SG11201506146TA - Highly selective nucleic acid amplification primers - Google Patents
Highly selective nucleic acid amplification primersInfo
- Publication number
- SG11201506146TA SG11201506146TA SG11201506146TA SG11201506146TA SG11201506146TA SG 11201506146T A SG11201506146T A SG 11201506146TA SG 11201506146T A SG11201506146T A SG 11201506146TA SG 11201506146T A SG11201506146T A SG 11201506146TA SG 11201506146T A SG11201506146T A SG 11201506146TA
- Authority
- SG
- Singapore
- Prior art keywords
- nucleic acid
- acid amplification
- highly selective
- amplification primers
- selective nucleic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/161—Modifications characterised by incorporating target specific and non-target specific sites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/191—Modifications characterised by incorporating an adaptor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/125—Allele specific primer extension
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/131—Allele specific probes
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361762117P | 2013-02-07 | 2013-02-07 | |
| PCT/US2014/015351 WO2014124290A1 (en) | 2013-02-07 | 2014-02-07 | Highly selective nucleic acid amplification primers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201506146TA true SG11201506146TA (en) | 2015-09-29 |
Family
ID=51300164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201506146TA SG11201506146TA (en) | 2013-02-07 | 2014-02-07 | Highly selective nucleic acid amplification primers |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US9909159B2 (en) |
| EP (2) | EP2953958B1 (en) |
| JP (1) | JP6544861B2 (en) |
| KR (2) | KR102222546B1 (en) |
| CN (2) | CN110195097A (en) |
| AU (1) | AU2014214725B2 (en) |
| CA (2) | CA2900259C (en) |
| IL (2) | IL240347B (en) |
| SG (1) | SG11201506146TA (en) |
| WO (1) | WO2014124290A1 (en) |
| ZA (1) | ZA201505637B (en) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015077717A1 (en) | 2013-11-25 | 2015-05-28 | The Broad Institute Inc. | Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status |
| US11725237B2 (en) | 2013-12-05 | 2023-08-15 | The Broad Institute Inc. | Polymorphic gene typing and somatic change detection using sequencing data |
| NZ721908A (en) | 2013-12-20 | 2022-12-23 | Massachusetts Gen Hospital | Combination therapy with neoantigen vaccine |
| US10975442B2 (en) | 2014-12-19 | 2021-04-13 | Massachusetts Institute Of Technology | Molecular biomarkers for cancer immunotherapy |
| EP3234130B1 (en) | 2014-12-19 | 2020-11-25 | The Broad Institute, Inc. | Methods for profiling the t-cell- receptor repertoire |
| CN108025048B (en) | 2015-05-20 | 2022-10-25 | 博德研究所 | Shared novel antigens |
| CN105274096A (en) * | 2015-09-07 | 2016-01-27 | 中国人民解放军第三军医大学第一附属医院 | Bridge type fluorescent probe with bridge type sequence zone doping into mismatched bases and application and method |
| AU2017246663B2 (en) * | 2016-04-07 | 2022-09-01 | Rutgers, The State University Of New Jersey | Multiplex nucleic acid assay methods capable of detecting closely related alleles, and reagents therefor |
| WO2017201239A1 (en) * | 2016-05-18 | 2017-11-23 | Integrated Nano-Technologies, Inc. | Method for detection of a pcr product |
| CN106399484B (en) * | 2016-08-31 | 2020-03-24 | 中国人民解放军第三军医大学第一附属医院 | Double-bubble fluorescent probe and application and kit thereof |
| US11434540B2 (en) * | 2016-11-15 | 2022-09-06 | Arizona Board Of Regents On Behalf Of Arizona State University | Ultraspecific nucleic acid sensors for low-cost liquid biopsies |
| EP3574116A1 (en) | 2017-01-24 | 2019-12-04 | The Broad Institute, Inc. | Compositions and methods for detecting a mutant variant of a polynucleotide |
| EP3601560A1 (en) * | 2017-03-20 | 2020-02-05 | Illumina, Inc. | Methods and compositions for preparing nucleic acid libraries |
| CA3062708A1 (en) * | 2017-05-23 | 2018-11-29 | Rutgers, The State University Of New Jersey | Target mediated in situ signal amplification with dual interacting hairpin probes |
| EP3737773B1 (en) * | 2018-01-12 | 2023-04-12 | Natera, Inc. | Novel primers and uses thereof |
| WO2019150414A1 (en) * | 2018-01-30 | 2019-08-08 | 学校法人 慶應義塾 | Method for detecting nucleic acid |
| US11306350B2 (en) * | 2018-09-30 | 2022-04-19 | Maccura Biotechnology Co., Ltd. | Primers, compositions, and methods for nucleic acid sequence variation detection |
| CN111647650B (en) * | 2020-07-06 | 2023-06-27 | 河南赛诺特生物技术有限公司 | Primer, primer probe composition and kit for detecting V600E mutation of human B-raf gene |
| CN112575072B (en) * | 2020-12-29 | 2021-12-31 | 苏州科贝生物技术有限公司 | Primer pair and kit for detecting BRAF gene V600E mutation in plasma free DNA |
| US20230112648A1 (en) * | 2021-09-17 | 2023-04-13 | Homology Medicines, Inc. | Non-naturally occurring polyadenylation elements and methods of use thereof |
| CN116121453A (en) * | 2022-11-11 | 2023-05-16 | 重庆浦济生命科技有限公司 | Improved structure of high-sensitivity fluorescent PCR detection primer and probe and application thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5866336A (en) * | 1996-07-16 | 1999-02-02 | Oncor, Inc. | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
| US6207379B1 (en) | 1998-09-11 | 2001-03-27 | One Lambda | Method for amplification of DNA |
| US6277607B1 (en) | 1999-05-24 | 2001-08-21 | Sanjay Tyagi | High specificity primers, amplification methods and kits |
| US7198897B2 (en) | 2001-12-19 | 2007-04-03 | Brandeis University | Late-PCR |
| WO2006095981A1 (en) * | 2005-03-05 | 2006-09-14 | Seegene, Inc. | Processes using dual specificity oligonucleotide and dual specificity oligonucleotide |
| WO2006095941A1 (en) | 2005-03-05 | 2006-09-14 | Seegene, Inc. | Processes using dual specificity oligonucleotide and dual specificity oligonucleotide |
| WO2006133184A2 (en) * | 2005-06-07 | 2006-12-14 | Eragen Biosciences, Inc. | Methods for detection and typing of nucleic acids |
| KR100860619B1 (en) | 2006-02-23 | 2008-09-29 | 주식회사 씨젠 | Oligonucleotides for Detecting Nucleic Acids of Pathogen Causing Sexually Transmitted Diseases |
| KR100881924B1 (en) * | 2007-03-14 | 2009-02-04 | 주식회사 씨젠 | Method for Detecting Nucleotide Variations Using Labelled Primers |
| ES2610616T3 (en) | 2009-03-26 | 2017-04-28 | Xiamen Amoy Diagnostics Co., Ltd | Primer with loop conformation used in the amplification of nucleic acids and the use thereof |
| JP4528885B1 (en) * | 2009-06-29 | 2010-08-25 | 株式会社東芝 | Sample analysis method and assay kit used therefor |
| WO2011027966A2 (en) * | 2009-09-03 | 2011-03-10 | Seegene, Inc. | Td probe and its uses |
| JP5938348B2 (en) | 2009-10-23 | 2016-06-22 | ルミネックス コーポレーション | Amplification primers containing non-standard bases for increased reaction specificity |
| KR20110050327A (en) * | 2009-11-07 | 2011-05-13 | 주식회사 씨젠 | T h d primer target detection |
| WO2011078441A1 (en) * | 2009-12-21 | 2011-06-30 | Seegene, Inc. | Tsg primer target detection |
| SG192736A1 (en) | 2011-02-14 | 2013-09-30 | Swift Biosciences Inc | Polynucleotide primers and probes |
| KR102085119B1 (en) | 2012-02-20 | 2020-03-05 | 스피디엑스 피티와이 리미티드 | Detection of nucleic acids |
-
2014
- 2014-02-07 AU AU2014214725A patent/AU2014214725B2/en active Active
- 2014-02-07 CN CN201910003110.6A patent/CN110195097A/en active Pending
- 2014-02-07 CA CA2900259A patent/CA2900259C/en active Active
- 2014-02-07 CN CN201480019974.2A patent/CN105102467B/en active Active
- 2014-02-07 KR KR1020157024265A patent/KR102222546B1/en active Application Filing
- 2014-02-07 WO PCT/US2014/015351 patent/WO2014124290A1/en active Application Filing
- 2014-02-07 SG SG11201506146TA patent/SG11201506146TA/en unknown
- 2014-02-07 JP JP2015557131A patent/JP6544861B2/en active Active
- 2014-02-07 EP EP14748774.8A patent/EP2953958B1/en active Active
- 2014-02-07 EP EP18156307.3A patent/EP3346016B1/en active Active
- 2014-02-07 KR KR1020217005395A patent/KR102351434B1/en active IP Right Grant
- 2014-02-07 CA CA3096478A patent/CA3096478C/en active Active
- 2014-02-07 US US14/766,139 patent/US9909159B2/en active Active
-
2015
- 2015-08-04 IL IL240347A patent/IL240347B/en active IP Right Grant
- 2015-08-05 ZA ZA2015/05637A patent/ZA201505637B/en unknown
-
2018
- 2018-01-22 US US15/877,007 patent/US10815512B2/en active Active
-
2019
- 2019-01-30 IL IL264555A patent/IL264555B/en unknown
-
2020
- 2020-10-23 US US17/078,463 patent/US11111515B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20150361475A1 (en) | 2015-12-17 |
| ZA201505637B (en) | 2016-07-27 |
| IL240347B (en) | 2019-02-28 |
| IL264555A (en) | 2019-02-28 |
| CA3096478C (en) | 2021-06-22 |
| US20180216151A1 (en) | 2018-08-02 |
| US9909159B2 (en) | 2018-03-06 |
| EP3346016B1 (en) | 2019-10-02 |
| KR20210024220A (en) | 2021-03-04 |
| CN105102467A (en) | 2015-11-25 |
| JP2016506748A (en) | 2016-03-07 |
| KR20150115932A (en) | 2015-10-14 |
| EP2953958A4 (en) | 2016-08-17 |
| CN110195097A (en) | 2019-09-03 |
| IL264555B (en) | 2021-10-31 |
| AU2014214725A1 (en) | 2015-08-20 |
| KR102351434B1 (en) | 2022-01-17 |
| US20210164009A1 (en) | 2021-06-03 |
| EP2953958B1 (en) | 2018-04-11 |
| JP6544861B2 (en) | 2019-07-17 |
| AU2014214725B2 (en) | 2018-04-05 |
| EP3346016A1 (en) | 2018-07-11 |
| US10815512B2 (en) | 2020-10-27 |
| CA2900259A1 (en) | 2014-08-14 |
| US11111515B2 (en) | 2021-09-07 |
| CN105102467B (en) | 2019-01-22 |
| IL240347A0 (en) | 2015-09-24 |
| NZ710851A (en) | 2020-11-27 |
| CA2900259C (en) | 2020-12-29 |
| EP2953958A1 (en) | 2015-12-16 |
| WO2014124290A1 (en) | 2014-08-14 |
| KR102222546B1 (en) | 2021-03-08 |
| CA3096478A1 (en) | 2014-08-14 |
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