SG11201505627RA - INHIBITION OF TISSUE FACTOR PATHWAY INHIBITOR WITH FACTOR Xa DERIVATIVES - Google Patents
INHIBITION OF TISSUE FACTOR PATHWAY INHIBITOR WITH FACTOR Xa DERIVATIVESInfo
- Publication number
- SG11201505627RA SG11201505627RA SG11201505627RA SG11201505627RA SG11201505627RA SG 11201505627R A SG11201505627R A SG 11201505627RA SG 11201505627R A SG11201505627R A SG 11201505627RA SG 11201505627R A SG11201505627R A SG 11201505627RA SG 11201505627R A SG11201505627R A SG 11201505627RA
- Authority
- SG
- Singapore
- Prior art keywords
- factor
- inhibition
- derivatives
- pathway inhibitor
- tissue
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6432—Coagulation factor Xa (3.4.21.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21006—Coagulation factor Xa (3.4.21.6)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361756359P | 2013-01-24 | 2013-01-24 | |
PCT/US2013/030927 WO2014116275A1 (en) | 2013-01-24 | 2013-03-13 | INHIBITION OF TISSUE FACTOR PATHWAY INHIBITOR WITH FACTOR Xa DERIVATIVES |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201505627RA true SG11201505627RA (en) | 2015-08-28 |
Family
ID=47997935
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201705189XA SG10201705189XA (en) | 2013-01-24 | 2013-03-13 | INHIBITION OF TISSUE FACTOR PATHWAY INHIBITOR WITH FACTOR Xa DERIVATIVES |
SG11201505627RA SG11201505627RA (en) | 2013-01-24 | 2013-03-13 | INHIBITION OF TISSUE FACTOR PATHWAY INHIBITOR WITH FACTOR Xa DERIVATIVES |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201705189XA SG10201705189XA (en) | 2013-01-24 | 2013-03-13 | INHIBITION OF TISSUE FACTOR PATHWAY INHIBITOR WITH FACTOR Xa DERIVATIVES |
Country Status (9)
Country | Link |
---|---|
US (3) | US20150352194A1 (en) |
EP (1) | EP2948168B1 (en) |
CN (1) | CN105025920A (en) |
AU (1) | AU2013375294B2 (en) |
CA (1) | CA2898975C (en) |
HK (1) | HK1217657A1 (en) |
IL (1) | IL240063B (en) |
SG (2) | SG10201705189XA (en) |
WO (1) | WO2014116275A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA037815B1 (en) | 2016-06-17 | 2021-05-25 | Портола Фармасьютикалз, Инк. | PREPARATION OF FACTOR Xa DERIVATIVES |
FR3064917A1 (en) * | 2017-04-07 | 2018-10-12 | Universite Grenoble Alpes | X MUTE FACTOR |
EP4270010A1 (en) * | 2020-12-28 | 2023-11-01 | Fujimori Kogyo Co., Ltd. | Method for evaluating blood coagulation performance, and method for inspecting risk of thrombosis |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EE200200538A (en) * | 2000-03-22 | 2004-04-15 | Octagene Gmbh | Production of recombinant blood coagulation factors in human cell lines |
KR20170100071A (en) * | 2007-09-28 | 2017-09-01 | 포톨라 파마슈티컬스, 인코포레이티드 | ANTIDOTES FOR FACTOR Xa INHIBITORS AND METHODS OF USING THE SAME |
US8268783B2 (en) * | 2007-09-28 | 2012-09-18 | Portola Pharmaceuticals, Inc. | Antidotes for factor Xa inhibitors and methods of using the same |
MX2011004907A (en) * | 2008-11-14 | 2011-07-29 | Portola Pharm Inc | Antidotes for factor xa inhibitors and methods of using the same in combination with blood coagulating agents. |
ES2605801T3 (en) * | 2009-07-15 | 2017-03-16 | Portola Pharmaceuticals, Inc. | Unit dose formulation of antidote for factor Xa inhibitors for use in the prevention of bleeding |
FR2972114B1 (en) * | 2011-03-01 | 2013-03-15 | Univ Grenoble 1 | A NEW MOLECULAR LURE PROCOAGULANT FOR THE TREATMENT OF HEMOPHILS A OR B WITH OR WITHOUT INHIBITOR |
EA037815B1 (en) * | 2016-06-17 | 2021-05-25 | Портола Фармасьютикалз, Инк. | PREPARATION OF FACTOR Xa DERIVATIVES |
-
2013
- 2013-03-13 US US14/762,098 patent/US20150352194A1/en not_active Abandoned
- 2013-03-13 SG SG10201705189XA patent/SG10201705189XA/en unknown
- 2013-03-13 CA CA2898975A patent/CA2898975C/en active Active
- 2013-03-13 SG SG11201505627RA patent/SG11201505627RA/en unknown
- 2013-03-13 WO PCT/US2013/030927 patent/WO2014116275A1/en active Application Filing
- 2013-03-13 AU AU2013375294A patent/AU2013375294B2/en not_active Ceased
- 2013-03-13 EP EP13712086.1A patent/EP2948168B1/en active Active
- 2013-03-13 CN CN201380073398.5A patent/CN105025920A/en active Pending
-
2015
- 2015-07-21 IL IL240063A patent/IL240063B/en active IP Right Grant
-
2016
- 2016-05-20 HK HK16105784.1A patent/HK1217657A1/en not_active IP Right Cessation
-
2018
- 2018-03-12 US US15/919,014 patent/US20180333469A1/en not_active Abandoned
-
2021
- 2021-02-16 US US17/176,939 patent/US20210379163A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2014116275A1 (en) | 2014-07-31 |
HK1217657A1 (en) | 2017-01-20 |
EP2948168B1 (en) | 2018-07-18 |
CA2898975A1 (en) | 2014-07-31 |
IL240063A0 (en) | 2015-09-24 |
IL240063B (en) | 2020-03-31 |
EP2948168A1 (en) | 2015-12-02 |
CA2898975C (en) | 2021-06-15 |
CN105025920A (en) | 2015-11-04 |
US20150352194A1 (en) | 2015-12-10 |
AU2013375294B2 (en) | 2018-08-09 |
US20210379163A1 (en) | 2021-12-09 |
AU2013375294A1 (en) | 2015-08-27 |
SG10201705189XA (en) | 2017-07-28 |
US20180333469A1 (en) | 2018-11-22 |
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