SG11201508338VA - Antimicrobial cationic polycarbonates - Google Patents
Antimicrobial cationic polycarbonatesInfo
- Publication number
- SG11201508338VA SG11201508338VA SG11201508338VA SG11201508338VA SG11201508338VA SG 11201508338V A SG11201508338V A SG 11201508338VA SG 11201508338V A SG11201508338V A SG 11201508338VA SG 11201508338V A SG11201508338V A SG 11201508338VA SG 11201508338V A SG11201508338V A SG 11201508338VA
- Authority
- SG
- Singapore
- Prior art keywords
- antimicrobial cationic
- polycarbonates
- cationic polycarbonates
- antimicrobial
- cationic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/64—Polyesters containing both carboxylic ester groups and carbonate groups
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/34—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-halogen bonds; Phosphonium salts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
- C08G64/02—Aliphatic polycarbonates
- C08G64/0208—Aliphatic polycarbonates saturated
- C08G64/0225—Aliphatic polycarbonates saturated containing atoms other than carbon, hydrogen or oxygen
- C08G64/0233—Aliphatic polycarbonates saturated containing atoms other than carbon, hydrogen or oxygen containing halogens
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
- C08G64/02—Aliphatic polycarbonates
- C08G64/0208—Aliphatic polycarbonates saturated
- C08G64/0225—Aliphatic polycarbonates saturated containing atoms other than carbon, hydrogen or oxygen
- C08G64/0241—Aliphatic polycarbonates saturated containing atoms other than carbon, hydrogen or oxygen containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
- C08G64/02—Aliphatic polycarbonates
- C08G64/0208—Aliphatic polycarbonates saturated
- C08G64/0225—Aliphatic polycarbonates saturated containing atoms other than carbon, hydrogen or oxygen
- C08G64/025—Aliphatic polycarbonates saturated containing atoms other than carbon, hydrogen or oxygen containing sulfur
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
- C08G64/02—Aliphatic polycarbonates
- C08G64/0208—Aliphatic polycarbonates saturated
- C08G64/0225—Aliphatic polycarbonates saturated containing atoms other than carbon, hydrogen or oxygen
- C08G64/0258—Aliphatic polycarbonates saturated containing atoms other than carbon, hydrogen or oxygen containing phosphorus
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
- C08G64/02—Aliphatic polycarbonates
- C08G64/0291—Aliphatic polycarbonates unsaturated
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
- C08G64/20—General preparatory processes
- C08G64/30—General preparatory processes using carbonates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
- C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/54—Polymers characterized by specific structures/properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/54—Polymers characterized by specific structures/properties
- A61K2800/542—Polymers characterized by specific structures/properties characterized by the charge
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/54—Polymers characterized by specific structures/properties
- A61K2800/542—Polymers characterized by specific structures/properties characterized by the charge
- A61K2800/5426—Polymers characterized by specific structures/properties characterized by the charge cationic
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polyesters Or Polycarbonates (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/859,048 US9357772B2 (en) | 2013-04-09 | 2013-04-09 | Antimicrobial cationic polycarbonates |
PCT/US2014/031982 WO2014168762A1 (en) | 2013-04-09 | 2014-03-27 | Antimicrobial cationic polycarbonates |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201508338VA true SG11201508338VA (en) | 2015-11-27 |
Family
ID=51654606
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201508338VA SG11201508338VA (en) | 2013-04-09 | 2014-03-27 | Antimicrobial cationic polycarbonates |
Country Status (8)
Country | Link |
---|---|
US (2) | US9357772B2 (en) |
EP (1) | EP2983692A4 (en) |
JP (2) | JP6391671B2 (en) |
CN (1) | CN105101988B (en) |
DE (1) | DE112014001240T5 (en) |
GB (1) | GB2526953A (en) |
SG (1) | SG11201508338VA (en) |
WO (1) | WO2014168762A1 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9357772B2 (en) | 2013-04-09 | 2016-06-07 | International Business Machines Corporation | Antimicrobial cationic polycarbonates |
US9999633B2 (en) * | 2013-04-09 | 2018-06-19 | International Business Machines Corporation | Antimicrobial cationic polycarbonates |
WO2016060616A1 (en) * | 2014-10-14 | 2016-04-21 | Agency For Science, Technology And Research | Antibacterial and/or antifouling polymers |
US9580554B2 (en) * | 2015-05-06 | 2017-02-28 | International Business Machines Corporation | Condensation polymers for antimicrobial applications |
US9854806B2 (en) * | 2015-05-19 | 2018-01-02 | International Business Machines Corporation | Antimicrobial guanidinium and thiouronium functionalized polymers |
WO2017078622A1 (en) * | 2015-11-04 | 2017-05-11 | Agency For Science, Technology And Research | Antibacterial particles functionalized with polyalkylene imine and its derivatives for water disinfection |
US10774191B2 (en) * | 2017-08-08 | 2020-09-15 | Gentex Corporation | Electro-optical device having a transparent ion exchange membrane |
US10463746B2 (en) * | 2017-11-09 | 2019-11-05 | International Business Machines Corporation | Macromolecular chemotherapeutics |
US10561146B2 (en) | 2017-11-28 | 2020-02-18 | International Business Machines Corporation | Star polymers with enhanced antimicrobial activity in response to light |
US10953039B2 (en) | 2018-09-27 | 2021-03-23 | International Business Machines Corporation | Utilizing polymers and antibiotics to enhance antimicrobial activity and inhibit antibiotic resistance |
US11167036B2 (en) * | 2018-11-27 | 2021-11-09 | International Business Machines Corporation | Techniques for enhancing the selectivity and efficacy of antimicrobial and anticancer polymer agents |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004043330A2 (en) | 2002-11-07 | 2004-05-27 | L'oreal | Cosmetic composition comprising at least one specific cyclic carbonate which may be polymerised |
US20040115160A1 (en) | 2002-12-13 | 2004-06-17 | Salamone Joseph C. | Quaternary ammonium esters for disinfection and preservation |
WO2007061954A2 (en) * | 2005-11-18 | 2007-05-31 | University Of Pittsburgh | Biocidal surfaces, articles with biocidal surface agents and methods of synthesizing and evaluating biocidal surface agents |
CA2652078A1 (en) | 2006-05-15 | 2007-11-22 | Tyco Healthcare Group Lp | Halogenated cyclic lactones and polymers made therefrom |
GB2447478A (en) | 2007-03-14 | 2008-09-17 | Reckitt Benckiser Inc | Aqueous topical compositions with antimicrobial benefit |
FR2915748B1 (en) | 2007-05-03 | 2012-10-19 | Flamel Tech Sa | POLYGLUTAMIC ACIDS FUNCTIONALIZED BY CATIONIC GROUPS AND HYDROPHOBIC GROUPS AND THEIR APPLICATIONS, IN PARTICULAR THERAPEUTIC |
GB0713799D0 (en) | 2007-07-17 | 2007-08-22 | Byotrol Llc | Anti-microbial compositions |
US8153618B2 (en) | 2007-08-10 | 2012-04-10 | Allaccem, Inc. | Bridged polycyclic compound based compositions for topical applications for pets |
WO2009078820A1 (en) | 2007-12-18 | 2009-06-25 | Agency For Science, Technology And Research | Cationic core-shell peptide nanoparticles |
CN101951779A (en) | 2007-12-31 | 2011-01-19 | 3M创新有限公司 | Antimicrobial compositions |
EP2440540A4 (en) | 2009-06-08 | 2012-12-12 | Univ Massachusetts | Antimicrobial polymers |
US8263715B2 (en) | 2009-08-28 | 2012-09-11 | International Business Machines Corporation | Hydrogel compositions and methods of preparation thereof |
US20110151566A1 (en) * | 2009-12-23 | 2011-06-23 | James Hedrick | Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto |
US8361495B2 (en) | 2009-12-23 | 2013-01-29 | International Business Machines Corporation | Antimicrobial polymers and methods of manufacture thereof |
US8226985B2 (en) | 2010-01-28 | 2012-07-24 | International Business Machines Corporation | Surface modified nanoparticles, methods of their preparation, and uses thereof for gene and drug delivery |
EP2646048B1 (en) | 2010-11-30 | 2017-11-01 | The Board of Trustees of the University of Illionis | Stable helical ionic polypeptides |
US8834861B2 (en) | 2011-03-10 | 2014-09-16 | International Business Machines Corporation | Polycarbonates for delivery of drugs and methods of preparation thereof |
US8709466B2 (en) | 2011-03-31 | 2014-04-29 | International Business Machines Corporation | Cationic polymers for antimicrobial applications and delivery of bioactive materials |
US8642086B2 (en) | 2011-03-31 | 2014-02-04 | International Business Machines Corporation | Antimicrobial compositions, methods of preparation thereof, and uses thereof |
US9902957B2 (en) * | 2011-09-06 | 2018-02-27 | The Board Of Trustees Of The Leland Stanford Junior University | Amphipathic co-oligomers for the delivery of siRNA |
US8926998B2 (en) | 2012-09-12 | 2015-01-06 | International Business Machines Corporation | Polycarbonates bearing pendant primary amines for medical applications |
US9999633B2 (en) | 2013-04-09 | 2018-06-19 | International Business Machines Corporation | Antimicrobial cationic polycarbonates |
US9357772B2 (en) | 2013-04-09 | 2016-06-07 | International Business Machines Corporation | Antimicrobial cationic polycarbonates |
-
2013
- 2013-04-09 US US13/859,048 patent/US9357772B2/en not_active Expired - Fee Related
-
2014
- 2014-03-27 CN CN201480020494.8A patent/CN105101988B/en active Active
- 2014-03-27 DE DE112014001240.8T patent/DE112014001240T5/en not_active Withdrawn
- 2014-03-27 WO PCT/US2014/031982 patent/WO2014168762A1/en active Application Filing
- 2014-03-27 EP EP14782368.6A patent/EP2983692A4/en not_active Withdrawn
- 2014-03-27 SG SG11201508338VA patent/SG11201508338VA/en unknown
- 2014-03-27 JP JP2016507551A patent/JP6391671B2/en active Active
- 2014-03-27 GB GB1513172.5A patent/GB2526953A/en not_active Withdrawn
-
2016
- 2016-05-14 US US15/154,948 patent/US9631050B2/en not_active Expired - Fee Related
-
2017
- 2017-12-01 JP JP2017231861A patent/JP6474880B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US9631050B2 (en) | 2017-04-25 |
CN105101988B (en) | 2017-04-05 |
DE112014001240T5 (en) | 2016-01-21 |
JP6474880B2 (en) | 2019-02-27 |
US20160257782A1 (en) | 2016-09-08 |
US20140301968A1 (en) | 2014-10-09 |
JP6391671B2 (en) | 2018-09-19 |
GB2526953A (en) | 2015-12-09 |
EP2983692A4 (en) | 2017-05-17 |
EP2983692A1 (en) | 2016-02-17 |
WO2014168762A1 (en) | 2014-10-16 |
JP2016522274A (en) | 2016-07-28 |
US9357772B2 (en) | 2016-06-07 |
CN105101988A (en) | 2015-11-25 |
GB201513172D0 (en) | 2015-09-09 |
JP2018066014A (en) | 2018-04-26 |
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