SG11201507875RA - Protein production method - Google Patents
Protein production methodInfo
- Publication number
- SG11201507875RA SG11201507875RA SG11201507875RA SG11201507875RA SG11201507875RA SG 11201507875R A SG11201507875R A SG 11201507875RA SG 11201507875R A SG11201507875R A SG 11201507875RA SG 11201507875R A SG11201507875R A SG 11201507875RA SG 11201507875R A SG11201507875R A SG 11201507875RA
- Authority
- SG
- Singapore
- Prior art keywords
- production method
- protein production
- protein
- production
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000014616 translation Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/34—Sugars
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/46—Amines, e.g. putrescine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/76—Undefined extracts from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2523/00—Culture process characterised by temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361805215P | 2013-03-26 | 2013-03-26 | |
US201461933665P | 2014-01-30 | 2014-01-30 | |
PCT/US2014/031883 WO2014160790A1 (en) | 2013-03-26 | 2014-03-26 | Protein production method |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201507875RA true SG11201507875RA (en) | 2015-10-29 |
Family
ID=51621470
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201507875RA SG11201507875RA (en) | 2013-03-26 | 2014-03-26 | Protein production method |
SG10201802023RA SG10201802023RA (en) | 2013-03-26 | 2014-03-26 | Protein production method |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201802023RA SG10201802023RA (en) | 2013-03-26 | 2014-03-26 | Protein production method |
Country Status (12)
Country | Link |
---|---|
US (2) | US9765139B2 (en) |
EP (2) | EP3391942A1 (en) |
JP (2) | JP6689189B2 (en) |
KR (1) | KR20150133833A (en) |
AU (2) | AU2014241259B9 (en) |
BR (1) | BR112015024755A2 (en) |
CA (1) | CA2907771C (en) |
HK (1) | HK1218893A1 (en) |
MX (2) | MX362922B (en) |
RS (1) | RS59328B1 (en) |
SG (2) | SG11201507875RA (en) |
WO (1) | WO2014160790A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010138263A2 (en) | 2009-05-28 | 2010-12-02 | University Of Massachusetts | Novel aav 's and uses thereof |
CN107073051B (en) | 2014-10-21 | 2021-08-24 | 马萨诸塞大学 | Recombinant AAV variants and uses thereof |
KR101936049B1 (en) | 2015-10-15 | 2019-01-08 | (주)알테오젠 | Method for manufacturing fusion proteins with IgG Fc domain |
US11578340B2 (en) | 2016-10-13 | 2023-02-14 | University Of Massachusetts | AAV capsid designs |
MA50911A (en) * | 2017-11-13 | 2020-09-23 | Amgen Inc | PROTEIN PRODUCTS PRODUCTION PROCESSES |
CN109971705A (en) * | 2019-04-16 | 2019-07-05 | 上海汉尼生物细胞技术有限公司 | A kind of CHO DG44 cell culture medium additive and preparation method thereof |
JP2024503239A (en) * | 2020-12-22 | 2024-01-25 | アムジェン インコーポレイテッド | Cell culture method |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2817235A (en) | 1954-03-22 | 1957-12-24 | Phillips Petroleum Co | Temperature measuring system for underground storage cavern |
US2893211A (en) | 1955-05-16 | 1959-07-07 | Phillips Petroleum Co | Underground storage system |
US3064436A (en) | 1955-10-27 | 1962-11-20 | Robert L Loofbourow | Sealing underground cavities |
DE1126800B (en) | 1958-03-17 | 1962-03-29 | Stamicarbon | Device for conveying coarse-grained goods, such as ore and coal, from great depths, e.g. from a colliery or the like, by means of a transport fluid |
US3068654A (en) | 1958-09-22 | 1962-12-18 | Interstate Service Corp | Underground storage cavern and method of making same |
US3184922A (en) | 1960-07-12 | 1965-05-25 | Suburban Propane Gas Corp | Method of and means for storing liquefied petroleum gases underground |
US4011736A (en) | 1975-11-12 | 1977-03-15 | Halm Instrument Co., Inc. | Cold storage tank |
FR2372751A1 (en) | 1976-12-02 | 1978-06-30 | Commissariat Energie Atomique | UNDERGROUND TANK FOR PRESSURIZED FLUIDS |
SE450509B (en) | 1981-08-07 | 1987-06-29 | Karl Ivar Sagefors | METHOD OF BUILDING A PLANT FOR STORAGE OF LIQUID PRODUCTS IN BERG |
WO1983004455A1 (en) | 1982-06-09 | 1983-12-22 | John Canevall | Procedure for permanently storing radioactive material |
US4488834A (en) | 1982-11-17 | 1984-12-18 | Empak, Inc. | Method for using salt deposits for storage |
FR2545067B1 (en) | 1983-04-26 | 1987-08-07 | Geostock | PROCESS AND DEVICE FOR UNDERGROUND STORAGE OF AMMONIA AND THE LIKE |
US5207530A (en) | 1992-07-29 | 1993-05-04 | Halliburton Company | Underground compressed natural gas storage and service system |
US7294481B1 (en) * | 1999-01-05 | 2007-11-13 | Immunex Corporation | Method for producing recombinant proteins |
US6261805B1 (en) | 1999-07-15 | 2001-07-17 | Boyce Thompson Institute For Plant Research, Inc. | Sialyiation of N-linked glycoproteins in the baculovirus expression vector system |
US6826911B2 (en) | 2001-03-12 | 2004-12-07 | Pomfret Storage Company, Llc | Storage of energy producing fluids and process thereof |
MXPA05000552A (en) | 2002-07-15 | 2005-04-28 | Immunex Corp | Methods and media for controlling sialylation of proteins produced by mammalian cells. |
DK1720972T3 (en) * | 2004-03-05 | 2014-04-14 | Dsm Ip Assets Bv | METHOD OF CELL CULTIVATION USING CONTINUOUS PERFUSION AND ALTERNATIVE TANGENTIAL FLOW |
US7300773B2 (en) | 2004-08-27 | 2007-11-27 | Wyeth Research Ireland Limited | Production of TNFR-Ig |
DK1885753T3 (en) * | 2005-06-03 | 2011-10-03 | Ares Trading Sa | Preparation of Recombinant II-18 Proteins |
SI1957630T2 (en) * | 2005-12-08 | 2023-07-31 | Amgen Inc. | Improved production of glycoproteins using manganese |
EP2115126B1 (en) * | 2007-03-02 | 2015-04-08 | Wyeth LLC | Use of copper and glutamate in cell culture for production of polypeptides |
TW200902708A (en) | 2007-04-23 | 2009-01-16 | Wyeth Corp | Methods of protein production using anti-senescence compounds |
EP2014760A1 (en) * | 2007-06-13 | 2009-01-14 | CMC Biopharmaceuticals A/S | A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process |
US20120329709A1 (en) * | 2009-05-26 | 2012-12-27 | Brian Edward Collins | Production of glycoproteins |
US9540426B2 (en) | 2009-10-06 | 2017-01-10 | Bristol-Myers Squibb Company | Mammalian cell culture processes for protein production |
WO2011116148A2 (en) | 2010-03-16 | 2011-09-22 | Dana Todd C | Systems, apparatus and methods for extraction of hydrocarbons from organic materials |
CN102382794B (en) * | 2010-09-01 | 2013-09-18 | 山东新时代药业有限公司 | Perfusion culture method of mammal cell |
EP2702077A2 (en) | 2011-04-27 | 2014-03-05 | AbbVie Inc. | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
CA2952347A1 (en) * | 2011-07-01 | 2013-01-10 | Amgen Inc. | Mammalian cell culture |
BR112014000352A2 (en) * | 2011-07-08 | 2017-02-14 | Merck Sharp & Dohe Corp | method of purifying a fc-fc protein, fc proteins containing purified fc, purified tnfr: fc, and highly purified tnfr: fc |
-
2014
- 2014-03-26 JP JP2016505549A patent/JP6689189B2/en not_active Expired - Fee Related
- 2014-03-26 SG SG11201507875RA patent/SG11201507875RA/en unknown
- 2014-03-26 MX MX2015013668A patent/MX362922B/en active IP Right Grant
- 2014-03-26 SG SG10201802023RA patent/SG10201802023RA/en unknown
- 2014-03-26 BR BR112015024755A patent/BR112015024755A2/en not_active Application Discontinuation
- 2014-03-26 WO PCT/US2014/031883 patent/WO2014160790A1/en active Application Filing
- 2014-03-26 RS RSP20191090 patent/RS59328B1/en unknown
- 2014-03-26 KR KR1020157030631A patent/KR20150133833A/en not_active Application Discontinuation
- 2014-03-26 EP EP18176880.5A patent/EP3391942A1/en not_active Withdrawn
- 2014-03-26 EP EP14776207.4A patent/EP2978498B1/en active Active
- 2014-03-26 AU AU2014241259A patent/AU2014241259B9/en not_active Ceased
- 2014-03-26 US US14/226,522 patent/US9765139B2/en active Active
- 2014-03-26 CA CA2907771A patent/CA2907771C/en active Active
-
2015
- 2015-06-30 US US14/788,250 patent/US10975138B2/en active Active
- 2015-09-25 MX MX2019002183A patent/MX2019002183A/en unknown
-
2016
- 2016-06-15 HK HK16106899.1A patent/HK1218893A1/en not_active IP Right Cessation
-
2019
- 2019-02-18 AU AU2019201129A patent/AU2019201129B2/en not_active Ceased
- 2019-12-19 JP JP2019229576A patent/JP2020073503A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2014160790A1 (en) | 2014-10-02 |
KR20150133833A (en) | 2015-11-30 |
MX2019002183A (en) | 2019-05-16 |
EP3391942A1 (en) | 2018-10-24 |
US9765139B2 (en) | 2017-09-19 |
MX2015013668A (en) | 2016-06-28 |
JP2020073503A (en) | 2020-05-14 |
RS59328B1 (en) | 2019-10-31 |
MX362922B (en) | 2019-02-25 |
AU2019201129B2 (en) | 2020-12-24 |
HK1218893A1 (en) | 2017-03-17 |
CA2907771C (en) | 2023-01-10 |
EP2978498A1 (en) | 2016-02-03 |
SG10201802023RA (en) | 2018-05-30 |
US20160122427A1 (en) | 2016-05-05 |
JP6689189B2 (en) | 2020-04-28 |
EP2978498B1 (en) | 2019-07-03 |
AU2014241259B2 (en) | 2018-12-06 |
EP2978498A4 (en) | 2016-10-05 |
AU2014241259A1 (en) | 2015-10-22 |
AU2014241259B9 (en) | 2018-12-20 |
CA2907771A1 (en) | 2014-10-02 |
AU2019201129A1 (en) | 2019-03-07 |
US20140296489A1 (en) | 2014-10-02 |
BR112015024755A2 (en) | 2017-07-18 |
JP2016514475A (en) | 2016-05-23 |
US10975138B2 (en) | 2021-04-13 |
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