SG11201507462QA - Compositions and methods for live, attenuated alphavirus formulations - Google Patents

Compositions and methods for live, attenuated alphavirus formulations

Info

Publication number
SG11201507462QA
SG11201507462QA SG11201507462QA SG11201507462QA SG11201507462QA SG 11201507462Q A SG11201507462Q A SG 11201507462QA SG 11201507462Q A SG11201507462Q A SG 11201507462QA SG 11201507462Q A SG11201507462Q A SG 11201507462QA SG 11201507462Q A SG11201507462Q A SG 11201507462QA
Authority
SG
Singapore
Prior art keywords
live
compositions
methods
attenuated alphavirus
formulations
Prior art date
Application number
SG11201507462QA
Inventor
Dan T Stinchcomb
Jill A Livengood
Laszlo Varga
Original Assignee
Takeda Vaccines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50489420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201507462Q(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Vaccines Inc filed Critical Takeda Vaccines Inc
Publication of SG11201507462QA publication Critical patent/SG11201507462QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/36011Togaviridae
    • C12N2770/36111Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201507462QA 2013-03-14 2014-03-13 Compositions and methods for live, attenuated alphavirus formulations SG11201507462QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361784122P 2013-03-14 2013-03-14
PCT/US2014/026570 WO2014151855A1 (en) 2013-03-14 2014-03-13 Compositions and methods for live, attenuated alphavirus formulations

Publications (1)

Publication Number Publication Date
SG11201507462QA true SG11201507462QA (en) 2015-10-29

Family

ID=50489420

Family Applications (3)

Application Number Title Priority Date Filing Date
SG10201909051Q SG10201909051QA (en) 2013-03-14 2014-03-13 Compositions and methods for live, attenuated alphavirus formulations
SG10201801459SA SG10201801459SA (en) 2013-03-14 2014-03-13 Compositions and methods for live, attenuated alphavirus formulations
SG11201507462QA SG11201507462QA (en) 2013-03-14 2014-03-13 Compositions and methods for live, attenuated alphavirus formulations

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SG10201909051Q SG10201909051QA (en) 2013-03-14 2014-03-13 Compositions and methods for live, attenuated alphavirus formulations
SG10201801459SA SG10201801459SA (en) 2013-03-14 2014-03-13 Compositions and methods for live, attenuated alphavirus formulations

Country Status (20)

Country Link
US (2) US10137186B2 (en)
EP (2) EP3603667A1 (en)
JP (3) JP6426695B2 (en)
KR (1) KR20160003662A (en)
CN (2) CN105377293B (en)
AP (1) AP2015008733A0 (en)
AU (2) AU2014236804B2 (en)
BR (1) BR112015023205A2 (en)
CA (1) CA2903711A1 (en)
CR (1) CR20150553A (en)
DO (1) DOP2015000226A (en)
EC (1) ECSP20007842A (en)
HK (1) HK1220358A1 (en)
MX (2) MX361342B (en)
MY (1) MY178476A (en)
NZ (1) NZ631012A (en)
PH (1) PH12015502115B1 (en)
SG (3) SG10201909051QA (en)
TW (2) TWI649087B (en)
WO (1) WO2014151855A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201909051QA (en) * 2013-03-14 2019-11-28 Takeda Vaccines Inc Compositions and methods for live, attenuated alphavirus formulations
EP3087188A1 (en) 2013-12-23 2016-11-02 Theravectys Lyophilized lentiviral vector particles, compositions and methods
WO2017172643A1 (en) * 2016-03-31 2017-10-05 Takeda Vaccines, Inc. Compositions and methods for stabilizing alphaviruses with improved formulations
NL2022538B1 (en) * 2019-02-08 2020-08-19 Academisch Ziekenhuis Groningen Methods for providing purified viral particles of Semliki Forest Virus (SFV), preparations obtainable thereby, and uses thereof.
CA3174826A1 (en) * 2021-01-19 2022-07-28 Katsuro HAGIWARA Virus stabilizer, gelatin hydrolysate for virus stabilizer, and virus-containing composition

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338335A (en) * 1980-02-05 1982-07-06 Merck & Co., Inc. Vaccine stabilizer containing L-glutamic acid and L-arginine
RU2035508C1 (en) * 1991-08-16 1995-05-20 Институт органической химии СО РАН Nutrient medium for stabilization of equine venezuelan encephalitis virus
US5545555A (en) * 1994-07-25 1996-08-13 Microtest, Inc. Microbial transport media
WO1996017072A2 (en) * 1994-11-30 1996-06-06 Chiron Viagene, Inc. Recombinant alphavirus vectors
US6458560B1 (en) * 1996-04-05 2002-10-01 Chiron Corporation Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
US6290967B1 (en) * 1996-12-20 2001-09-18 Merck & Co., Inc. Stabilizers for lyophilized vaccines
US6210683B1 (en) 1997-09-05 2001-04-03 Merck & Co., Inc. Stabilizers containing recombinant human serum albumin for live virus vaccines
DE19803453A1 (en) * 1998-01-30 1999-08-12 Boehringer Ingelheim Int vaccine
EP1100944A1 (en) * 1998-07-30 2001-05-23 The Johns Hopkins University School Of Medicine Targeted alphavirus and alphaviral vectors
US6869907B2 (en) * 2000-05-02 2005-03-22 Pentax Corporation Color-image-forming medium
FR2814957B1 (en) 2000-10-06 2002-12-20 Aventis Pasteur VACCINE COMPOSITION AND STABILIZATION METHOD
EP1453537A1 (en) * 2001-12-12 2004-09-08 FH Faulding & Co. Limited Composition for viral preservation
WO2003087327A2 (en) * 2002-04-11 2003-10-23 Medimmune Vaccines, Inc. Preservation of bioactive materials by freeze dried foam
US8603796B2 (en) 2003-12-17 2013-12-10 Wyeth Llc Method for producing storage stable viruses and immunogenic compositions thereof
CN101516395B (en) * 2006-09-01 2014-03-26 伯哈拉特生物技术国际有限公司 A vaccine for chikungunya virus infection
DK2099485T3 (en) * 2006-11-03 2018-05-22 Alphavax Inc Alphavirus and alphavirus replica particle formulations and associated methods
TWI417113B (en) 2006-11-07 2013-12-01 Acambis Inc Stabilization of vaccines by lyophilization
AU2008279576C1 (en) 2007-04-06 2014-01-23 Takeda Vaccines, Inc. Methods and compositions for live attenuated viruses
CA2698392C (en) 2007-09-04 2019-12-03 Baoming Jiang Thermal inactivation of rotavirus
KR101679812B1 (en) 2007-09-14 2016-11-28 사노피 파스테르 바이오로직스, 엘엘씨 Pharmaceutical compositions containing clostridium difficile toxoids a and b
EP3085787B1 (en) 2008-01-24 2020-10-28 The Board of Regents of the University of Texas System Attenuated recombinant alphaviruses incapable of replicating in mosquitoes and uses thereof
EP2376107B1 (en) 2008-12-09 2014-05-21 Coley Pharmaceutical Group, Inc. Immunostimulatory oligonucleotides
EP2519539A4 (en) 2009-12-28 2013-11-13 Ligocyte Pharmaceuticals Inc Methods for stabilizing influenza antigen enveloped virus-based virus-like particle solutions
CN102939104A (en) 2010-06-01 2013-02-20 诺华有限公司 Concentration of vaccine antigens with lyophilization
SG10201909051QA (en) 2013-03-14 2019-11-28 Takeda Vaccines Inc Compositions and methods for live, attenuated alphavirus formulations

Also Published As

Publication number Publication date
KR20160003662A (en) 2016-01-11
US10806781B2 (en) 2020-10-20
JP2016513658A (en) 2016-05-16
JP6761015B2 (en) 2020-09-23
US10137186B2 (en) 2018-11-27
SG10201801459SA (en) 2018-03-28
CN105377293B (en) 2020-07-17
JP2019031543A (en) 2019-02-28
DOP2015000226A (en) 2016-02-29
AP2015008733A0 (en) 2015-09-30
ECSP20007842A (en) 2020-09-30
HK1220358A1 (en) 2017-05-05
SG10201909051QA (en) 2019-11-28
NZ631012A (en) 2017-08-25
CA2903711A1 (en) 2014-09-25
PH12015502115A1 (en) 2016-01-25
AU2018236897B2 (en) 2020-09-10
TW201900192A (en) 2019-01-01
AU2018236897A1 (en) 2018-10-18
CR20150553A (en) 2015-12-01
MX2015012894A (en) 2016-04-04
AU2014236804A1 (en) 2015-10-01
BR112015023205A2 (en) 2017-07-18
PH12015502115B1 (en) 2016-01-25
TW201513875A (en) 2015-04-16
TWI649087B (en) 2019-02-01
MX361342B (en) 2018-12-04
EP2968515A1 (en) 2016-01-20
MX2018014977A (en) 2022-06-27
EP2968515B1 (en) 2019-05-08
AU2014236804B2 (en) 2018-12-13
JP2020193231A (en) 2020-12-03
US20140271715A1 (en) 2014-09-18
WO2014151855A1 (en) 2014-09-25
JP6426695B2 (en) 2018-11-21
US20190134182A1 (en) 2019-05-09
CN105377293A (en) 2016-03-02
MY178476A (en) 2020-10-14
CN111729077A (en) 2020-10-02
EP3603667A1 (en) 2020-02-05

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