SG11201507469RA - Processes for producing sovaprevir - Google Patents
Processes for producing sovaprevirInfo
- Publication number
- SG11201507469RA SG11201507469RA SG11201507469RA SG11201507469RA SG11201507469RA SG 11201507469R A SG11201507469R A SG 11201507469RA SG 11201507469R A SG11201507469R A SG 11201507469RA SG 11201507469R A SG11201507469R A SG 11201507469RA SG 11201507469R A SG11201507469R A SG 11201507469RA
- Authority
- SG
- Singapore
- Prior art keywords
- sovaprevir
- processes
- producing
- producing sovaprevir
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361784182P | 2013-03-14 | 2013-03-14 | |
| PCT/US2014/028278 WO2014152928A2 (en) | 2013-03-14 | 2014-03-14 | Novel processes for producing sovaprevir |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201507469RA true SG11201507469RA (en) | 2015-10-29 |
Family
ID=50680160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201507469RA SG11201507469RA (en) | 2013-03-14 | 2014-03-14 | Processes for producing sovaprevir |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9115175B2 (en) |
| EP (1) | EP2970195B1 (en) |
| JP (1) | JP2016515139A (en) |
| KR (1) | KR20160005334A (en) |
| CN (1) | CN105408317A (en) |
| AU (1) | AU2014236502A1 (en) |
| BR (1) | BR112015023343A2 (en) |
| CA (1) | CA2905433A1 (en) |
| EA (1) | EA201591722A1 (en) |
| IL (1) | IL241287A0 (en) |
| PH (1) | PH12015502121A1 (en) |
| SG (1) | SG11201507469RA (en) |
| WO (1) | WO2014152928A2 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2374812B1 (en) | 2006-07-13 | 2015-04-15 | Achillion Pharmaceuticals, Inc. | 4-amino-4-oxobutanoyl Peptides as Inhibitors of Viral Replication |
| CN109562107A (en) | 2016-05-10 | 2019-04-02 | C4医药公司 | Heterocycle degron body for target protein degradation |
| CN109562113A (en) | 2016-05-10 | 2019-04-02 | C4医药公司 | Loop coil degron body for target protein degradation |
| WO2017197046A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | C3-carbon linked glutarimide degronimers for target protein degradation |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6323180B1 (en) | 1998-08-10 | 2001-11-27 | Boehringer Ingelheim (Canada) Ltd | Hepatitis C inhibitor tri-peptides |
| US6608027B1 (en) | 1999-04-06 | 2003-08-19 | Boehringer Ingelheim (Canada) Ltd | Macrocyclic peptides active against the hepatitis C virus |
| HUP0500456A3 (en) * | 2000-11-20 | 2012-05-02 | Bristol Myers Squibb Co | Hepatitis c tripeptide inhibitors, pharmaceutical compositions comprising thereof and their use |
| MY140680A (en) | 2002-05-20 | 2010-01-15 | Bristol Myers Squibb Co | Hepatitis c virus inhibitors |
| US20060199773A1 (en) | 2002-05-20 | 2006-09-07 | Sausker Justin B | Crystalline forms of (1R,2S)-N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(6-methoxy-1-isoquinolinyl)oxy]-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-cyclopropanecarboxamide, monopotassium salt |
| ES2361011T3 (en) | 2002-05-20 | 2011-06-13 | Bristol-Myers Squibb Company | HEPATITIS VIRUS INHIBITORS C. |
| ES2350201T3 (en) | 2002-05-20 | 2011-01-20 | Bristol-Myers Squibb Company | HETEROCYCLIC SULPHAMIDES AS INHIBITORS OF HEPATITIS C VIRUS. |
| EP1505945B1 (en) | 2002-05-20 | 2008-11-05 | Bristol-Myers Squibb Company | Substituted cycloalkyl p1' hepatitis c virus inhibitors |
| CA2515216A1 (en) | 2003-02-07 | 2004-08-26 | Enanta Pharmaceuticals, Inc. | Macrocyclic hepatitis c serine protease inhibitors |
| DE602004029866D1 (en) | 2003-03-05 | 2010-12-16 | Boehringer Ingelheim Pharma | PEPTIDE ANALOGUE WITH INHIBITORAL EFFECT ON HEPATITIS C |
| EP1629000B1 (en) | 2003-04-16 | 2009-02-18 | Bristol-Myers Squibb Company | Macrocyclic isoquinoline peptide inhibitors of hepatitis c virus |
| US7176208B2 (en) | 2003-04-18 | 2007-02-13 | Enanta Pharmaceuticals, Inc. | Quinoxalinyl macrocyclic hepatitis C serine protease inhibitors |
| DE602004010137T2 (en) | 2003-05-21 | 2008-09-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | COMPOUNDS AS HEPATITIS C INHIBITORS |
| WO2004113365A2 (en) | 2003-06-05 | 2004-12-29 | Enanta Pharmaceuticals, Inc. | Hepatitis c serine protease tri-peptide inhibitors |
| CN102020700A (en) | 2003-07-18 | 2011-04-20 | 沃泰克斯药物股份有限公司 | Inhibitors of serine proteases, particularly hcv ns3-ns4a protease |
| PE20050431A1 (en) | 2003-09-22 | 2005-07-19 | Boehringer Ingelheim Int | MACROCYCLIC PEPTIDES ACTIVE AGAINST HEPATITIS C VIRUS |
| MXPA06003963A (en) | 2003-10-14 | 2006-08-25 | Intermune Inc | Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication. |
| US7132504B2 (en) | 2003-11-12 | 2006-11-07 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US7309708B2 (en) | 2003-11-20 | 2007-12-18 | Birstol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US7135462B2 (en) | 2003-11-20 | 2006-11-14 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| ES2358333T3 (en) | 2004-01-21 | 2011-05-09 | Boehringer Ingelheim International Gmbh | MACROCYCLIC PEPTIDES WITH ACTION AGAINST THE VIRUS OF HEPATITIS C. |
| JP4902361B2 (en) | 2004-01-30 | 2012-03-21 | メディヴィル・アクチエボラーグ | HCVNS-3 serine protease inhibitor |
| JP4654239B2 (en) | 2004-03-15 | 2011-03-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Method for preparing macrocyclic dipeptide suitable for treatment of hepatitis C virus infection |
| JP4950026B2 (en) | 2004-03-30 | 2012-06-13 | インターミューン・インコーポレーテッド | Macrocyclic compounds as viral replication inhibitors |
| UY29016A1 (en) | 2004-07-20 | 2006-02-24 | Boehringer Ingelheim Int | ANALOGS OF INHIBITING DIPEPTIDES OF HEPATITIS C |
| CA2573346C (en) | 2004-07-20 | 2011-09-20 | Boehringer Ingelheim International Gmbh | Hepatitis c inhibitor peptide analogs |
| EP1794178A1 (en) | 2004-09-17 | 2007-06-13 | Boehringer Ingelheim International Gmbh | Process for preparing macrocyclic hcv protease inhibitors |
| US7323447B2 (en) | 2005-02-08 | 2008-01-29 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| ES2439732T3 (en) | 2005-03-08 | 2014-01-24 | Boehringer Ingelheim International Gmbh | Procedure for preparing macrocyclic compounds |
| US7592336B2 (en) * | 2005-05-10 | 2009-09-22 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US7608592B2 (en) | 2005-06-30 | 2009-10-27 | Virobay, Inc. | HCV inhibitors |
| US7601686B2 (en) | 2005-07-11 | 2009-10-13 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| TWI389908B (en) | 2005-07-14 | 2013-03-21 | Gilead Sciences Inc | Antiviral compounds |
| JP2009501732A (en) | 2005-07-20 | 2009-01-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Hepatitis C inhibitor peptide analog |
| MX2008001166A (en) | 2005-07-25 | 2008-03-18 | Intermune Inc | Novel macrocyclic inhibitors of hepatitis c virus replication. |
| JO2768B1 (en) | 2005-07-29 | 2014-03-15 | تيبوتيك فارماسيوتيكالز ليمتد | Macrocylic Inhibitors Hepatitis C Virus |
| ES2364426T3 (en) | 2005-09-09 | 2011-09-02 | Boehringer Ingelheim International Gmbh | METAL PROCESS WITH CLOSURE OF THE RING FOR THE PREPARATION OF MACROCYCLIC PEPTIDES. |
| ES2356776T3 (en) | 2005-10-11 | 2011-04-13 | Intermune, Inc. | COMPOUNDS AND METHODS TO INHIBIT THE REPLICATION OF THE HEPATITIS VIRUS. |
| US7772183B2 (en) | 2005-10-12 | 2010-08-10 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US7741281B2 (en) | 2005-11-03 | 2010-06-22 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| SI2041156T1 (en) * | 2006-07-13 | 2014-04-30 | Achillion Pharmacetuticals, Inc. | 4-amino-4-oxobutanoyl peptides as inhibitors of viral replication |
| EP2374812B1 (en) | 2006-07-13 | 2015-04-15 | Achillion Pharmaceuticals, Inc. | 4-amino-4-oxobutanoyl Peptides as Inhibitors of Viral Replication |
| PT2364309E (en) | 2008-12-10 | 2015-01-14 | Achillion Pharmaceuticals Inc | New 4-amino-4-oxobutanoyl peptides as inhibitors of viral replication |
-
2014
- 2014-03-14 EP EP14722457.0A patent/EP2970195B1/en not_active Not-in-force
- 2014-03-14 US US14/211,510 patent/US9115175B2/en not_active Expired - Fee Related
- 2014-03-14 WO PCT/US2014/028278 patent/WO2014152928A2/en active Application Filing
- 2014-03-14 CN CN201480028569.7A patent/CN105408317A/en active Pending
- 2014-03-14 EA EA201591722A patent/EA201591722A1/en unknown
- 2014-03-14 AU AU2014236502A patent/AU2014236502A1/en not_active Abandoned
- 2014-03-14 KR KR1020157028998A patent/KR20160005334A/en not_active Application Discontinuation
- 2014-03-14 SG SG11201507469RA patent/SG11201507469RA/en unknown
- 2014-03-14 JP JP2016502751A patent/JP2016515139A/en active Pending
- 2014-03-14 BR BR112015023343A patent/BR112015023343A2/en not_active IP Right Cessation
- 2014-03-14 CA CA2905433A patent/CA2905433A1/en not_active Abandoned
-
2015
- 2015-07-20 US US14/803,234 patent/US9481708B2/en not_active Expired - Fee Related
- 2015-09-07 IL IL241287A patent/IL241287A0/en unknown
- 2015-09-14 PH PH12015502121A patent/PH12015502121A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2970195B1 (en) | 2017-08-02 |
| CN105408317A (en) | 2016-03-16 |
| WO2014152928A2 (en) | 2014-09-25 |
| US9481708B2 (en) | 2016-11-01 |
| PH12015502121A1 (en) | 2016-01-25 |
| US20140275480A1 (en) | 2014-09-18 |
| JP2016515139A (en) | 2016-05-26 |
| IL241287A0 (en) | 2015-11-30 |
| AU2014236502A1 (en) | 2015-10-01 |
| CA2905433A1 (en) | 2014-09-25 |
| BR112015023343A2 (en) | 2017-07-18 |
| US20150322109A1 (en) | 2015-11-12 |
| WO2014152928A3 (en) | 2015-01-08 |
| EP2970195A2 (en) | 2016-01-20 |
| US9115175B2 (en) | 2015-08-25 |
| EA201591722A1 (en) | 2016-02-29 |
| KR20160005334A (en) | 2016-01-14 |
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