomarkers
- cognitive dysfunction
- detecting
- diseases
- disease
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
- G06F17/10—Complex mathematical operations
- G06F17/18—Complex mathematical operations for evaluating statistical data, e.g. average values, frequency distributions, probability functions, regression analysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/76—Assays involving albumins other than in routine use for blocking surfaces or for anchoring haptens during immunisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/775—Apolipopeptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Data Mining & Analysis (AREA)
- Biophysics (AREA)
- Theoretical Computer Science (AREA)
- Mathematical Analysis (AREA)
- Mathematical Physics (AREA)
- Pure & Applied Mathematics (AREA)
- Mathematical Optimization (AREA)
- Wood Science & Technology (AREA)
- Computational Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Computational Biology (AREA)
- Databases & Information Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP2013/067785 WO2014207888A1 (en) | 2013-06-28 | 2013-06-28 | Biomarkers for cognitive dysfunction diseases and method for detecting cognitive dysfunction disease using biomarkers |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201510701QA true SG11201510701QA (en) | 2016-01-28 |
Family
ID=52141287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201510701QA SG11201510701QA (en) | 2013-06-28 | 2013-06-28 | Biomarkers for cognitive dysfunction diseases and method for detecting cognitive dysfunction disease using biomarkers |
Country Status (9)
Country | Link |
---|---|
US (3) | US20160178642A1 (en) |
EP (1) | EP3015865B1 (en) |
JP (1) | JP6265507B2 (en) |
KR (1) | KR101850827B1 (en) |
CN (2) | CN111426848A (en) |
CA (1) | CA2916861A1 (en) |
PH (1) | PH12015502849B1 (en) |
SG (1) | SG11201510701QA (en) |
WO (1) | WO2014207888A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109791139A (en) * | 2016-08-09 | 2019-05-21 | 大塚制药株式会社 | Use the aided diagnosis method for the Alzheimer that urine biology marks |
CN106645755B (en) * | 2016-12-30 | 2018-09-25 | 深圳大学 | A kind of AD biomarkers and its detection method |
WO2019012671A1 (en) * | 2017-07-13 | 2019-01-17 | 株式会社Mcbi | Biomarker for cognitive impairment disorders and detection method for cognitive impairment disorders using said biomarker |
JPWO2019013341A1 (en) * | 2017-07-14 | 2020-07-09 | 株式会社Mcbi | Disease detection method |
JP2019020206A (en) * | 2017-07-14 | 2019-02-07 | 株式会社島津製作所 | Cognitive disorder biomarker quantification method using mass analysis and mass spectroscope |
JP7109441B2 (en) * | 2017-07-25 | 2022-07-29 | 亨 長谷川 | Diagnostic aid method for determining neurodegenerative disease |
CN107389956B (en) * | 2017-08-31 | 2019-05-07 | 北京臻惠康生物科技有限公司 | New application and its kit of the transthyretin as TBI patient injury's Severity |
JP7434678B2 (en) * | 2019-05-20 | 2024-02-21 | 花王株式会社 | Testing methods for dementia or its risk |
JP7471834B2 (en) * | 2020-01-24 | 2024-04-22 | シスメックス株式会社 | Method for obtaining information regarding cognitive function, method for determining effectiveness of medical intervention regarding cognitive function, method for assisting in the determination of cognitive function, reagent kit, determination device, and computer program |
WO2022102654A1 (en) * | 2020-11-10 | 2022-05-19 | 株式会社Mcbi | Combination of biomarkers, and method for detecting cognitive dysfunction or risk thereof by using said combination |
WO2022125415A1 (en) * | 2020-12-07 | 2022-06-16 | President And Fellows Of Harvard College | Scg2 neuropeptides and uses thereof |
WO2022145074A1 (en) | 2020-12-28 | 2022-07-07 | 株式会社Mcbi | Judgment supporting information generating method, judgment supporting information generating system, and information processing device |
CN113684272A (en) * | 2021-09-08 | 2021-11-23 | 百世诺(北京)医学检验实验室有限公司 | Myocardial amyloidosis detection kit based on mutated TTR gene |
WO2024004944A1 (en) * | 2022-06-28 | 2024-01-04 | 株式会社Mcbi | Assessment-supporting information generating method, assessment-supporting information generating system, and information processing device |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004058052A2 (en) * | 2002-12-20 | 2004-07-15 | Applera Corporation | Genetic polymorphisms associated with myocardial infarction, methods of detection and uses thereof |
JP4170139B2 (en) | 2003-05-07 | 2008-10-22 | 財団法人癌研究会 | Method for detecting change in serum apolipoprotein A-II amount |
JP4801930B2 (en) | 2005-05-02 | 2011-10-26 | 株式会社Mcbi | Novel liver cancer biomarker and method for detecting liver cancer using the biomarker |
GB2428240A (en) * | 2005-07-14 | 2007-01-24 | Univ Gen Ve | Diagnostic method for brain damage-related disorders |
US7851172B2 (en) * | 2006-07-25 | 2010-12-14 | University Of Kentucky Research Foundation | Biomarkers of mild cognitive impairment and alzheimer's disease |
JP2010271078A (en) | 2009-05-19 | 2010-12-02 | Mcbi:Kk | Biomarker of mental disorder containing cognitive disorder, and method of detecting mental disorder containing cognitive disorder using biomarker |
JP2012037349A (en) | 2010-08-06 | 2012-02-23 | Mcbi:Kk | Biomarker of cognitive function disorder disease and method for detecting cognitive function disorder disease using the biomarker |
JP6012923B2 (en) * | 2010-12-22 | 2016-10-25 | 株式会社Mcbi | Biomarker for cognitive dysfunction disease and method for detecting cognitive dysfunction disease using the biomarker |
WO2012149607A1 (en) * | 2011-05-03 | 2012-11-08 | Commonwealth Scientific And Industrial Research Organisation | Method for detection of a neurological disease |
FI20115576A0 (en) * | 2011-06-10 | 2011-06-10 | Teknologian Tutkimuskeskus Vtt Oy | A method for diagnosing Alzheimer's disease |
-
2013
- 2013-06-28 EP EP13888380.6A patent/EP3015865B1/en active Active
- 2013-06-28 CN CN202010279332.3A patent/CN111426848A/en active Pending
- 2013-06-28 WO PCT/JP2013/067785 patent/WO2014207888A1/en active Application Filing
- 2013-06-28 KR KR1020167002424A patent/KR101850827B1/en active IP Right Grant
- 2013-06-28 SG SG11201510701QA patent/SG11201510701QA/en unknown
- 2013-06-28 CN CN201380078481.1A patent/CN105659093A/en active Pending
- 2013-06-28 US US14/901,275 patent/US20160178642A1/en not_active Abandoned
- 2013-06-28 CA CA2916861A patent/CA2916861A1/en not_active Abandoned
- 2013-06-28 JP JP2015523773A patent/JP6265507B2/en active Active
-
2015
- 2015-12-22 PH PH12015502849A patent/PH12015502849B1/en unknown
-
2020
- 2020-06-02 US US16/890,739 patent/US20200309789A1/en not_active Abandoned
-
2023
- 2023-07-12 US US18/221,053 patent/US20240003913A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20200309789A1 (en) | 2020-10-01 |
CA2916861A1 (en) | 2014-12-31 |
KR101850827B1 (en) | 2018-05-31 |
PH12015502849A1 (en) | 2016-03-21 |
JPWO2014207888A1 (en) | 2017-02-23 |
EP3015865A4 (en) | 2017-06-07 |
EP3015865A1 (en) | 2016-05-04 |
JP6265507B2 (en) | 2018-01-24 |
CN111426848A (en) | 2020-07-17 |
CN105659093A (en) | 2016-06-08 |
PH12015502849B1 (en) | 2016-03-21 |
EP3015865B1 (en) | 2020-03-25 |
WO2014207888A1 (en) | 2014-12-31 |
US20240003913A1 (en) | 2024-01-04 |
US20160178642A1 (en) | 2016-06-23 |
KR20160055780A (en) | 2016-05-18 |
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