SG11201510342VA - Improved process for production of monoclonal antibodies - Google Patents

Improved process for production of monoclonal antibodies

Info

Publication number
SG11201510342VA
SG11201510342VA SG11201510342VA SG11201510342VA SG11201510342VA SG 11201510342V A SG11201510342V A SG 11201510342VA SG 11201510342V A SG11201510342V A SG 11201510342VA SG 11201510342V A SG11201510342V A SG 11201510342VA SG 11201510342V A SG11201510342V A SG 11201510342VA
Authority
SG
Singapore
Prior art keywords
production
monoclonal antibodies
improved process
improved
monoclonal
Prior art date
Application number
SG11201510342VA
Inventor
Sanjeev Kumar Mendiratta
Sanjay Bandyopadhyay
Sanjay Patel
Original Assignee
Cadila Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Healthcare Ltd filed Critical Cadila Healthcare Ltd
Publication of SG11201510342VA publication Critical patent/SG11201510342VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
SG11201510342VA 2013-07-06 2014-07-07 Improved process for production of monoclonal antibodies SG11201510342VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2285MU2013 IN2013MU02285A (en) 2013-07-06 2014-07-07
PCT/IN2014/000450 WO2015004679A1 (en) 2013-07-06 2014-07-07 Improved process for production of monoclonal antibodies

Publications (1)

Publication Number Publication Date
SG11201510342VA true SG11201510342VA (en) 2016-01-28

Family

ID=51794933

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201510342VA SG11201510342VA (en) 2013-07-06 2014-07-07 Improved process for production of monoclonal antibodies

Country Status (18)

Country Link
US (1) US20160215319A1 (en)
EP (1) EP3019528A1 (en)
JP (1) JP2016526385A (en)
CN (1) CN105431454A (en)
AR (1) AR096839A1 (en)
AU (1) AU2014288811B2 (en)
BR (1) BR112015032800A2 (en)
CA (1) CA2917484A1 (en)
EA (1) EA201690171A1 (en)
HK (1) HK1218297A1 (en)
IL (1) IL243011A0 (en)
IN (1) IN2013MU02285A (en)
MX (1) MX2016000123A (en)
NZ (1) NZ715246A (en)
SG (1) SG11201510342VA (en)
TW (1) TW201514305A (en)
WO (1) WO2015004679A1 (en)
ZA (1) ZA201509334B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012149197A2 (en) 2011-04-27 2012-11-01 Abbott Laboratories Methods for controlling the galactosylation profile of recombinantly-expressed proteins
US9067990B2 (en) * 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
WO2013158279A1 (en) * 2012-04-20 2013-10-24 Abbvie Inc. Protein purification methods to reduce acidic species
WO2013176754A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Novel purification of antibodies using hydrophobic interaction chromatography
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
EP2830651A4 (en) 2013-03-12 2015-09-02 Abbvie Inc Human antibodies that bind human tnf-alpha and methods of preparing the same
US10023608B1 (en) 2013-03-13 2018-07-17 Amgen Inc. Protein purification methods to remove impurities
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
WO2015051293A2 (en) 2013-10-04 2015-04-09 Abbvie, Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
WO2017122157A1 (en) * 2016-01-14 2017-07-20 Dr. Reddy’S Laboratories Limited Cell culture process
JP2020188737A (en) * 2019-05-23 2020-11-26 東ソー株式会社 Production method of antibody with improved antibody dependent cell mediated cytotoxicity activity

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705364A (en) 1995-06-06 1998-01-06 Genentech, Inc. Mammalian cell culture process
JP4306813B2 (en) 1995-09-19 2009-08-05 アスビオファーマ株式会社 New method for culturing animal cells
JP2005509403A (en) * 2001-03-27 2005-04-14 スミスクライン・ビーチャム・コーポレイション Control of glycoforms in IgG
US7294484B2 (en) * 2004-08-27 2007-11-13 Wyeth Research Ireland Limited Production of polypeptides
RU2639288C2 (en) * 2009-08-11 2017-12-20 Дженентек, Инк. Proteins production in cultural media without glutamine
ES2776980T3 (en) * 2009-12-23 2020-08-03 Merck Sharp & Dohme 3M cell line
US20130210075A1 (en) * 2010-01-07 2013-08-15 Dr. Reddy's Laboratories, Inc. Enhanced protein expression
PT2563906T (en) * 2010-04-26 2018-02-16 Novartis Ag Process for cultivation of cho cells
US20130295613A1 (en) * 2010-12-28 2013-11-07 Chugai Seiyaku Kabushiki Kaisha Animal cell culturing method
SG11201504249XA (en) 2012-09-02 2015-07-30 Abbvie Inc Methods to control protein heterogeneity

Also Published As

Publication number Publication date
MX2016000123A (en) 2016-07-14
CN105431454A (en) 2016-03-23
BR112015032800A2 (en) 2017-07-25
US20160215319A1 (en) 2016-07-28
AR096839A1 (en) 2016-02-03
HK1218297A1 (en) 2017-02-10
JP2016526385A (en) 2016-09-05
CA2917484A1 (en) 2015-01-15
EP3019528A1 (en) 2016-05-18
EA201690171A1 (en) 2016-06-30
AU2014288811B2 (en) 2017-06-08
WO2015004679A1 (en) 2015-01-15
AU2014288811A1 (en) 2016-01-28
NZ715246A (en) 2017-07-28
IL243011A0 (en) 2016-03-31
IN2013MU02285A (en) 2015-06-19
TW201514305A (en) 2015-04-16
ZA201509334B (en) 2017-03-29

Similar Documents

Publication Publication Date Title
HK1218297A1 (en) Improved process for production of monoclonal antibodies
HK1217344A1 (en) Purification process for monoclonal antibodies
ZA201603433B (en) Production of t cell retargeting hetero-dimeric immunoglobulins
IL242408B (en) Continuous multistep process for purifying antibodies
PL3006568T3 (en) Production method for tagatose
IL242695B (en) Apparatus for production of molybdenum-99
ZA201506568B (en) Anti-tnf-anti-il-17 bispecific antibodies
HK1223953A1 (en) Humanized anti-tau(ps422) antibodies and methods of use -tau(ps422)
EP3663287C0 (en) Process scale synthesis of urolithins
EP2995679A4 (en) METHOD FOR PRODUCING MONOCLONAL IgA ANTIBODY
PL3074360T3 (en) Process for manufacture of portland cement
SI3027634T1 (en) Process for preparation of tulathromycin
IL239737A0 (en) Method of producing a protein
IL239689A0 (en) Method for producing antibodies
IL245474B (en) Process for the preparation of 5-fluoro-1h-pyrazoles
IL245476B (en) Process for the preparation of 5-fluoro-1h-pyrazoles
EP2952895A4 (en) Method of producing labeled antibody
SG11201507727VA (en) Process for the manufacture of polypropylene
IL241779A0 (en) Method for producing protein
IL229326A (en) Process for the preparation of n-iodoamides
PL3087039T3 (en) Process for the manufacture of glass elements
ZA201603839B (en) Process for the production of synthesis gas
HK1215714A1 (en) Anti-() --methamphetamine monoclonal antibodies ()-
PT2799426T (en) New process for the synthesis of aminaphtone
GB201301319D0 (en) Process for the production of abalone probiotics