SG11201503876YA - Method for eliciting an immune response to an immunogen - Google Patents

Method for eliciting an immune response to an immunogen

Info

Publication number
SG11201503876YA
SG11201503876YA SG11201503876YA SG11201503876YA SG11201503876YA SG 11201503876Y A SG11201503876Y A SG 11201503876YA SG 11201503876Y A SG11201503876Y A SG 11201503876YA SG 11201503876Y A SG11201503876Y A SG 11201503876YA SG 11201503876Y A SG11201503876Y A SG 11201503876YA
Authority
SG
Singapore
Prior art keywords
eliciting
immunogen
immune response
immune
response
Prior art date
Application number
SG11201503876YA
Other languages
English (en)
Inventor
Madhavan Nallani
Fabien Decaillot
Zhikang Fu
Xingfang Su
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Priority to SG11201503876YA priority Critical patent/SG11201503876YA/en
Publication of SG11201503876YA publication Critical patent/SG11201503876YA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
SG11201503876YA 2012-11-19 2013-11-11 Method for eliciting an immune response to an immunogen SG11201503876YA (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SG11201503876YA SG11201503876YA (en) 2012-11-19 2013-11-11 Method for eliciting an immune response to an immunogen

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SG2012084836 2012-11-19
SG11201503876YA SG11201503876YA (en) 2012-11-19 2013-11-11 Method for eliciting an immune response to an immunogen
PCT/SG2013/000478 WO2014077781A1 (en) 2012-11-19 2013-11-11 Method for eliciting an immune response to an immunogen

Publications (1)

Publication Number Publication Date
SG11201503876YA true SG11201503876YA (en) 2015-06-29

Family

ID=54321064

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201503876YA SG11201503876YA (en) 2012-11-19 2013-11-11 Method for eliciting an immune response to an immunogen
SG10201704135QA SG10201704135QA (en) 2012-11-19 2013-11-11 Method For Eliciting An Immune Response To An Immunogen

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201704135QA SG10201704135QA (en) 2012-11-19 2013-11-11 Method For Eliciting An Immune Response To An Immunogen

Country Status (8)

Country Link
US (3) US9962438B2 (ja)
EP (1) EP2919758B1 (ja)
JP (3) JP6453757B2 (ja)
CN (2) CN111450060A (ja)
MY (1) MY175416A (ja)
PH (1) PH12015501101B1 (ja)
SG (2) SG11201503876YA (ja)
WO (1) WO2014077781A1 (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201503876YA (en) * 2012-11-19 2015-06-29 Agency Science Tech & Res Method for eliciting an immune response to an immunogen
US10821078B2 (en) * 2016-06-30 2020-11-03 Northwestern University Nanostructure enhanced targeting (NSET) of inflammatory cells
EP3668927B1 (en) * 2017-09-12 2024-03-20 ETH Zurich Transmembrane ph-gradient polymersomes for the quantification of ammonia in body fluids
JP7542257B2 (ja) * 2018-01-25 2024-08-30 エイシーエム バイオラブズ プライベート リミテッド 可溶化された封入抗原を含むポリマーソーム、ならびにその作製および使用方法
EP3849600A1 (en) * 2018-09-12 2021-07-21 ACM Biolabs Pte Ltd Polymersomes comprising a covalently bound antigen as well as methods of making and uses thereof
CN110327298A (zh) * 2019-07-30 2019-10-15 天津大学 基于pcl-peg聚合物囊泡的长循环靶向基因载体的制备方法
WO2021019102A2 (en) * 2019-08-01 2021-02-04 Acm Biolabs Pte Ltd A method of eliciting an immune response by administering a population of polymersomes having an associated antigen together with a population of polymersomes having an associated adjuvant as well as compositions comprising the two populations of polymersomes
WO2021214339A2 (en) 2020-04-24 2021-10-28 Acm Biolabs Pte Ltd Vaccine against human-pathogenic coronaviruses
WO2022123070A1 (en) 2020-12-11 2022-06-16 Acm Biolabs Pte Ltd Modulating th1/th2 immune response by administering two populations of polymersomes having an associated antigen and an associated adjuvant
EP4288033A1 (en) * 2021-02-02 2023-12-13 ACM Biolabs Pte Ltd Sole use of polymersome associated adjuvant for stimulating an immune response
EP4322922A1 (en) 2021-04-12 2024-02-21 ACM Biolabs Pte Ltd Polymersomes comprising a soluble encapsulated polynucleotide and an ionizable lipid as well as methods of making and uses thereof
WO2023161378A1 (en) 2022-02-23 2023-08-31 Acm Biolabs Pte Ltd Polymer-lipid hybrid nanoparticles comprising a lipid and a block copolymer as well as methods of making and uses thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6835394B1 (en) * 1999-12-14 2004-12-28 The Trustees Of The University Of Pennsylvania Polymersomes and related encapsulating membranes
US7682603B2 (en) * 2003-07-25 2010-03-23 The Trustees Of The University Of Pennsylvania Polymersomes incorporating highly emissive probes
US8821859B2 (en) * 2004-05-19 2014-09-02 Agency For Science, Technology And Research Methods and articles for the delivery of therapeutic agents
US20080312581A1 (en) * 2007-06-06 2008-12-18 Biovaluation & Analysis, Inc. Peptosomes for Use in Acoustically Mediated Intracellular Drug Delivery in vivo
CN101854917A (zh) * 2007-07-20 2010-10-06 巴斯夫欧洲公司 包含跨膜转运触发体系的小泡
US8378003B2 (en) * 2007-12-05 2013-02-19 The Board Of Trustees Of The University Of Illinois Highly permeable polymeric membranes
US10364350B2 (en) * 2009-04-20 2019-07-30 Agency For Science, Technology And Research Vesicular system and uses thereof
US8470891B2 (en) * 2009-12-23 2013-06-25 International Business Machines Corporation Biodegradable block polymers for drug delivery, and methods related thereto
EP2542057A4 (en) * 2010-03-02 2014-10-15 Vindico Nanobio Technology Inc COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING INFAMOUS DISEASES
GB201008364D0 (en) * 2010-05-20 2010-07-07 Geneve De Composition and method
SG187669A1 (en) * 2010-08-05 2013-03-28 Agency Science Tech & Res A multicompartmentalized vesicular structure and a method for forming the same
GB201111216D0 (en) * 2011-07-01 2011-08-17 Reckitt & Colman Overseas Composition and method
SG11201503876YA (en) * 2012-11-19 2015-06-29 Agency Science Tech & Res Method for eliciting an immune response to an immunogen
WO2016055611A1 (en) * 2014-10-09 2016-04-14 Universität Basel Self-assembled nanostructures and methods of use thereof
JP7542257B2 (ja) * 2018-01-25 2024-08-30 エイシーエム バイオラブズ プライベート リミテッド 可溶化された封入抗原を含むポリマーソーム、ならびにその作製および使用方法
WO2021019102A2 (en) * 2019-08-01 2021-02-04 Acm Biolabs Pte Ltd A method of eliciting an immune response by administering a population of polymersomes having an associated antigen together with a population of polymersomes having an associated adjuvant as well as compositions comprising the two populations of polymersomes
WO2022123070A1 (en) * 2020-12-11 2022-06-16 Acm Biolabs Pte Ltd Modulating th1/th2 immune response by administering two populations of polymersomes having an associated antigen and an associated adjuvant
EP4288033A1 (en) * 2021-02-02 2023-12-13 ACM Biolabs Pte Ltd Sole use of polymersome associated adjuvant for stimulating an immune response

Also Published As

Publication number Publication date
EP2919758B1 (en) 2020-09-30
EP2919758A1 (en) 2015-09-23
US20180214540A1 (en) 2018-08-02
US20150297711A1 (en) 2015-10-22
JP6777705B2 (ja) 2020-10-28
PH12015501101B1 (en) 2021-08-04
JP2016500071A (ja) 2016-01-07
JP2019011358A (ja) 2019-01-24
US20220133883A1 (en) 2022-05-05
SG10201704135QA (en) 2017-06-29
EP2919758A4 (en) 2016-08-17
CN104936579B (zh) 2020-02-07
CN104936579A (zh) 2015-09-23
JP2020183438A (ja) 2020-11-12
US9962438B2 (en) 2018-05-08
US11241494B2 (en) 2022-02-08
MY175416A (en) 2020-06-24
CN111450060A (zh) 2020-07-28
JP6453757B2 (ja) 2019-01-16
PH12015501101A1 (en) 2015-07-27
WO2014077781A1 (en) 2014-05-22

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