SG11201503448SA - Method for prediction of an immune response against mismatched human leukocyte antigens - Google Patents

Method for prediction of an immune response against mismatched human leukocyte antigens

Info

Publication number
SG11201503448SA
SG11201503448SA SG11201503448SA SG11201503448SA SG11201503448SA SG 11201503448S A SG11201503448S A SG 11201503448SA SG 11201503448S A SG11201503448S A SG 11201503448SA SG 11201503448S A SG11201503448S A SG 11201503448SA SG 11201503448S A SG11201503448S A SG 11201503448SA
Authority
SG
Singapore
Prior art keywords
prediction
immune response
response against
human leukocyte
leukocyte antigens
Prior art date
Application number
SG11201503448SA
Inventor
Hendrikus Theodorus Spierings
Original Assignee
Umc Utrecht Holding Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50684089&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201503448S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Umc Utrecht Holding Bv filed Critical Umc Utrecht Holding Bv
Publication of SG11201503448SA publication Critical patent/SG11201503448SA/en

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00—Subject matter not provided for in other groups of this subclass
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539—MHC-molecules, e.g. HLA-molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders
    • G01N2800/245—Transplantation related diseases, e.g. graft versus host disease
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/40—Population genetics; Linkage disequilibrium
SG11201503448SA 2012-11-08 2013-11-08 Method for prediction of an immune response against mismatched human leukocyte antigens SG11201503448SA (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261724103P 2012-11-08 2012-11-08
EP12075125 2012-11-08
EP12075124 2012-11-08
US201261729440P 2012-11-23 2012-11-23
EP12194008 2012-11-23
EP13075011 2013-01-24
PCT/EP2013/073386 WO2014072467A1 (en) 2012-11-08 2013-11-08 Method for prediction of an immune response against mismatched human leukocyte antigens

Publications (1)

Publication Number Publication Date
SG11201503448SA true SG11201503448SA (en) 2015-05-28

Family

ID=50684089

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201503448SA SG11201503448SA (en) 2012-11-08 2013-11-08 Method for prediction of an immune response against mismatched human leukocyte antigens

Country Status (13)

Country Link
US (1) US10120974B2 (en)
EP (1) EP2917735B2 (en)
JP (1) JP2016509470A (en)
KR (1) KR20150082549A (en)
CN (1) CN104838269A (en)
AU (1) AU2013343489A1 (en)
BR (1) BR112015010555A2 (en)
CA (1) CA2890222A1 (en)
HK (1) HK1211701A1 (en)
IL (1) IL238700A0 (en)
IN (1) IN2015DN03970A (en)
SG (1) SG11201503448SA (en)
WO (1) WO2014072467A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014072467A1 (en) 2012-11-08 2014-05-15 Umc Utrecht Holding B.V. Method for prediction of an immune response against mismatched human leukocyte antigens
EP3371598B1 (en) * 2015-11-05 2021-07-14 Pirche Ag Determining predicted indirectly recognized hla-derived peptides
CN111213210A (en) * 2017-09-06 2020-05-29 河谷控股Ip有限责任公司 HLA tissue matching and methods therefor
CN107893113B (en) * 2017-12-30 2020-12-25 广州博富瑞医学检验有限公司 HLA related SNP marker, detection primer pair and determination method thereof
KR102251584B1 (en) * 2018-11-21 2021-05-14 가톨릭대학교 산학협력단 Method for measuring and predicting antigen-specific T cell response restricted by HLA molecules
CN110305835A (en) * 2019-06-26 2019-10-08 中山大学附属第一医院 Kidney transplant donor specific urinates the preparation method and its application of source cell and its DNA
EP4059028A4 (en) * 2019-11-13 2023-12-20 The University of North Carolina at Chapel Hill Methods, systems, and computer readable media for enhanced virtual crossmatching using physical-crossmatch-outcome-data-derived model
CN111312332B (en) * 2020-02-13 2020-10-30 国家卫生健康委科学技术研究所 Biological information processing method and device based on HLA genes and terminal
KR20230040506A (en) * 2021-09-16 2023-03-23 가톨릭대학교 산학협력단 HLA class I and MICA/B null HEK-293T cell lines panel expressing single MICA or MICB alleles for detecting anti-MICA antibodies or anti-MICB antibodies and use thereof
CN113807468B (en) * 2021-10-15 2022-05-27 南京澄实生物科技有限公司 HLA antigen presentation prediction method and system based on multi-mode depth coding
EP4235675A1 (en) * 2022-02-28 2023-08-30 Pirche Ag A method for predicting hla b-cell epitopes considering allele-specific surface accessible residues

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8666674B2 (en) * 2009-07-28 2014-03-04 Promising Future, Llc Pairing processes for preparing reactive cytotoxic T cells
WO2014072467A1 (en) 2012-11-08 2014-05-15 Umc Utrecht Holding B.V. Method for prediction of an immune response against mismatched human leukocyte antigens

Also Published As

Publication number Publication date
CA2890222A1 (en) 2014-05-15
EP2917735A1 (en) 2015-09-16
BR112015010555A2 (en) 2017-07-11
HK1211701A1 (en) 2016-05-27
EP2917735B1 (en) 2018-07-18
IL238700A0 (en) 2015-06-30
IN2015DN03970A (en) 2015-10-02
US20150278434A1 (en) 2015-10-01
EP2917735B2 (en) 2021-09-22
CN104838269A (en) 2015-08-12
KR20150082549A (en) 2015-07-15
JP2016509470A (en) 2016-03-31
AU2013343489A1 (en) 2015-05-21
US10120974B2 (en) 2018-11-06
WO2014072467A1 (en) 2014-05-15

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