SG11201504300VA - Accelerated prediction of cancer progression and response to treatment - Google Patents

Accelerated prediction of cancer progression and response to treatment

Info

Publication number
SG11201504300VA
SG11201504300VA SG11201504300VA SG11201504300VA SG11201504300VA SG 11201504300V A SG11201504300V A SG 11201504300VA SG 11201504300V A SG11201504300V A SG 11201504300VA SG 11201504300V A SG11201504300V A SG 11201504300VA SG 11201504300V A SG11201504300V A SG 11201504300VA
Authority
SG
Singapore
Prior art keywords
response
treatment
cancer progression
prediction
accelerated
Prior art date
Application number
SG11201504300VA
Inventor
Indrajit Sinha
Original Assignee
Biomedcore Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomedcore Inc filed Critical Biomedcore Inc
Publication of SG11201504300VA publication Critical patent/SG11201504300VA/en

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • G01N33/5088Supracellular entities, e.g. tissue, organisms of vertebrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43526Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/70Mechanisms involved in disease identification
    • G01N2800/7023(Hyper)proliferation
    • G01N2800/7028Cancer
SG11201504300VA 2012-12-02 2013-12-02 Accelerated prediction of cancer progression and response to treatment SG11201504300VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261732375P 2012-12-02 2012-12-02
PCT/IB2013/060580 WO2014083555A1 (en) 2012-12-02 2013-12-02 Accelerated prediction of cancer progression and response to treatment

Publications (1)

Publication Number Publication Date
SG11201504300VA true SG11201504300VA (en) 2015-07-30

Family

ID=50827252

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201504300VA SG11201504300VA (en) 2012-12-02 2013-12-02 Accelerated prediction of cancer progression and response to treatment

Country Status (7)

Country Link
US (1) US10760060B2 (en)
EP (1) EP2925890A4 (en)
JP (1) JP6430392B2 (en)
CN (1) CN105121657A (en)
CA (1) CA2893549C (en)
SG (1) SG11201504300VA (en)
WO (1) WO2014083555A1 (en)

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WO2016077692A1 (en) * 2014-11-14 2016-05-19 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Apparatus, kit and method for manipulating small model organisms
US20170370709A1 (en) * 2015-06-08 2017-12-28 Trustees Of Tufts College Imaging System To Characterize Dynamic Changes In Cell And Particle Characteristics
US10453551B2 (en) 2016-06-08 2019-10-22 X Development Llc Simulating living cell in silico
WO2018063098A1 (en) * 2016-09-30 2018-04-05 Nanyang Technological University Apparatus for embryo biopsy
EP3542290B1 (en) * 2016-11-17 2024-01-03 NantBio, Inc. Validation of inferred anticancer pathways
GB201710955D0 (en) 2017-07-07 2017-08-23 Insphero Ag Microtissue compartment device
KR101965299B1 (en) * 2017-11-14 2019-04-03 주식회사 수젠텍 Assembly type blot strip device
CN110402853B (en) * 2018-04-28 2022-01-07 义慧科技(深圳)有限公司 Detection model for tumor killing ability of immune cells and construction method and application thereof
CN108841869B (en) * 2018-05-31 2022-05-06 上海交通大学医学院附属瑞金医院 Construction method and application of zebra fish NK/TCL tumor model
CN112094890A (en) * 2019-06-17 2020-12-18 南京尧顺禹生物科技有限公司 Method for quantitatively evaluating proliferation of tumor cells transplanted into zebra fish embryo
US20210251183A1 (en) * 2020-02-03 2021-08-19 Korea Research Institute Of Standards And Science Monitoring method of heart rate for toxicity test using high-speed digital holography

Family Cites Families (11)

* Cited by examiner, † Cited by third party
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ES2286908T3 (en) * 1998-12-01 2007-12-01 Phylonix Pharmaceuticals Inc. METHODS TO ENTER HETEROLOGICAL CELLS IN FISH.
AU4487900A (en) 1999-04-23 2000-11-10 Monica Palacios-Boyce Microelectromechanical devices useful for manipulating cells or embryos, kits thereof, methods of making same, and methods of use thereof
AU2002246527A1 (en) 2000-11-28 2002-08-06 Georgetown University Cell transformation using a single chip silicon microfabricated array incorporating integrated micro-piercing injectors
US20020116732A1 (en) 2001-02-13 2002-08-22 Leandro Christmann Microinjection assembly and methods for microinjecting and reimplanting avian eggs
US7339090B2 (en) 2001-02-13 2008-03-04 Avigenics, Inc. Microinjection devices and methods of use
US7190449B2 (en) 2002-10-28 2007-03-13 Nanopoint, Inc. Cell tray
US20050112030A1 (en) 2003-08-21 2005-05-26 Gaus Stephanie E. Meshwell plates
US20080077999A1 (en) * 2004-03-23 2008-03-27 Eisai R&D Management Co., Ltd. Using Nonhuman Animal Model, Method of Measuring Transcription Activity Method of Measuring Cell Quantity and Method of Measuring Tumor Volume
ES2259566B1 (en) 2005-03-29 2007-08-01 Instituto Nacional De Investigacion Y Tecnologia Agraria Y Alimentaria-Inia SUPPLEMENTATION FOR EMBRYO HANDLING AND / OR CELLULAR MEDIA.
EP2329817A1 (en) * 2009-09-04 2011-06-08 Ernst-Moritz-Arndt-Universität Greifswald Retinoic acid receptor antagonists, miR-10a inhibitors and inhibitors of HOXB1 or HOXB3 repressors for treating pancreatic cancer
GB2479521A (en) 2010-03-19 2011-10-19 Univ Leiden Array microinjection apparatus and methods for single cells or embryos

Also Published As

Publication number Publication date
JP2016501021A (en) 2016-01-18
WO2014083555A1 (en) 2014-06-05
EP2925890A1 (en) 2015-10-07
CA2893549A1 (en) 2014-06-05
EP2925890A4 (en) 2016-06-01
CN105121657A (en) 2015-12-02
JP6430392B2 (en) 2018-11-28
CA2893549C (en) 2023-05-09
US20150315546A1 (en) 2015-11-05
US10760060B2 (en) 2020-09-01

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