SG11201508111QA - Modified g-quadruplex nanoparticles - Google Patents
Modified g-quadruplex nanoparticlesInfo
- Publication number
- SG11201508111QA SG11201508111QA SG11201508111QA SG11201508111QA SG11201508111QA SG 11201508111Q A SG11201508111Q A SG 11201508111QA SG 11201508111Q A SG11201508111Q A SG 11201508111QA SG 11201508111Q A SG11201508111Q A SG 11201508111QA SG 11201508111Q A SG11201508111Q A SG 11201508111QA
- Authority
- SG
- Singapore
- Prior art keywords
- quadruplex
- nanoparticles
- modified
- quadruplex nanoparticles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361816354P | 2013-04-26 | 2013-04-26 | |
| PCT/SG2014/000189 WO2014175836A1 (en) | 2013-04-26 | 2014-04-28 | Modified g-quadruplex nanoparticles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201508111QA true SG11201508111QA (en) | 2015-10-29 |
Family
ID=51792236
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201508111QA SG11201508111QA (en) | 2013-04-26 | 2014-04-28 | Modified g-quadruplex nanoparticles |
| SG10201708712SA SG10201708712SA (en) | 2013-04-26 | 2014-04-28 | Modified g-quadruplex nanoparticles |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201708712SA SG10201708712SA (en) | 2013-04-26 | 2014-04-28 | Modified g-quadruplex nanoparticles |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20160310519A1 (en) |
| EP (1) | EP2989112B1 (en) |
| SG (2) | SG11201508111QA (en) |
| WO (1) | WO2014175836A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10568898B2 (en) | 2013-08-13 | 2020-02-25 | Northwestern University | Lipophilic nanoparticles for drug delivery |
| AU2015240567A1 (en) * | 2014-04-03 | 2016-10-20 | Exicure, Inc. | Self assembling nucleic acid nanostructures |
| JP2017537619A (en) | 2014-11-21 | 2017-12-21 | ノースウェスタン ユニバーシティ | Sequence-specific intracellular uptake of spherical nucleic acid nanoparticle complexes |
| CN108064295A (en) | 2015-01-14 | 2018-05-22 | 埃克西奎雷股份有限公司 | Nucleic acid nano structure with core motif |
| SG11201809002RA (en) | 2016-04-29 | 2018-11-29 | Univ Nanyang Tech | G-quadruplex-containing antisense oligonucleotides |
| US11364304B2 (en) | 2016-08-25 | 2022-06-21 | Northwestern University | Crosslinked micellar spherical nucleic acids |
| CA2954115C (en) * | 2016-10-16 | 2022-04-12 | Neil Gordon | Ultra-sensitive bioanalyte quantification from self-assembled quadruplex tags |
| US11696954B2 (en) | 2017-04-28 | 2023-07-11 | Exicure Operating Company | Synthesis of spherical nucleic acids using lipophilic moieties |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006302022A1 (en) | 2005-10-06 | 2007-04-19 | University Of Delaware | G-rich polynucleotides for the treatment of Huntington's Disease |
| US20080096838A1 (en) | 2006-08-08 | 2008-04-24 | Kmiec Eric B | Guanosine rich oligonucleotides and methods of inducing apoptosis in tumor cells |
| CN101942000A (en) * | 2010-04-13 | 2011-01-12 | 深圳华因康基因科技有限公司 | Nucleotide carrying modifiers and preparation method thereof and method for gene sequencing |
-
2014
- 2014-04-28 EP EP14788130.4A patent/EP2989112B1/en active Active
- 2014-04-28 SG SG11201508111QA patent/SG11201508111QA/en unknown
- 2014-04-28 WO PCT/SG2014/000189 patent/WO2014175836A1/en active Application Filing
- 2014-04-28 SG SG10201708712SA patent/SG10201708712SA/en unknown
- 2014-04-28 US US14/787,166 patent/US20160310519A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20160310519A1 (en) | 2016-10-27 |
| EP2989112A4 (en) | 2017-01-25 |
| SG10201708712SA (en) | 2017-12-28 |
| WO2014175836A1 (en) | 2014-10-30 |
| EP2989112B1 (en) | 2021-09-22 |
| EP2989112A1 (en) | 2016-03-02 |
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